SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ryk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4ryk LMO0325 PROTEIN
(Listeria
monocytogenes) 		4 / 7 LEU A 224
MET A 180
TYR A 184
LEU A 200
 None
 1.11A 1kt3A-4rykA:
undetectable		 1kt3A-4rykA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 4ryk LMO0325 PROTEIN
(Listeria
monocytogenes) 		5 / 11 ILE A  54
LEU A  51
TYR A  23
ARG A   9
GLY A   5
 None
 1.19A 2bxmA-4rykA:
2.5		 2bxmA-4rykA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 4ryk LMO0325 PROTEIN
(Listeria
monocytogenes) 		4 / 6 PHE A  61
TYR A  23
ARG A   9
GLY A   5
 None
 1.14A 2i30A-4rykA:
3.2		 2i30A-4rykA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 4ryk LMO0325 PROTEIN
(Listeria
monocytogenes) 		4 / 5 ILE A  54
TYR A  23
ARG A   9
GLY A   5
 None
 1.01A 3b9mA-4rykA:
3.2		 3b9mA-4rykA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 4ryk LMO0325 PROTEIN
(Listeria
monocytogenes) 		3 / 3 CYH A 198
PHE A 197
PHE A 201
 None
 0.97A 3cr5X-4rykA:
undetectable		 3cr5X-4rykA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 4ryk LMO0325 PROTEIN
(Listeria
monocytogenes) 		4 / 7 GLU A 185
GLU A 226
TYR A 189
TYR A 184
 None
None
TLA  A 402 (-3.6A)
None
 1.04A 3ku9B-4rykA:
undetectable		 3ku9B-4rykA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 4ryk LMO0325 PROTEIN
(Listeria
monocytogenes) 		4 / 8 LEU A 181
LEU A 200
THR A 205
GLN A 247
 None
 1.03A 5hbsA-4rykA:
undetectable		 5hbsA-4rykA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 4ryk LMO0325 PROTEIN
(Listeria
monocytogenes) 		4 / 8 LEU A 181
LEU A 200
ILE A 250
GLN A 247
 None
 1.04A 5ljbA-4rykA:
undetectable		 5ljbA-4rykA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 4ryk LMO0325 PROTEIN
(Listeria
monocytogenes) 		4 / 8 LEU A 181
LEU A 200
THR A 205
GLN A 247
 None
 0.99A 5ljbA-4rykA:
undetectable		 5ljbA-4rykA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4ryk LMO0325 PROTEIN
(Listeria
monocytogenes) 		4 / 6 ILE A 118
ILE A 160
PHE A  80
PHE A 176
 None
 0.69A 5vkqA-4rykA:
2.2
5vkqB-4rykA:
2.3		 5vkqA-4rykA:
10.76
5vkqB-4rykA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4ryk LMO0325 PROTEIN
(Listeria
monocytogenes) 		4 / 6 PHE A 176
ILE A 118
ILE A 160
PHE A  80
 None
 0.65A 5vkqA-4rykA:
2.2
5vkqD-4rykA:
2.2		 5vkqA-4rykA:
10.76
5vkqD-4rykA:
10.76