SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rv3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 7 PHE A  63
VAL A 204
ASP A  65
ILE A 279
 None
 0.92A 1p7rA-4rv3A:
undetectable		 1p7rA-4rv3A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		5 / 12 LEU A 100
GLY A  60
ILE A 108
THR A 153
PRO A 152
 None
 1.07A 1p91B-4rv3A:
undetectable		 1p91B-4rv3A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 7 GLY A 284
GLN A  49
ILE A 293
VAL A 294
 None
 1.05A 1rxcF-4rv3A:
undetectable		 1rxcF-4rv3A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 7 PHE A 164
PHE A  63
VAL A 280
SER A 241
 None
None
None
INS  A 402 ( 4.7A)
 0.99A 1wrlA-4rv3A:
undetectable
1wrlB-4rv3A:
undetectable		 1wrlA-4rv3A:
14.78
1wrlB-4rv3A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_A_ACTA601_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 7 TYR A 134
SER A  71
ALA A  70
ASN A  74
 None
 1.05A 2i91A-4rv3A:
undetectable		 2i91A-4rv3A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_B_ACTB602_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 7 TYR A 134
SER A  71
ALA A  70
ASN A  74
 None
 1.05A 2i91B-4rv3A:
undetectable		 2i91B-4rv3A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		5 / 12 ILE A  76
TYR A  84
ALA A  72
SER A  71
ASP A  95
 None
 1.44A 2iyfB-4rv3A:
undetectable		 2iyfB-4rv3A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 6 GLY A 284
GLN A  49
ILE A 293
VAL A 294
 None
 1.09A 3kvvA-4rv3A:
undetectable		 3kvvA-4rv3A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 6 GLY A 284
GLN A  49
ILE A 293
VAL A 294
 None
 1.11A 3kvvB-4rv3A:
undetectable		 3kvvB-4rv3A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 6 GLY A 284
GLN A  49
ILE A 293
VAL A 294
 None
 1.12A 3kvvC-4rv3A:
undetectable		 3kvvC-4rv3A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 6 GLY A 284
GLN A  49
ILE A 293
VAL A 294
 None
 1.08A 3kvvD-4rv3A:
undetectable		 3kvvD-4rv3A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 6 GLY A 284
GLN A  49
ILE A 293
VAL A 294
 None
 1.11A 3kvvE-4rv3A:
undetectable		 3kvvE-4rv3A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 6 GLY A 284
GLN A  49
ILE A 293
VAL A 294
 None
 1.09A 3kvvF-4rv3A:
undetectable		 3kvvF-4rv3A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		3 / 3 ASP A 115
ARG A 166
LYS A 113
 None
INS  A 402 (-2.6A)
INS  A 402 (-3.9A)
 1.15A 3wipG-4rv3A:
undetectable		 3wipG-4rv3A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 7 GLY A 284
GLN A  49
ILE A 293
VAL A 294
 None
 1.08A 4e1vB-4rv3A:
undetectable		 4e1vB-4rv3A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 6 GLY A 284
GLN A  49
ILE A 293
VAL A 294
 None
 1.09A 4e1vF-4rv3A:
undetectable		 4e1vF-4rv3A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 8 GLY A  60
PHE A  64
ILE A 108
PHE A  92
 None
 0.88A 4fglD-4rv3A:
undetectable		 4fglD-4rv3A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 7 GLY A  60
PHE A  64
ILE A 108
PHE A  92
 None
 0.86A 4fglC-4rv3A:
undetectable		 4fglC-4rv3A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 8 ASP A 281
ASP A 115
ASP A  65
ASP A 187
 None
 1.12A 4gkhC-4rv3A:
0.4
4gkhK-4rv3A:
undetectable		 4gkhC-4rv3A:
22.73
4gkhK-4rv3A:
22.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I90_A_ACTA500_0
(1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		3 / 3 LYS A 113
ARG A 166
TRP A 185
 INS  A 402 (-3.9A)
INS  A 402 (-2.6A)
INS  A 402 ( 4.9A)
 0.28A 4i90A-4rv3A:
54.5		 4i90A-4rv3A:
99.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I90_A_ACTA501_0
(1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		5 / 5 LEU A  37
LYS A  38
ASP A  39
LYS A  42
HIS A  86
 ACT  A 401 (-3.8A)
None
None
ACT  A 401 (-2.9A)
ACT  A 401 (-4.0A)
 0.52A 4i90A-4rv3A:
54.5		 4i90A-4rv3A:
