SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rv1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 150
ARG A 108
GLU A 143
ALA A  69
GLU A 105
 None
 1.27A 1nncA-4rv1A:
undetectable		 1nncA-4rv1A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 192
ARG A 150
GLU A 185
ALA A 111
GLU A 147
 None
 1.27A 1nncA-4rv1A:
undetectable		 1nncA-4rv1A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 234
ARG A 192
GLU A 227
ALA A 153
GLU A 189
 None
 1.34A 1nncA-4rv1A:
undetectable		 1nncA-4rv1A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 276
ARG A 234
GLU A 269
ALA A 195
GLU A 231
 None
 1.32A 1nncA-4rv1A:
undetectable		 1nncA-4rv1A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 402
ARG A 360
GLU A 395
ALA A 321
GLU A 357
 None
 1.30A 1nncA-4rv1A:
undetectable		 1nncA-4rv1A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_A_BCZA1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 150
ARG A 108
GLU A 143
ALA A  69
GLU A 105
 None
 1.33A 3k39A-4rv1A:
undetectable		 3k39A-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_A_BCZA1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 192
ARG A 150
GLU A 185
ALA A 111
GLU A 147
 None
 1.32A 3k39A-4rv1A:
undetectable		 3k39A-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_A_BCZA1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 234
ARG A 192
GLU A 227
ALA A 153
GLU A 189
 None
 1.41A 3k39A-4rv1A:
undetectable		 3k39A-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_A_BCZA1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 276
ARG A 234
GLU A 269
ALA A 195
GLU A 231
 None
 1.44A 3k39A-4rv1A:
undetectable		 3k39A-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_A_BCZA1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 276
ARG A 234
GLU A 269
ALA A 235
GLU A 231
 None
 1.40A 3k39A-4rv1A:
undetectable		 3k39A-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_A_BCZA1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 402
ARG A 360
GLU A 395
ALA A 321
GLU A 357
 None
 1.34A 3k39A-4rv1A:
undetectable		 3k39A-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_C_BCZC1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 192
ARG A 150
GLU A 185
ALA A 111
GLU A 147
 None
 1.34A 3k39C-4rv1A:
undetectable		 3k39C-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_C_BCZC1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 276
ARG A 234
GLU A 269
ALA A 195
GLU A 231
 None
 1.46A 3k39C-4rv1A:
undetectable		 3k39C-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_C_BCZC1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 402
ARG A 360
GLU A 395
ALA A 321
GLU A 357
 None
 1.36A 3k39C-4rv1A:
undetectable		 3k39C-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_D_BCZD1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 150
ARG A 108
GLU A 143
ALA A  69
GLU A 105
 None
 1.33A 3k39D-4rv1A:
undetectable		 3k39D-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_D_BCZD1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 192
ARG A 150
GLU A 185
ALA A 111
GLU A 147
 None
 1.32A 3k39D-4rv1A:
undetectable		 3k39D-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_D_BCZD1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 234
ARG A 192
GLU A 227
ALA A 153
GLU A 189
 None
 1.41A 3k39D-4rv1A:
undetectable		 3k39D-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_D_BCZD1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 276
ARG A 234
GLU A 269
ALA A 195
GLU A 231
 None
 1.44A 3k39D-4rv1A:
undetectable		 3k39D-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_D_BCZD1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 402
ARG A 360
GLU A 395
ALA A 321
GLU A 357
 None
 1.34A 3k39D-4rv1A:
undetectable		 3k39D-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_E_BCZE1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 150
ARG A 108
GLU A 143
ALA A  69
GLU A 105
 None
 1.33A 3k39E-4rv1A:
undetectable		 3k39E-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_E_BCZE1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 192
ARG A 150
GLU A 185
ALA A 111
GLU A 147
 None
 1.32A 3k39E-4rv1A:
undetectable		 3k39E-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_E_BCZE1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 234
ARG A 192
GLU A 227
ALA A 153
GLU A 189
 None
 1.41A 3k39E-4rv1A:
undetectable		 3k39E-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_E_BCZE1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 276
ARG A 234
GLU A 269
ALA A 195
GLU A 231
 None
 1.44A 3k39E-4rv1A:
undetectable		 3k39E-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_E_BCZE1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 402
ARG A 360
GLU A 395
