SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rti'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOS_A_VIAA1_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 4rti OXYGEN-EVOLVING
ENHANCER PROTEIN 2,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 12 TYR A  86
LEU A 156
GLN A  83
PHE A  74
ILE A  71
 None
 1.41A 1xosA-4rtiA:
undetectable		 1xosA-4rtiA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 4rti OXYGEN-EVOLVING
ENHANCER PROTEIN 2,
CHLOROPLASTIC
(Spinacia
oleracea) 		4 / 8 PHE A  74
PHE A  80
GLN A  64
TYR A  86
 None
 1.50A 2aoxA-4rtiA:
undetectable		 2aoxA-4rtiA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 4rti OXYGEN-EVOLVING
ENHANCER PROTEIN 2,
CHLOROPLASTIC
(Spinacia
oleracea) 		3 / 3 TYR A 127
THR A  72
GLU A  78
 None
 0.83A 4df3A-4rtiA:
undetectable		 4df3A-4rtiA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 4rti OXYGEN-EVOLVING
ENHANCER PROTEIN 2,
CHLOROPLASTIC
(Spinacia
oleracea) 		3 / 3 TYR A 127
THR A  72
GLU A  78
 None
 0.83A 4df3B-4rtiA:
undetectable		 4df3B-4rtiA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4rti OXYGEN-EVOLVING
ENHANCER PROTEIN 2,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 10 VAL A  30
VAL A  61
LEU A  59
GLY A  23
LEU A  28
 None
 1.08A 4ph9A-4rtiA:
undetectable		 4ph9A-4rtiA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4rti OXYGEN-EVOLVING
ENHANCER PROTEIN 2,
CHLOROPLASTIC
(Spinacia
oleracea) 		5 / 10 VAL A  30
VAL A  61
LEU A  59
GLY A  23
LEU A  28
 None
 1.08A 4ph9B-4rtiA:
undetectable		 4ph9B-4rtiA:
16.33