SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ryi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 4ryi INTEGRAL MEMBRANE
PROTEIN
(Bacillus
cereus) 		3 / 3 ASP A 106
LEU A  82
LEU A 109
 None
 0.64A 1ikeA-4ryiA:
undetectable		 1ikeA-4ryiA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 4ryi INTEGRAL MEMBRANE
PROTEIN
(Bacillus
cereus) 		4 / 8 PHE A 120
SER A 121
LEU A 124
ILE A  65
 None
 0.95A 1sbrA-4ryiA:
undetectable		 1sbrA-4ryiA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 4ryi INTEGRAL MEMBRANE
PROTEIN
(Bacillus
cereus) 		3 / 3 PHE A  55
SER A  21
SER A  22
 PKA  A 201 (-4.9A)
PKA  A 201 ( 4.0A)
PKA  A 201 (-2.9A)
 0.93A 3ufgB-4ryiA:
2.7		 3ufgB-4ryiA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4ryi INTEGRAL MEMBRANE
PROTEIN
(Bacillus
cereus) 		3 / 3 SER A  22
SER A  91
PHE A  55
 PKA  A 201 (-2.9A)
PKA  A 201 (-2.9A)
PKA  A 201 (-4.9A)
 0.93A 5mugA-4ryiA:
undetectable		 5mugA-4ryiA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 4ryi INTEGRAL MEMBRANE
PROTEIN
(Bacillus
cereus) 		3 / 3 TYR A 144
SER A 146
TRP A  40
 None
PKA  A 201 ( 4.4A)
None
 1.03A 5n8jB-4ryiA:
undetectable		 5n8jB-4ryiA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 4ryi INTEGRAL MEMBRANE
PROTEIN
(Bacillus
cereus) 		3 / 3 TYR A 144
SER A 146
TRP A  40
 None
PKA  A 201 ( 4.4A)
None
 1.01A 5n8jA-4ryiA:
undetectable		 5n8jA-4ryiA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 4ryi INTEGRAL MEMBRANE
PROTEIN
(Bacillus
cereus) 		3 / 3 TYR A 144
SER A 146
TRP A  40
 None
PKA  A 201 ( 4.4A)
None
 1.02A 5n8jD-4ryiA:
undetectable		 5n8jD-4ryiA:
18.41