SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rus'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VIF_A_FOLA1_0
(DIHYDROFOLATE
REDUCTASE)		 4rus FISH-EGG LECTIN
(Cyprinus
carpio) 		3 / 3 GLN A 118
ILE A  98
TYR A  99
 None
None
1PE  A 305 ( 4.0A)
 0.73A 1vifA-4rusA:
undetectable		 1vifA-4rusA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)		 4rus FISH-EGG LECTIN
(Cyprinus
carpio) 		5 / 12 PHE A  30
GLY A  70
GLY A  42
SER A  41
PHE A  47
 None
 1.10A 3e23A-4rusA:
undetectable		 3e23A-4rusA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4rus FISH-EGG LECTIN
(Cyprinus
carpio) 		5 / 12 GLN A  80
GLY A  91
GLY A  56
ALA A  52
SER A  17
 None
 1.11A 3sudB-4rusA:
undetectable		 3sudB-4rusA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4rus FISH-EGG LECTIN
(Cyprinus
carpio) 		5 / 12 GLN A  80
GLY A  91
GLY A  56
ALA A  52
SER A  17
 None
 1.23A 3sueD-4rusA:
undetectable		 3sueD-4rusA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4rus FISH-EGG LECTIN
(Cyprinus
carpio) 		5 / 12 GLY A  16
SER A 216
HIS A 214
HIS A  46
TYR A 125
 None
CA  A 303 ( 4.3A)
None
None
None
 1.29A 4emaA-4rusA:
undetectable		 4emaA-4rusA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4rus FISH-EGG LECTIN
(Cyprinus
carpio) 		4 / 6 LEU A  55
LEU A  78
PHE A 159
MET A 145
 None
1PE  A 305 (-4.4A)
None
None
 1.10A 4o1zA-4rusA:
undetectable		 4o1zA-4rusA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 4rus FISH-EGG LECTIN
(Cyprinus
carpio) 		4 / 5 GLY A 175
ALA A 172
GLY A 129
PRO A 130
 None
 0.92A 4u9uA-4rusA:
undetectable		 4u9uA-4rusA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 4rus FISH-EGG LECTIN
(Cyprinus
carpio) 		4 / 5 GLY A 175
ALA A 172
GLY A 129
PRO A 130
 None
 0.93A 4u9uB-4rusA:
undetectable		 4u9uB-4rusA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 4rus FISH-EGG LECTIN
(Cyprinus
carpio) 		4 / 7 GLU A 170
SER A  48
TYR A 125
ALA A  90
 CA  A 303 (-3.0A)
CA  A 303 ( 4.1A)
None
None
 0.98A 5e26A-4rusA:
undetectable
5e26B-4rusA:
undetectable		 5e26A-4rusA:
20.82
5e26B-4rusA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 4rus FISH-EGG LECTIN
(Cyprinus
carpio) 		5 / 7 TYR A 125
ALA A  90
GLU A 170
SER A  48
GLY A  56
 None
None
CA  A 303 (-3.0A)
CA  A 303 ( 4.1A)
None
 1.26A 5e26A-4rusA:
undetectable
5e26B-4rusA:
undetectable		 5e26A-4rusA:
20.82
5e26B-4rusA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 4rus FISH-EGG LECTIN
(Cyprinus
carpio) 		5 / 7 GLU A 170
SER A  48
GLY A  56
TYR A 125
ALA A  90
 CA  A 303 (-3.0A)
CA  A 303 ( 4.1A)
None
None
None
 1.19A 5e26C-4rusA:
undetectable
5e26D-4rusA:
undetectable		 5e26C-4rusA:
20.82
5e26D-4rusA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_0
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 4rus FISH-EGG LECTIN
(Cyprinus
carpio) 		5 / 12 GLY A 179
LEU A 186
VAL A 215
HIS A 214
LEU A 224
 None
 1.18A 5ubbA-4rusA:
undetectable		 5ubbA-4rusA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4rus FISH-EGG LECTIN
(Cyprinus
carpio) 		5 / 12 GLY A  16
SER A 216
HIS A 214
HIS A  46
TYR A 125
 None
CA  A 303 ( 4.3A)
None
None
None
 1.12A 6md4A-4rusA:
undetectable		 6md4A-4rusA:
14.67