99.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 6 GLY A  60
PHE A  64
ILE A 108
PHE A  92
 None
 0.96A 4qogA-4rv3A:
undetectable
4qogB-4rv3A:
undetectable		 4qogA-4rv3A:
22.76
4qogB-4rv3A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_ACTA202_0
(RETINOL-BINDING
PROTEIN 2)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 6 TYR A 176
GLU A 156
THR A 153
LEU A  21
 None
 1.42A 4qztA-4rv3A:
undetectable		 4qztA-4rv3A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_1
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		5 / 12 VAL A 237
THR A  48
GLN A  49
ILE A 259
ASN A 260
 None
None
None
PF5  A 258 ( 4.4A)
None
 1.12A 4s0vA-4rv3A:
undetectable		 4s0vA-4rv3A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 6 ASP A  31
ALA A  46
THR A  48
THR A 252
 INS  A 402 ( 4.3A)
None
None
None
 0.98A 4w5qA-4rv3A:
undetectable		 4w5qA-4rv3A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 6 ASP A  31
ALA A  46
THR A  48
THR A 252
 INS  A 402 ( 4.3A)
None
None
None
 0.97A 4w5rA-4rv3A:
undetectable		 4w5rA-4rv3A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 6 ASP A  31
ALA A  46
THR A  48
THR A 252
 INS  A 402 ( 4.3A)
None
None
None
 0.96A 4w5tA-4rv3A:
undetectable		 4w5tA-4rv3A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 6 ASP A  31
ALA A  46
THR A  48
THR A 252
 INS  A 402 ( 4.3A)
None
None
None
 1.00A 4z4cA-4rv3A:
undetectable		 4z4cA-4rv3A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 6 ASP A  31
ALA A  46
THR A  48
THR A 252
 INS  A 402 ( 4.3A)
None
None
None
 0.96A 4z4fA-4rv3A:
undetectable		 4z4fA-4rv3A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 5 ASP A  31
ALA A  46
THR A  48
THR A 252
 INS  A 402 ( 4.3A)
None
None
None
 0.99A 4z4gA-4rv3A:
undetectable		 4z4gA-4rv3A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		4 / 6 ASP A  31
ALA A  46
THR A  48
THR A 252
 INS  A 402 ( 4.3A)
None
None
None
 0.98A 4z4iA-4rv3A:
undetectable		 4z4iA-4rv3A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		5 / 12 ALA A  96
ASP A  65
GLY A  33
SER A  34
THR A  48
 None
 1.15A 5hfjB-4rv3A:
undetectable		 5hfjB-4rv3A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_E_SAME301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		5 / 12 ALA A  96
ASP A  65
GLY A  33
SER A  34
THR A  48
 None
 1.06A 5hfjE-4rv3A:
undetectable		 5hfjE-4rv3A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		5 / 12 ASP A  65
ASP A  50
GLY A 284
THR A 286
SER A  29
 None
 1.39A 5hfjH-4rv3A:
undetectable		 5hfjH-4rv3A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		3 / 3 ARG A 166
HIS A  30
ARG A  67
 INS  A 402 (-2.6A)
INS  A 402 (-3.6A)
INS  A 402 (-3.5A)
 0.73A 5iaoC-4rv3A:
undetectable		 5iaoC-4rv3A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		3 / 3 ARG A 166
HIS A  30
ARG A  67
 INS  A 402 (-2.6A)
INS  A 402 (-3.6A)
INS  A 402 (-3.5A)
 0.75A 5iaoF-4rv3A:
undetectable		 5iaoF-4rv3A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		3 / 3 LYS A  51
LYS A  58
SER A  59
 None
 1.42A 5odiA-4rv3A:
2.4		 5odiA-4rv3A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		3 / 3 HIS A  80
ASP A  31
HIS A  30
 None
INS  A 402 ( 4.3A)
INS  A 402 (-3.6A)
 0.71A 5oexB-4rv3A:
undetectable		 5oexB-4rv3A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		3 / 3 HIS A  80
ASP A  31
HIS A  30
 None
INS  A 402 ( 4.3A)
INS  A 402 (-3.6A)
 0.69A 5oexC-4rv3A:
undetectable		 5oexC-4rv3A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		3 / 3 HIS A  80
ASP A  31
HIS A  30
 None
INS  A 402 ( 4.3A)
INS  A 402 (-3.6A)
 0.67A 5oexD-4rv3A:
undetectable		 5oexD-4rv3A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Staphylococcus
aureus) 		3 / 3 ASP A  31
PHE A 239
ARG A 166
 INS  A 402 ( 4.3A)
INS  A 402 ( 4.1A)
INS  A 402 (-2.6A)
 1.08A 5yw0A-4rv3A:
undetectable		 5yw0A-4rv3A:
22.13