SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ry1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		3 / 3 THR A 165
THR A 301
PRO A 303
 None
 0.85A 1a7yA-4ry1A:
undetectable		 1a7yA-4ry1A:
3.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		3 / 3 THR A 165
THR A 301
PRO A 303
 None
 0.88A 1a7yB-4ry1A:
undetectable		 1a7yB-4ry1A:
3.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		3 / 3 THR A 165
THR A 301
PRO A 303
 None
 0.88A 1fjaC-4ry1A:
undetectable		 1fjaC-4ry1A:
3.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		3 / 3 THR A 165
THR A 301
PRO A 303
 None
 0.88A 1fjaD-4ry1A:
undetectable		 1fjaD-4ry1A:
3.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		3 / 3 THR A 165
THR A 301
PRO A 303
 None
 0.80A 1i3wE-4ry1A:
undetectable		 1i3wE-4ry1A:
3.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		3 / 3 THR A 165
THR A 301
PRO A 303
 None
 0.86A 1i3wF-4ry1A:
undetectable		 1i3wF-4ry1A:
3.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		3 / 3 THR A 301
PRO A 303
THR A 165
 None
 0.82A 1i3wG-4ry1A:
undetectable		 1i3wG-4ry1A:
3.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		3 / 3 THR A 165
THR A 301
PRO A 303
 None
 0.86A 1i3wG-4ry1A:
undetectable		 1i3wG-4ry1A:
3.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		3 / 3 THR A 165
THR A 301
PRO A 303
 None
 0.86A 1i3wH-4ry1A:
undetectable		 1i3wH-4ry1A:
3.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		3 / 3 THR A 165
THR A 301
PRO A 303
 None
 0.83A 1mnvD-4ry1A:
undetectable		 1mnvD-4ry1A:
3.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NCW_H_BEZH601_0
(IMMUNOGLOBULIN IGG2A)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		5 / 9 ALA A 376
ASN A 373
LEU A 375
GLY A 352
GLY A 348
 None
 1.39A 1ncwH-4ry1A:
undetectable
1ncwL-4ry1A:
undetectable		 1ncwH-4ry1A:
18.80
1ncwL-4ry1A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		5 / 9 ALA A 376
ASN A 373
LEU A 375
GLY A 352
GLY A 348
 None
 1.43A 1ru9H-4ry1A:
undetectable
1ru9L-4ry1A:
undetectable		 1ru9H-4ry1A:
18.80
1ru9L-4ry1A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUA_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		5 / 10 ALA A 376
ASN A 373
LEU A 375
GLY A 352
GLY A 348
 None
 1.39A 1ruaH-4ry1A:
undetectable
1ruaL-4ry1A:
undetectable		 1ruaH-4ry1A:
18.80
1ruaL-4ry1A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUL_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		5 / 9 ALA A 376
ASN A 373
LEU A 375
GLY A 352
GLY A 348
 None
 1.37A 1rulH-4ry1A:
undetectable
1rulL-4ry1A:
undetectable		 1rulH-4ry1A:
18.80
1rulL-4ry1A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUM_H_BEZH1601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		5 / 9 ALA A 376
ASN A 373
LEU A 375
GLY A 352
GLY A 348
 None
 1.40A 1rumH-4ry1A:
undetectable
1rumL-4ry1A:
undetectable		 1rumH-4ry1A:
18.80
1rumL-4ry1A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUP_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		5 / 9 ALA A 376
ASN A 373
LEU A 375
GLY A 352
GLY A 348
 None
 1.40A 1rupH-4ry1A:
undetectable
1rupL-4ry1A:
undetectable		 1rupH-4ry1A:
18.80
1rupL-4ry1A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		4 / 6 LEU A 139
PHE A 318
ALA A 319
LEU A 117
 None
 1.02A 1ukbA-4ry1A:
undetectable		 1ukbA-4ry1A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		3 / 3 THR A 301
PRO A 303
THR A 165
 None
 0.84A 1unjF-4ry1A:
undetectable		 1unjF-4ry1A:
3.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		3 / 3 THR A 301
PRO A 303
THR A 165
 None
 0.87A 1unjL-4ry1A:
undetectable		 1unjL-4ry1A:
3.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		3 / 3 THR A 301
PRO A 303
THR A 165
 None
 0.87A 1unjR-4ry1A:
undetectable		 1unjR-4ry1A:
3.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		3 / 3 THR A 301
PRO A 303
THR A 165
 None
 0.86A 1unmE-4ry1A:
undetectable		 1unmE-4ry1A:
3.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_1
(CYTOCHROME P450 2C8)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		5 / 12 SER A 316
SER A 315
THR A 144
SER A 279
VAL A 344
 None
GOL  A 501 (-4.4A)
GOL  A 501 ( 4.6A)
GOL  A 501 (-2.8A)
None
 1.26A 2nniA-4ry1A:
undetectable		 2nniA-4ry1A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA801_0
(FERROCHELATASE)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 233
PHE A 234
LEU A 187
VAL A 245
VAL A 196
 None
 1.27A 2qd4A-4ry1A:
undetectable		 2qd4A-4ry1A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA503_0
(CHORISMATE SYNTHASE)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		4 / 5 GLN A 403
THR A 406
ALA A 193
ARG A 257
 None
 1.49A 2qhfA-4ry1A:
undetectable		 2qhfA-4ry1A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		4 / 6 LEU A 409
LEU A 412
ASP A 413
ILE A 199
 None
 1.12A 2rlfB-4ry1A:
undetectable
2rlfC-4ry1A:
undetectable		 2rlfB-4ry1A:
11.38
2rlfC-4ry1A:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		3 / 3 THR A 301
PRO A 303
THR A 165
 None
 0.91A 316dC-4ry1A:
undetectable		 316dC-4ry1A:
3.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		4 / 6 ILE A  61
TRP A  37
ILE A 141
MET A 337
 None
 1.26A 3weoA-4ry1A:
undetectable		 3weoA-4ry1A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		3 / 3 THR A 301
PRO A 303
THR A 165
 None
 0.77A 4hivD-4ry1A:
undetectable		 4hivD-4ry1A:
3.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		5 / 9 THR A 154
GLY A 269
GLY A 181
PHE A 176
LEU A 180
 None
 1.20A 4kqiA-4ry1A:
undetectable		 4kqiA-4ry1A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0U_A_ADNA501_1
(AURORA KINASE A)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		4 / 6 VAL A  89
ALA A 330
LEU A 117
LEU A 110
 None
 0.75A 4o0uA-4ry1A:
undetectable		 4o0uA-4ry1A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		5 / 12 ASP A 248
LEU A 271
PHE A 252
GLY A 192
ASP A 198
 None
 1.20A 4pevC-4ry1A:
2.4		 4pevC-4ry1A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		3 / 3 ARG A 102
THR A 129
TRP A  94
 None
 1.28A 4ug5A-4ry1A:
undetectable		 4ug5A-4ry1A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M10_A_NCAA603_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		4 / 5 LEU A 347
ARG A  91
PHE A 318
LEU A 338
 None
 1.47A 5m10A-4ry1A:
undetectable		 5m10A-4ry1A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		3 / 3 GLY A 343
THR A 144
PRO A 354
 None
GOL  A 501 ( 4.6A)
None
 0.63A 5v5zA-4ry1A:
undetectable		 5v5zA-4ry1A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_1
(STIE PROTEIN)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		4 / 5 THR A 201
THR A 301
GLN A 209
ASP A 167
 None
None
GOL  A 503 ( 4.6A)
None
 1.44A 6ectA-4ry1A:
undetectable		 6ectA-4ry1A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_1
(STIE PROTEIN)		 4ry1 PERIPLASMIC SOLUTE
BINDING PROTEIN
(Pectobacterium
atrosepticum) 		4 / 5 THR A 201
THR A 301
GLN A 209
ASP A 167
 None
None
GOL  A 503 ( 4.6A)
None
 1.50A 6ecxA-4ry1A:
undetectable		 6ecxA-4ry1A:
24.53