SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ru3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D33_B_MTLB870_0 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	4ru3	PUNCTURING PROTEIN GP41 (Pseudomonas virus SN)	4 / 7	SER A 160 ARG A 162 ASN A 165 ILE A 166	None	0.89A	4d33B-4ru3A: undetectable	4d33B-4ru3A: 21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D39_A_MTLA870_0 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	4ru3	PUNCTURING PROTEIN GP41 (Pseudomonas virus SN)	4 / 8	SER A 160 ARG A 162 ASN A 165 ILE A 166	None	0.86A	4d39A-4ru3A: undetectable	4d39A-4ru3A: 21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D39_B_MTLB870_0 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	4ru3	PUNCTURING PROTEIN GP41 (Pseudomonas virus SN)	4 / 7	SER A 160 ARG A 162 ASN A 165 ILE A 166	None	0.89A	4d39B-4ru3A: undetectable	4d39B-4ru3A: 21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ODQ_A_ACTA703_0 (HETERODISULFIDE REDUCTASE, SUBUNIT A)	4ru3	PUNCTURING PROTEIN GP41 (Pseudomonas virus SN)	4 / 6	ARG A 68 ALA A 38 PRO A 54 PHE A 125	None	1.37A	5odqA-4ru3A: undetectable	5odqA-4ru3A: 16.07

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4D33_B_MTLB870_0","NITRIC OXIDE SYNTHASE, ENDOTHELIAL","4ru3","PUNCTURING PROTEIN GP41","Pseudomonas virus SN",4,"SER A 160;ARG A 162;ASN A 165;ILE A 166","None","0.89A","4d33B-4ru3A:undetectable","4d33B-4ru3A:21.36"],["4D39_A_MTLA870_0","NITRIC OXIDE SYNTHASE, ENDOTHELIAL","4ru3","PUNCTURING PROTEIN GP41","Pseudomonas virus SN",4,"SER A 160;ARG A 162;ASN A 165;ILE A 166","None","0.86A","4d39A-4ru3A:undetectable","4d39A-4ru3A:21.36"],["4D39_B_MTLB870_0","NITRIC OXIDE SYNTHASE, ENDOTHELIAL","4ru3","PUNCTURING PROTEIN GP41","Pseudomonas virus SN",4,"SER A 160;ARG A 162;ASN A 165;ILE A 166","None","0.89A","4d39B-4ru3A:undetectable","4d39B-4ru3A:21.36"],["5ODQ_A_ACTA703_0","HETERODISULFIDE REDUCTASE, SUBUNIT A","4ru3","PUNCTURING PROTEIN GP41","Pseudomonas virus SN",4,"ARG A  68;ALA A  38;PRO A  54;PHE A 125","None","1.37A","5odqA-4ru3A:undetectable","5odqA-4ru3A:16.07"]]