SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4s1p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 4s1p UNCHARACTERIZED
PROTEIN
(Slackia
heliotrinireduce
ns) 		5 / 11 TYR A  80
THR A 103
LEU A  38
GLY A   7
THR A  11
 None
 1.20A 1akdA-4s1pA:
undetectable		 1akdA-4s1pA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 4s1p UNCHARACTERIZED
PROTEIN
(Slackia
heliotrinireduce
ns) 		5 / 11 PHE A 131
THR A 103
LEU A  38
GLY A   7
THR A  11
 None
 1.04A 1phgA-4s1pA:
undetectable		 1phgA-4s1pA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 4s1p UNCHARACTERIZED
PROTEIN
(Slackia
heliotrinireduce
ns) 		5 / 11 TYR A  80
THR A 103
LEU A  38
GLY A   7
THR A  11
 None
 1.11A 1phgA-4s1pA:
undetectable		 1phgA-4s1pA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4s1p UNCHARACTERIZED
PROTEIN
(Slackia
heliotrinireduce
ns) 		5 / 11 TYR A  80
THR A 103
LEU A  38
GLY A   7
THR A  11
 None
 1.26A 2a1nA-4s1pA:
undetectable		 2a1nA-4s1pA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1437_1
(ORF12)		 4s1p UNCHARACTERIZED
PROTEIN
(Slackia
heliotrinireduce
ns) 		5 / 11 SER A 138
SER A  88
ALA A 140
GLY A 139
ALA A 135
 None
 1.50A 2xh9A-4s1pA:
undetectable		 2xh9A-4s1pA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_0
(HYPOTHETICAL PROTEIN)		 4s1p UNCHARACTERIZED
PROTEIN
(Slackia
heliotrinireduce
ns) 		5 / 12 GLY A 169
SER A 170
ALA A 174
LEU A 175
ALA A 154
 None
 1.15A 2yvlC-4s1pA:
3.8		 2yvlC-4s1pA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 4s1p UNCHARACTERIZED
PROTEIN
(Slackia
heliotrinireduce
ns) 		5 / 11 TYR A  80
THR A 103
LEU A  38
GLY A   7
THR A  11
 None
 1.11A 3lxiB-4s1pA:
undetectable		 3lxiB-4s1pA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_A_CAMA424_0
(CYTOCHROME P450)		 4s1p UNCHARACTERIZED
PROTEIN
(Slackia
heliotrinireduce
ns) 		5 / 9 TYR A  80
THR A 103
LEU A  38
GLY A   7
THR A  11
 None
 1.10A 4c9kA-4s1pA:
undetectable		 4c9kA-4s1pA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 4s1p UNCHARACTERIZED
PROTEIN
(Slackia
heliotrinireduce
ns) 		5 / 9 TYR A  80
THR A 103
LEU A  38
GLY A   7
THR A  11
 None
 1.10A 4c9kB-4s1pA:
undetectable		 4c9kB-4s1pA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_A_GAIA407_0
(PROTEIN (ARGINASE))		 4s1p UNCHARACTERIZED
PROTEIN
(Slackia
heliotrinireduce
ns) 		4 / 6 ARG A 126
LEU A 113
MET A 118
ASP A 122
 None
 1.29A 4cevA-4s1pA:
2.9
4cevB-4s1pA:
3.0		 4cevA-4s1pA:
20.93
4cevB-4s1pA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_C_GAIC409_0
(PROTEIN (ARGINASE))		 4s1p UNCHARACTERIZED
PROTEIN
(Slackia
heliotrinireduce
ns) 		4 / 6 MET A 118
ASP A 122
ARG A 126
LEU A 113
 None
 1.29A 4cevA-4s1pA:
3.0
4cevC-4s1pA:
2.9		 4cevA-4s1pA:
20.93
4cevC-4s1pA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_D_GAID410_0
(PROTEIN (ARGINASE))		 4s1p UNCHARACTERIZED
PROTEIN
(Slackia
heliotrinireduce
ns) 		4 / 6 ARG A 126
LEU A 113
MET A 118
ASP A 122
 None
 1.26A 4cevD-4s1pA:
2.9
4cevE-4s1pA:
3.0		 4cevD-4s1pA:
20.93
4cevE-4s1pA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF411_0
(PROTEIN (ARGINASE))		 4s1p UNCHARACTERIZED
PROTEIN
(Slackia
heliotrinireduce
ns) 		4 / 6 ARG A 126
LEU A 113
MET A 118
ASP A 122
 None
 1.31A 4cevE-4s1pA:
3.3
4cevF-4s1pA:
3.5		 4cevE-4s1pA:
20.93
4cevF-4s1pA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4s1p UNCHARACTERIZED
PROTEIN
(Slackia
heliotrinireduce
ns) 		5 / 12 HIS A 164
ASP A 161
LEU A  10
ASN A   8
GLY A  34
 UNL  A 501 ( 4.1A)
None
None
UNL  A 501 ( 3.1A)
UNL  A 501 ( 3.4A)
 1.27A 4pgfA-4s1pA:
5.3		 4pgfA-4s1pA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 4s1p UNCHARACTERIZED
PROTEIN
(Slackia
heliotrinireduce
ns) 		5 / 9 TYR A  80
THR A 103
LEU A  38
GLY A   7
THR A  11
 None
 1.16A 5cp4A-4s1pA:
undetectable		 5cp4A-4s1pA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4s1p UNCHARACTERIZED
PROTEIN
(Slackia
heliotrinireduce
ns) 		3 / 3 THR A  12
PRO A  17
ASP A  18
 None
 0.91A 5l8dB-4s1pA:
undetectable		 5l8dB-4s1pA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4s1p UNCHARACTERIZED
PROTEIN
(Slackia
heliotrinireduce
ns) 		3 / 3 THR A  12
PRO A  17
ASP A  18
 None
 0.91A 5mwuB-4s1pA:
undetectable		 5mwuB-4s1pA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 4s1p UNCHARACTERIZED
PROTEIN
(Slackia
heliotrinireduce
ns) 		5 / 9 ALA A 168
SER A 166
ALA A 154
SER A 153
GLY A 152
 None
 1.10A 6bklE-4s1pA:
undetectable
6bklF-4s1pA:
undetectable
6bklG-4s1pA:
undetectable
6bklH-4s1pA:
undetectable		 6bklE-4s1pA:
7.95
6bklF-4s1pA:
7.95
6bklG-4s1pA:
7.95
6bklH-4s1pA:
7.95