ALA A 321
GLU A 357
 None
 1.34A 3k39E-4rv1A:
undetectable		 3k39E-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_F_BCZF1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 150
ARG A 108
GLU A 143
ALA A  69
GLU A 105
 None
 1.34A 3k39F-4rv1A:
undetectable		 3k39F-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_F_BCZF1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 192
ARG A 150
GLU A 185
ALA A 111
GLU A 147
 None
 1.33A 3k39F-4rv1A:
undetectable		 3k39F-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_F_BCZF1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 234
ARG A 192
GLU A 227
ALA A 153
GLU A 189
 None
 1.42A 3k39F-4rv1A:
undetectable		 3k39F-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_F_BCZF1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 276
ARG A 234
GLU A 269
ALA A 195
GLU A 231
 None
 1.45A 3k39F-4rv1A:
undetectable		 3k39F-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_F_BCZF1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 402
ARG A 360
GLU A 395
ALA A 321
GLU A 357
 None
 1.35A 3k39F-4rv1A:
undetectable		 3k39F-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_G_BCZG1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 150
ARG A 108
GLU A 143
ALA A  69
GLU A 105
 None
 1.31A 3k39G-4rv1A:
undetectable		 3k39G-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_G_BCZG1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 192
ARG A 150
GLU A 185
ALA A 111
GLU A 147
 None
 1.31A 3k39G-4rv1A:
undetectable		 3k39G-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_G_BCZG1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 234
ARG A 192
GLU A 227
ALA A 153
GLU A 189
 None
 1.40A 3k39G-4rv1A:
undetectable		 3k39G-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_G_BCZG1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 276
ARG A 234
GLU A 269
ALA A 195
GLU A 231
 None
 1.43A 3k39G-4rv1A:
undetectable		 3k39G-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_G_BCZG1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 402
ARG A 360
GLU A 395
ALA A 321
GLU A 357
 None
 1.34A 3k39G-4rv1A:
undetectable		 3k39G-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_H_BCZH1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 150
ARG A 108
GLU A 143
ALA A  69
GLU A 105
 None
 1.33A 3k39H-4rv1A:
undetectable		 3k39H-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_H_BCZH1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 192
ARG A 150
GLU A 185
ALA A 111
GLU A 147
 None
 1.32A 3k39H-4rv1A:
undetectable		 3k39H-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_H_BCZH1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 234
ARG A 192
GLU A 227
ALA A 153
GLU A 189
 None
 1.41A 3k39H-4rv1A:
undetectable		 3k39H-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_H_BCZH1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 276
ARG A 234
GLU A 269
ALA A 195
GLU A 231
 None
 1.44A 3k39H-4rv1A:
undetectable		 3k39H-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_H_BCZH1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 402
ARG A 360
GLU A 395
ALA A 321
GLU A 357
 None
 1.34A 3k39H-4rv1A:
undetectable		 3k39H-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_I_BCZI1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 192
ARG A 150
GLU A 185
ALA A 111
GLU A 147
 None
 1.32A 3k39I-4rv1A:
undetectable		 3k39I-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_I_BCZI1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 276
ARG A 234
GLU A 269
ALA A 195
GLU A 231
 None
 1.44A 3k39I-4rv1A:
undetectable		 3k39I-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_I_BCZI1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 402
ARG A 360
GLU A 395
ALA A 321
GLU A 357
 None
 1.34A 3k39I-4rv1A:
undetectable		 3k39I-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 150
ARG A 108
GLU A 143
ALA A  69
GLU A 105
 None
 1.33A 3k39J-4rv1A:
undetectable		 3k39J-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 192
ARG A 150
GLU A 185
ALA A 111
GLU A 147
 None
 1.32A 3k39J-4rv1A:
undetectable		 3k39J-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 234
ARG A 192
GLU A 227
ALA A 153
GLU A 189
 None
 1.41A 3k39J-4rv1A:
undetectable		 3k39J-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 276
ARG A 234
GLU A 269
ALA A 195
GLU A 231
 None
 1.44A 3k39J-4rv1A:
undetectable		 3k39J-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 402
ARG A 360
GLU A 395
ALA A 321
GLU A 357
 None
 1.34A 3k39J-4rv1A:
undetectable		 3k39J-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_K_BCZK1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 150
ARG A 108
GLU A 143
ALA A  69
