SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4s13'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4003_1
(SERUM ALBUMIN)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 9 PHE A  53
VAL A 316
GLY A  68
CYH A  69
LEU A 144
 None
 1.17A 1e7bA-4s13A:
undetectable		 1e7bA-4s13A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_A_ESTA351_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 VAL A  36
GLY A  37
LEU A 144
PRO A  32
LEU A 153
 None
 1.06A 1fduA-4s13A:
undetectable		 1fduA-4s13A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		4 / 7 SER A 447
PHE A 291
ALA A 443
PHE A 440
 None
 1.13A 1fxvA-4s13A:
undetectable
1fxvB-4s13A:
undetectable		 1fxvA-4s13A:
17.60
1fxvB-4s13A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		4 / 4 GLY A 186
LEU A 187
GLY A 176
ARG A 175
 None
 1.27A 1j7kA-4s13A:
undetectable		 1j7kA-4s13A:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  84
GLY A  82
THR A 328
LEU A 329
ASP A  22
 None
 0.87A 1liiA-4s13A:
undetectable		 1liiA-4s13A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 335
SER A 332
TYR A 390
ASP A 351
ILE A 349
 None
 1.20A 1nt2A-4s13A:
undetectable		 1nt2A-4s13A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 212
ALA A 213
LEU A 214
CYH A 124
 None
 0.88A 1sbrA-4s13A:
undetectable
1sbrB-4s13A:
undetectable		 1sbrA-4s13A:
17.36
1sbrB-4s13A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 11 GLY A  72
LEU A 329
HIS A  87
HIS A  86
ALA A  50
 None
 1.39A 2a58A-4s13A:
undetectable
2a58E-4s13A:
undetectable		 2a58A-4s13A:
16.00
2a58E-4s13A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 11 HIS A  86
ALA A  50
GLY A  72
LEU A 329
HIS A  87
 None
 1.40A 2a58C-4s13A:
undetectable
2a58D-4s13A:
undetectable		 2a58C-4s13A:
16.00
2a58D-4s13A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 PHE A  53
VAL A 316
GLY A  68
CYH A  69
LEU A 144
 None
 1.22A 2bxeB-4s13A:
undetectable		 2bxeB-4s13A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 347
VAL A 395
GLY A 396
ALA A 338
LEU A 341
 None
 1.14A 2bxgA-4s13A:
undetectable		 2bxgA-4s13A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 341
LEU A 333
MET A 228
 None
None
4VP  A 601 ( 3.7A)
 0.62A 2itzA-4s13A:
undetectable		 2itzA-4s13A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 368
ILE A 465
ASN A 463
PHE A 382
 None
 1.16A 2jc9A-4s13A:
undetectable		 2jc9A-4s13A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		4 / 7 ASN A 463
LEU A 404
TYR A 470
VAL A 367
 None
 1.15A 2uz2A-4s13A:
undetectable		 2uz2A-4s13A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_B_TMQB612_1
(DHFR-TS)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 465
ASP A 408
ILE A 349
PRO A 348
ILE A 411
 None
 1.22A 3clbB-4s13A:
undetectable		 3clbB-4s13A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		3 / 3 SER A 172
GLU A 280
ASP A 148
 None
 0.79A 3dmhA-4s13A:
undetectable		 3dmhA-4s13A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  88
GLY A  89
LEU A  90
ILE A  99
ASP A  80
 None
 1.09A 3gwwA-4s13A:
undetectable		 3gwwA-4s13A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_B_ECNB411_1
(FLAVOHEMOGLOBIN)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 9 ILE A  84
ILE A  96
ALA A 335
LEU A  88
ALA A  85
 None
 1.10A 3ozvB-4s13A:
undetectable		 3ozvB-4s13A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		4 / 6 HIS A 127
GLU A 265
ASP A  12
ASP A 310
 None
 0.97A 3vywA-4s13A:
undetectable		 3vywA-4s13A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  84
GLY A  82
THR A 328
LEU A 329
ASP A  22
 None
 0.96A 4e3aA-4s13A:
undetectable		 4e3aA-4s13A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 408
ASN A 480
CYH A 479
GLU A 416
 None
 1.18A 4fewD-4s13A:
undetectable		 4fewD-4s13A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 408
ASN A 480
CYH A 479
GLU A 416
 None
 1.16A 4fewF-4s13A:
undetectable		 4fewF-4s13A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 408
ASN A 480
CYH A 479
GLU A 416
 None
 1.15A 4gkhB-4s13A:
undetectable		 4gkhB-4s13A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  84
GLY A  82
THR A 328
LEU A 329
ASP A  22
 None
 0.97A 4jkuB-4s13A:
undetectable		 4jkuB-4s13A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  84
GLY A  82
THR A 328
LEU A 329
ASP A  22
 None
 0.95A 4k8pA-4s13A:
undetectable		 4k8pA-4s13A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  84
GLY A  82
THR A 328
LEU A 329
ASP A  22
 None
 0.96A 4k8pB-4s13A:
undetectable		 4k8pB-4s13A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  84
GLY A  82
THR A 328
LEU A 329
ASP A  22
 None
 0.94A 4k8tA-4s13A:
undetectable		 4k8tA-4s13A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  84
GLY A  82
THR A 328
LEU A 329
ASP A  22
 None
 0.94A 4k8tB-4s13A:
undetectable		 4k8tB-4s13A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  84
GLY A  82
THR A 328
LEU A 329
ASP A  22
 None
 0.95A 4k93A-4s13A:
undetectable		 4k93A-4s13A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  84
GLY A  82
THR A 328
LEU A 329
ASP A  22
 None
 0.94A 4k93B-4s13A:
undetectable		 4k93B-4s13A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  84
GLY A  82
THR A 328
LEU A 329
ASP A  22
 None
 0.96A 4k9cA-4s13A:
undetectable		 4k9cA-4s13A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  84
GLY A  82
THR A 328
LEU A 329
ASP A  22
 None
 0.96A 4k9cB-4s13A:
undetectable		 4k9cB-4s13A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  84
GLY A  82
THR A 328
LEU A 329
ASP A  22
 None
 0.93A 4k9iA-4s13A:
undetectable		 4k9iA-4s13A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  84
GLY A  82
THR A 328
LEU A 329
ASP A  22
 None
 0.95A 4k9iB-4s13A:
undetectable		 4k9iB-4s13A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  84
GLY A  82
THR A 328
LEU A 329
ASP A  22
 None
 0.96A 4kadA-4s13A:
undetectable		 4kadA-4s13A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  84
GLY A  82
THR A 328
LEU A 329
ASP A  22
 None
 0.94A 4lbxA-4s13A:
undetectable		 4lbxA-4s13A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  84
GLY A  82
THR A 328
LEU A 329
ASP A  22
 None
 0.93A 4lbxB-4s13A:
undetectable		 4lbxB-4s13A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  84
GLY A  82
THR A 328
LEU A 329
ASP A  22
 None
 0.94A 4lc4A-4s13A:
undetectable		 4lc4A-4s13A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  84
GLY A  82
THR A 328
LEU A 329
ASP A  22
 None
 0.95A 4lc4B-4s13A:
undetectable		 4lc4B-4s13A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 PHE A  64
VAL A 178
GLY A 157
PHE A 268
THR A 155
 None
 1.36A 4mubA-4s13A:
undetectable		 4mubA-4s13A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA601_1
(SERUM ALBUMIN)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 11 PHE A  53
VAL A 316
GLY A  68
CYH A  69
LEU A 144
 None
 1.16A 4or0A-4s13A:
undetectable		 4or0A-4s13A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 PHE A  53
VAL A 316
GLY A  68
CYH A  69
LEU A 144
 None
 1.24A 4ot2A-4s13A:
undetectable		 4ot2A-4s13A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 HIS A  87
SER A 227
GLY A 217
PHE A  13
GLY A  68
 None
 1.36A 4uinH-4s13A:
undetectable
4uinL-4s13A:
undetectable		 4uinH-4s13A:
17.86
4uinL-4s13A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		4 / 8 SER A  60
LEU A  63
ASP A  62
ASP A 310
 None
 1.02A 4umjA-4s13A:
undetectable		 4umjA-4s13A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_A_GBMA801_1
(PROLINE--TRNA LIGASE)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 314
THR A 155
ARG A 175
GLY A 176
ILE A 184
 None
 1.19A 5ifuA-4s13A:
undetectable		 5ifuA-4s13A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSA_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		4 / 4 TYR A 156
SER A 317
GLU A 285
ASP A 324
 None
None
4VP  A 601 (-2.3A)
None
 1.43A 5lsaA-4s13A:
undetectable		 5lsaA-4s13A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 TYR A 356
HIS A  81
ASP A 324
PRO A 319
GLU A 285
 None
None
None
None
4VP  A 601 (-2.3A)
 1.22A 5x6yC-4s13A:
undetectable		 5x6yC-4s13A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		5 / 12 PHE A  53
VAL A 316
GLY A  68
CYH A  69
LEU A 144
 None
 1.28A 6ci6A-4s13A:
undetectable		 6ci6A-4s13A:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		4 / 6 TYR A 476
ASP A 407
GLN A 373
THR A 478
 None
 1.28A 6djzA-4s13A:
undetectable		 6djzA-4s13A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_D_AM2D301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4s13 FERULIC ACID
DECARBOXYLASE 1
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 310
ARG A 309
HIS A 127
GLU A 265
 None
 1.21A 6mn4D-4s13A:
undetectable		 6mn4D-4s13A:
21.60