SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4s1v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU D 247
ALA D 116
ALA D 259
LEU D 207
TYR D 264
 None
 1.24A 1kt5A-4s1vD:
undetectable		 1kt5A-4s1vD:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		5 / 10 LEU D 247
ALA D 116
ALA D 259
VAL D 242
LEU D 207
 None
 1.32A 1rlbE-4s1vD:
undetectable		 1rlbE-4s1vD:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_F_REAF177_1
(RETINOL BINDING
PROTEIN)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		5 / 11 LEU D 247
ALA D 116
ALA D 259
VAL D 242
LEU D 207
 None
 1.17A 1rlbF-4s1vD:
undetectable		 1rlbF-4s1vD:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_A_STRA301_1
(MINERALOCORTICOID
RECEPTOR)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		5 / 12 ALA D 202
MET D 227
SER D 231
LEU D 232
ARG D 142
 None
 1.30A 2aa5A-4s1vD:
undetectable		 2aa5A-4s1vD:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		5 / 12 ALA D 202
MET D 227
SER D 231
LEU D 232
ARG D 142
 None
 1.31A 2aa5B-4s1vD:
undetectable		 2aa5B-4s1vD:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		4 / 5 VAL D 234
SER D 237
VAL D 263
SER D 206
 None
 1.14A 2j9cA-4s1vD:
undetectable
2j9cB-4s1vD:
undetectable
2j9cC-4s1vD:
undetectable		 2j9cA-4s1vD:
17.52
2j9cB-4s1vD:
17.52
2j9cC-4s1vD:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2001_1
(SERUM ALBUMIN)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		5 / 12 ILE D 151
HIS D 208
TYR D 189
ARG D 160
GLY D 155
 None
 1.38A 2vufA-4s1vD:
undetectable		 2vufA-4s1vD:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2001_1
(SERUM ALBUMIN)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		5 / 12 ILE D 151
HIS D 208
TYR D 189
ARG D 160
GLY D 155
 None
 1.32A 2vufB-4s1vD:
undetectable		 2vufB-4s1vD:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		5 / 10 ILE D 172
ILE D 151
GLY D 155
PRO D 102
LEU D 187
 None
 1.08A 3elzB-4s1vD:
undetectable		 3elzB-4s1vD:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		5 / 10 ILE D 172
ILE D 151
GLY D 155
PRO D 102
LEU D 187
 None
 0.99A 3elzC-4s1vD:
undetectable		 3elzC-4s1vD:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU D 149
ALA D 202
LEU D 232
ARG D 142
ILE D 161
 None
 1.31A 3olsB-4s1vD:
undetectable		 3olsB-4s1vD:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		4 / 6 GLU D 274
GLU D 267
GLU D 265
GLU D 240
 None
 1.25A 4mi4A-4s1vD:
undetectable		 4mi4A-4s1vD:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		4 / 7 GLU D 274
GLU D 267
GLU D 265
GLU D 240
 None
 1.22A 4mi4A-4s1vD:
undetectable
4mi4C-4s1vD:
undetectable		 4mi4A-4s1vD:
21.75
4mi4C-4s1vD:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		4 / 7 GLU D 274
GLU D 267
GLU D 265
GLU D 240
 None
 1.24A 4mj8C-4s1vD:
undetectable		 4mj8C-4s1vD:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		4 / 7 GLU D 274
GLU D 267
GLU D 265
GLU D 240
 None
 1.29A 4r87I-4s1vD:
undetectable		 4r87I-4s1vD:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		3 / 3 MET D   1
GLU D  48
LEU D  72
 None
 0.79A 4v2oB-4s1vD:
undetectable		 4v2oB-4s1vD:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_B_SAMB601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		5 / 12 ASP D  84
LEU D  87
ILE D  59
VAL D  95
VAL D  93
 None
 1.08A 5dpdB-4s1vD:
5.5		 5dpdB-4s1vD:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		4 / 5 HIS D 312
HIS D  25
VAL D 308
ALA D 311
 None
 1.12A 5i3bB-4s1vD:
undetectable		 5i3bB-4s1vD:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		5 / 9 SER D 177
GLY D 176
ALA D 184
LEU D 154
GLY D 153
 None
 1.29A 5l8rA-4s1vD:
undetectable		 5l8rA-4s1vD:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU D 277
LEU D 270
ALA D 269
LEU D 108
LEU D 112
 None
 1.06A 5ljeA-4s1vD:
undetectable		 5ljeA-4s1vD:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_A_SAMA501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		5 / 12 ALA D 106
PRO D 105
GLY D 289
GLY D 165
LEU D 149
 None
 1.07A 5wwsA-4s1vD:
5.4		 5wwsA-4s1vD:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		4 / 7 HIS D  82
THR D  76
TYR D 299
LEU D  16
 None
 1.19A 5x1fA-4s1vD:
undetectable
5x1fC-4s1vD:
undetectable
5x1fP-4s1vD:
undetectable		 5x1fA-4s1vD:
20.39
5x1fC-4s1vD:
21.84
5x1fP-4s1vD:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)		 4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN
(Vibrio
cholerae) 		3 / 3 TYR D   9
ASP D  32
ASP D   7
 None
 0.85A 5x6yA-4s1vD:
1.8		 5x6yA-4s1vD:
17.35