GLU A 105
 None
 1.33A 3k39K-4rv1A:
undetectable		 3k39K-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_K_BCZK1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 192
ARG A 150
GLU A 185
ALA A 111
GLU A 147
 None
 1.32A 3k39K-4rv1A:
undetectable		 3k39K-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_K_BCZK1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 234
ARG A 192
GLU A 227
ALA A 153
GLU A 189
 None
 1.41A 3k39K-4rv1A:
undetectable		 3k39K-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_K_BCZK1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 276
ARG A 234
GLU A 269
ALA A 195
GLU A 231
 None
 1.44A 3k39K-4rv1A:
undetectable		 3k39K-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_K_BCZK1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 402
ARG A 360
GLU A 395
ALA A 321
GLU A 357
 None
 1.34A 3k39K-4rv1A:
undetectable		 3k39K-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_L_BCZL1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 150
ARG A 108
GLU A 143
ALA A  69
GLU A 105
 None
 1.31A 3k39L-4rv1A:
undetectable		 3k39L-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_L_BCZL1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 192
ARG A 150
GLU A 185
ALA A 111
GLU A 147
 None
 1.30A 3k39L-4rv1A:
undetectable		 3k39L-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_L_BCZL1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 234
ARG A 192
GLU A 227
ALA A 153
GLU A 189
 None
 1.39A 3k39L-4rv1A:
undetectable		 3k39L-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_L_BCZL1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 276
ARG A 234
GLU A 269
ALA A 195
GLU A 231
 None
 1.42A 3k39L-4rv1A:
undetectable		 3k39L-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_L_BCZL1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 402
ARG A 360
GLU A 395
ALA A 321
GLU A 357
 None
 1.32A 3k39L-4rv1A:
undetectable		 3k39L-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_M_BCZM1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 150
ARG A 108
GLU A 143
ALA A  69
GLU A 105
 None
 1.32A 3k39M-4rv1A:
undetectable		 3k39M-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_M_BCZM1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 192
ARG A 150
GLU A 185
ALA A 111
GLU A 147
 None
 1.31A 3k39M-4rv1A:
undetectable		 3k39M-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_M_BCZM1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 234
ARG A 192
GLU A 227
ALA A 153
GLU A 189
 None
 1.40A 3k39M-4rv1A:
undetectable		 3k39M-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_M_BCZM1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 276
ARG A 234
GLU A 269
ALA A 195
GLU A 231
 None
 1.43A 3k39M-4rv1A:
undetectable		 3k39M-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_M_BCZM1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 276
ARG A 234
GLU A 269
ALA A 235
GLU A 231
 None
 1.40A 3k39M-4rv1A:
undetectable		 3k39M-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_M_BCZM1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 402
ARG A 360
GLU A 395
ALA A 321
GLU A 357
 None
 1.33A 3k39M-4rv1A:
undetectable		 3k39M-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_N_BCZN1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 150
ARG A 108
GLU A 143
ALA A  69
GLU A 105
 None
 1.33A 3k39N-4rv1A:
undetectable		 3k39N-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_N_BCZN1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 192
ARG A 150
GLU A 185
ALA A 111
GLU A 147
 None
 1.32A 3k39N-4rv1A:
undetectable		 3k39N-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_N_BCZN1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 234
ARG A 192
GLU A 227
ALA A 153
GLU A 189
 None
 1.41A 3k39N-4rv1A:
undetectable		 3k39N-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_N_BCZN1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 276
ARG A 234
GLU A 269
ALA A 195
GLU A 231
 None
 1.44A 3k39N-4rv1A:
undetectable		 3k39N-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_N_BCZN1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 402
ARG A 360
GLU A 395
ALA A 321
GLU A 357
 None
 1.35A 3k39N-4rv1A:
undetectable		 3k39N-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_O_BCZO1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 192
ARG A 150
GLU A 185
ALA A 111
GLU A 147
 None
 1.33A 3k39O-4rv1A:
undetectable		 3k39O-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_O_BCZO1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 276
ARG A 234
GLU A 269
ALA A 195
GLU A 231
 None
 1.45A 3k39O-4rv1A:
undetectable		 3k39O-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_O_BCZO1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 276
