SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4rwt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 6 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.96A 1v54A-4rwtC:
undetectable
1v54J-4rwtC:
undetectable		 1v54A-4rwtC:
19.44
1v54J-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 7 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.84A 1v54N-4rwtC:
undetectable
1v54W-4rwtC:
undetectable		 1v54N-4rwtC:
19.44
1v54W-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 6 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.99A 2dyrA-4rwtC:
undetectable
2dyrJ-4rwtC:
undetectable		 2dyrA-4rwtC:
19.44
2dyrJ-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 7 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.94A 2dyrN-4rwtC:
undetectable
2dyrW-4rwtC:
undetectable		 2dyrN-4rwtC:
19.44
2dyrW-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 6 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.99A 2dysA-4rwtC:
undetectable
2dysJ-4rwtC:
undetectable		 2dysA-4rwtC:
19.44
2dysJ-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 6 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.86A 2dysN-4rwtC:
undetectable
2dysW-4rwtC:
undetectable		 2dysN-4rwtC:
19.44
2dysW-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 6 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.95A 2eijA-4rwtC:
undetectable
2eijJ-4rwtC:
undetectable		 2eijA-4rwtC:
19.44
2eijJ-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 8 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.85A 2eijN-4rwtC:
undetectable
2eijW-4rwtC:
undetectable		 2eijN-4rwtC:
19.44
2eijW-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 7 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.90A 2eikA-4rwtC:
undetectable
2eikJ-4rwtC:
undetectable		 2eikA-4rwtC:
19.44
2eikJ-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 8 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.84A 2eikN-4rwtC:
undetectable
2eikW-4rwtC:
undetectable		 2eikN-4rwtC:
19.44
2eikW-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 6 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.93A 2eilA-4rwtC:
undetectable
2eilJ-4rwtC:
undetectable		 2eilA-4rwtC:
19.44
2eilJ-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 8 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.85A 2eilN-4rwtC:
undetectable
2eilW-4rwtC:
undetectable		 2eilN-4rwtC:
19.44
2eilW-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 5 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.90A 2eimJ-4rwtC:
undetectable		 2eimJ-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 5 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.88A 2eimW-4rwtC:
undetectable		 2eimW-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 6 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.91A 2einN-4rwtC:
undetectable
2einW-4rwtC:
undetectable		 2einN-4rwtC:
19.44
2einW-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1291_1
(FICOLIN-2)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 4 ASP C 222
LEU C 254
GLY C 250
ARG C 258
 None
 1.31A 2j2pD-4rwtC:
undetectable
2j2pE-4rwtC:
undetectable		 2j2pD-4rwtC:
17.22
2j2pE-4rwtC:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 6 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 1.02A 2zxwA-4rwtC:
undetectable
2zxwJ-4rwtC:
undetectable		 2zxwA-4rwtC:
19.44
2zxwJ-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_A_VD3A2001_1
(VITAMIN D
HYDROXYLASE)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		5 / 12 ILE C 248
ASN C 185
ILE C 228
ALA C 229
LEU C 269
 None
 1.02A 3a50A-4rwtC:
undetectable		 3a50A-4rwtC:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_A_VD3A2001_1
(VITAMIN D
HYDROXYLASE)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		5 / 12 THR C 218
ILE C 248
ASN C 185
ILE C 228
LEU C 269
 None
 0.84A 3a50A-4rwtC:
undetectable		 3a50A-4rwtC:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_C_VD3C2001_1
(VITAMIN D
HYDROXYLASE)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		5 / 11 THR C 218
ILE C 248
ASN C 185
ILE C 228
LEU C 269
 None
 0.83A 3a50C-4rwtC:
undetectable		 3a50C-4rwtC:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_D_VD3D2001_1
(VITAMIN D
HYDROXYLASE)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		5 / 12 ILE C 248
ASN C 185
ILE C 228
ALA C 229
LEU C 269
 None
 0.90A 3a50D-4rwtC:
undetectable		 3a50D-4rwtC:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		5 / 12 THR C 218
ILE C 248
ASN C 185
ILE C 228
LEU C 269
 None
 0.87A 3a50E-4rwtC:
undetectable		 3a50E-4rwtC:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		5 / 11 THR C 218
ILE C 248
ASN C 185
ILE C 228
LEU C 269
 None
 0.90A 3a51A-4rwtC:
undetectable		 3a51A-4rwtC:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		5 / 12 THR C 218
ILE C 248
ASN C 185
ILE C 228
LEU C 269
 None
 0.86A 3a51C-4rwtC:
undetectable		 3a51C-4rwtC:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		5 / 12 THR C 218
ILE C 248
ASN C 185
ILE C 228
LEU C 269
 None
 0.75A 3a51D-4rwtC:
undetectable		 3a51D-4rwtC:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		5 / 12 ILE C 248
ASN C 185
ILE C 228
ALA C 229
LEU C 269
 None
 1.06A 3a51E-4rwtC:
undetectable		 3a51E-4rwtC:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		5 / 12 ILE C 253
ASN C 217
ILE C 228
ALA C 229
LEU C 269
 None
 1.13A 3a51E-4rwtC:
undetectable		 3a51E-4rwtC:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		5 / 12 THR C 218
ILE C 248
ASN C 185
ILE C 228
LEU C 269
 None
 0.86A 3a51E-4rwtC:
undetectable		 3a51E-4rwtC:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 6 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 1.06A 3abmA-4rwtC:
undetectable
3abmJ-4rwtC:
undetectable		 3abmA-4rwtC:
19.44
3abmJ-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 5 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 1.04A 3ag1J-4rwtC:
undetectable		 3ag1J-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 5 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.93A 3ag2J-4rwtC:
undetectable		 3ag2J-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 5 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 1.06A 3ag4J-4rwtC:
undetectable		 3ag4J-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 6 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 1.03A 3asnA-4rwtC:
undetectable
3asnJ-4rwtC:
undetectable		 3asnA-4rwtC:
19.44
3asnJ-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 8 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.86A 3asnN-4rwtC:
undetectable
3asnW-4rwtC:
undetectable		 3asnN-4rwtC:
19.44
3asnW-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 6 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 1.02A 3asoA-4rwtC:
undetectable
3asoJ-4rwtC:
undetectable		 3asoA-4rwtC:
19.44
3asoJ-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		5 / 11 LEU C 269
ALA C 225
MET C 257
MET C 278
LEU C 290
 None
 1.19A 3bszE-4rwtC:
undetectable		 3bszE-4rwtC:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		5 / 12 ILE C 256
ALA C 259
GLN C 261
ILE C 286
LEU C 260
 None
 1.05A 3dzuA-4rwtC:
undetectable		 3dzuA-4rwtC:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		3 / 3 ASN C 242
ASN C 185
GLU C 183
 None
 0.94A 3kpdB-4rwtC:
undetectable		 3kpdB-4rwtC:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 6 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.80A 3wg7N-4rwtC:
undetectable
3wg7W-4rwtC:
undetectable		 3wg7N-4rwtC:
19.44
3wg7W-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_A_MIYA391_1
(TETX2 PROTEIN)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		5 / 10 PHE C 271
ASN C 273
GLY C 300
GLY C 279
MET C 257
 None
 1.34A 4a99A-4rwtC:
undetectable		 4a99A-4rwtC:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_C_MIYC391_1
(TETX2 PROTEIN)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		5 / 11 PHE C 271
ASN C 273
GLY C 300
GLY C 279
MET C 257
 None
 1.35A 4a99C-4rwtC:
undetectable		 4a99C-4rwtC:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_B_NCAB1536_0
(DIPHTHERIA TOXIN)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 5 HIS C 272
GLY C 300
TYR C 301
GLU C 304
 None
 1.48A 4ae1B-4rwtC:
undetectable		 4ae1B-4rwtC:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 7 ARG C 270
ILE C 256
LEU C 232
THR C 212
 None
 1.04A 4mmcA-4rwtC:
undetectable		 4mmcA-4rwtC:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_A_CL6A502_1
(CYTOCHROME P-450)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 5 LEU C 260
ALA C 255
VAL C 243
ILE C 248
 None
 0.99A 4xe3A-4rwtC:
undetectable		 4xe3A-4rwtC:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 7 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.71A 5b1bA-4rwtC:
undetectable
5b1bJ-4rwtC:
undetectable		 5b1bA-4rwtC:
19.44
5b1bJ-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 7 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.67A 5b1bN-4rwtC:
undetectable
5b1bW-4rwtC:
undetectable		 5b1bN-4rwtC:
19.44
5b1bW-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 7 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.79A 5b3sN-4rwtC:
undetectable
5b3sW-4rwtC:
undetectable		 5b3sN-4rwtC:
19.44
5b3sW-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 7 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.85A 5iy5A-4rwtC:
undetectable
5iy5J-4rwtC:
undetectable		 5iy5A-4rwtC:
19.44
5iy5J-4rwtC:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 5 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.72A 5w97J-4rwtC:
undetectable		 5w97J-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 5 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.99A 5wauJ-4rwtC:
undetectable		 5wauJ-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 5 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 1.18A 5x19J-4rwtC:
undetectable		 5x19J-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 5 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 1.29A 5x1bJ-4rwtC:
undetectable		 5x1bJ-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 5 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 1.16A 5x1bW-4rwtC:
undetectable		 5x1bW-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 6 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 1.09A 5x1fA-4rwtC:
undetectable
5x1fJ-4rwtC:
undetectable		 5x1fA-4rwtC:
19.44
5x1fJ-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 5 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.96A 5x1fW-4rwtC:
undetectable		 5x1fW-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 7 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.64A 5xdqA-4rwtC:
undetectable
5xdqJ-4rwtC:
undetectable		 5xdqA-4rwtC:
19.44
5xdqJ-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 8 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.90A 5xdxN-4rwtC:
undetectable
5xdxW-4rwtC:
undetectable		 5xdxN-4rwtC:
19.44
5xdxW-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 5 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.56A 5z86J-4rwtC:
undetectable		 5z86J-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 6 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.84A 5z86N-4rwtC:
undetectable
5z86W-4rwtC:
undetectable		 5z86N-4rwtC:
19.44
5z86W-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 8 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.56A 5zcoA-4rwtC:
undetectable
5zcoJ-4rwtC:
undetectable		 5zcoA-4rwtC:
19.44
5zcoJ-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 6 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.83A 5zcoN-4rwtC:
undetectable
5zcoW-4rwtC:
undetectable		 5zcoN-4rwtC:
19.44
5zcoW-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 8 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.65A 5zcqN-4rwtC:
undetectable
5zcqW-4rwtC:
undetectable		 5zcqN-4rwtC:
19.44
5zcqW-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 5 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 1.13A 6nknJ-4rwtC:
undetectable		 6nknJ-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4rwt LEIOMODIN-2
(Homo
sapiens) 		4 / 5 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.70A 6nknW-4rwtC:
undetectable		 6nknW-4rwtC:
9.30