ARG A 234
GLU A 269
ALA A 235
GLU A 231
 None
 1.40A 3k39O-4rv1A:
undetectable		 3k39O-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_O_BCZO1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 402
ARG A 360
GLU A 395
ALA A 321
GLU A 357
 None
 1.35A 3k39O-4rv1A:
undetectable		 3k39O-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_P_BCZP1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 192
ARG A 150
GLU A 185
ALA A 111
GLU A 147
 None
 1.32A 3k39P-4rv1A:
undetectable		 3k39P-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_P_BCZP1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 276
ARG A 234
GLU A 269
ALA A 195
GLU A 231
 None
 1.44A 3k39P-4rv1A:
undetectable		 3k39P-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_P_BCZP1001_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 402
ARG A 360
GLU A 395
ALA A 321
GLU A 357
 None
 1.34A 3k39P-4rv1A:
undetectable		 3k39P-4rv1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		4 / 7 LEU A 178
ILE A 155
VAL A 130
LEU A 133
 None
 0.67A 3r9vA-4rv1A:
undetectable
3r9vB-4rv1A:
undetectable		 3r9vA-4rv1A:
23.15
3r9vB-4rv1A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		4 / 7 LEU A 220
ILE A 197
VAL A 172
LEU A 175
 None
 0.69A 3r9vA-4rv1A:
undetectable
3r9vB-4rv1A:
undetectable		 3r9vA-4rv1A:
23.15
3r9vB-4rv1A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		4 / 7 LEU A 262
ILE A 239
VAL A 214
LEU A 217
 None
 0.65A 3r9vA-4rv1A:
undetectable
3r9vB-4rv1A:
undetectable		 3r9vA-4rv1A:
23.15
3r9vB-4rv1A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 GLY A 284
ILE A 334
GLY A 326
ALA A 321
ALA A 361
 None
 1.08A 3sueA-4rv1A:
undetectable		 3sueA-4rv1A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1R_A_LZUA801_1
(MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 VAL A 132
LYS A 135
ALA A 111
LEU A  91
LEU A  95
 None
 1.18A 4i1rA-4rv1A:
undetectable		 4i1rA-4rv1A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 150
ARG A 108
GLU A 143
ALA A  69
GLU A 105
 None
 1.13A 4mx0A-4rv1A:
undetectable		 4mx0A-4rv1A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 192
ARG A 150
GLU A 185
ALA A 111
GLU A 147
 None
 1.10A 4mx0A-4rv1A:
undetectable		 4mx0A-4rv1A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 234
ARG A 192
GLU A 227
ALA A 153
GLU A 189
 None
 1.21A 4mx0A-4rv1A:
undetectable		 4mx0A-4rv1A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 276
ARG A 234
GLU A 269
ALA A 195
GLU A 231
 None
 1.21A 4mx0A-4rv1A:
undetectable		 4mx0A-4rv1A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 11 GLY A 129
ALA A 165
VAL A 130
GLU A 131
ILE A 124
 None
 1.19A 5i3cC-4rv1A:
undetectable		 5i3cC-4rv1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 GLY A 200
ILE A 250
GLY A 242
ALA A 237
ALA A 277
 None
 1.07A 6c2mD-4rv1A:
undetectable		 6c2mD-4rv1A:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 GLY A 242
ILE A 292
GLY A 284
ALA A 279
ALA A 319
 None
 1.01A 6c2mD-4rv1A:
undetectable		 6c2mD-4rv1A:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 GLY A 284
ILE A 334
GLY A 326
ALA A 321
ALA A 361
 None
 1.01A 6c2mD-4rv1A:
undetectable		 6c2mD-4rv1A:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 GLY A 326
ILE A 376
GLY A 368
ALA A 363
ALA A 403
 None
 1.05A 6c2mD-4rv1A:
undetectable		 6c2mD-4rv1A:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ILE A  71
GLY A  44
ALA A  43
ASP A  42
ILE A  29
 None
 1.06A 6dwnD-4rv1A:
undetectable		 6dwnD-4rv1A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ILE A 281
GLY A 254
ALA A 253
ASP A 252
ILE A 239
 None
 1.10A 6dwnD-4rv1A:
undetectable		 6dwnD-4rv1A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ILE A 407
GLY A 380
ALA A 379
ASP A 378
ILE A 365
 None
 1.07A 6dwnD-4rv1A:
undetectable		 6dwnD-4rv1A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		4 / 6 ASP A  15
GLN A  19
LEU A  52
SER A  55
 None
 1.25A 6ekuA-4rv1A:
undetectable		 6ekuA-4rv1A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 10 ALA A  65
VAL A  46
ILE A  79
ALA A  78
ALA A  30
 None
 1.10A 6h1lA-4rv1A:
undetectable		 6h1lA-4rv1A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 150
ARG A 108
GLU A 143
ALA A  69
GLU A 105
 None
 1.28A 6hcxA-4rv1A:
undetectable		 6hcxA-4rv1A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 234
ARG A 192
GLU A 227
ALA A 153
GLU A 189
 None
 1.35A 6hcxA-4rv1A:
undetectable		 6hcxA-4rv1A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_0
(NEURAMINIDASE)		 4rv1 ENGINEERED PROTEIN
OR497
(synthetic
construct) 		5 / 12 ARG A 276
ARG A 234
GLU A 269
ALA A 195
GLU A 231
 None
 1.34A 6hcxA-4rv1A:
undetectable		 6hcxA-4rv1A:
12.14