SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4s24'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Y7I_A_SALA502_1 (SALICYLIC ACID-BINDING PROTEIN 2)	4s24	MODULATOR OF DRUG ACTIVITY B (Yersinia pestis)	3 / 3	LEU A 149 HIS A 152 LYS A 153	None PEG A 203 ( 4.2A) None	0.89A	1y7iA-4s24A: 2.3	1y7iA-4s24A: 23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QE6_A_SAMA400_1 (UNCHARACTERIZED PROTEIN TFU_2867)	4s24	MODULATOR OF DRUG ACTIVITY B (Yersinia pestis)	3 / 3	ASN A 169 ARG A 129 ASP A 145	None None PEG A 203 (-3.2A)	0.89A	2qe6A-4s24A: undetectable	2qe6A-4s24A: 20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QE6_B_SAMB400_1 (UNCHARACTERIZED PROTEIN TFU_2867)	4s24	MODULATOR OF DRUG ACTIVITY B (Yersinia pestis)	3 / 3	ASN A 169 ARG A 129 ASP A 145	None None PEG A 203 (-3.2A)	0.91A	2qe6B-4s24A: undetectable	2qe6B-4s24A: 20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IW1_A_ASDA1223_1 (CYTOCHROME P450 CYP125)	4s24	MODULATOR OF DRUG ACTIVITY B (Yersinia pestis)	5 / 12	ILE A 177 PHE A 31 VAL A 27 SER A 122 ILE A 64	None	1.17A	3iw1A-4s24A: undetectable	3iw1A-4s24A: 16.67

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1Y7I_A_SALA502_1","SALICYLIC ACID-BINDING PROTEIN 2","4s24","MODULATOR OF DRUG ACTIVITY B","Yersinia pestis",3,"LEU A 149;HIS A 152;LYS A 153","None;PEG A 203 ( 4.2A);None","0.89A","1y7iA-4s24A:2.3","1y7iA-4s24A:23.88"],["2QE6_A_SAMA400_1","UNCHARACTERIZED PROTEIN TFU_2867","4s24","MODULATOR OF DRUG ACTIVITY B","Yersinia pestis",3,"ASN A 169;ARG A 129;ASP A 145","None;None;PEG A 203 (-3.2A)","0.89A","2qe6A-4s24A:undetectable","2qe6A-4s24A:20.52"],["2QE6_B_SAMB400_1","UNCHARACTERIZED PROTEIN TFU_2867","4s24","MODULATOR OF DRUG ACTIVITY B","Yersinia pestis",3,"ASN A 169;ARG A 129;ASP A 145","None;None;PEG A 203 (-3.2A)","0.91A","2qe6B-4s24A:undetectable","2qe6B-4s24A:20.52"],["3IW1_A_ASDA1223_1","CYTOCHROME P450 CYP125","4s24","MODULATOR OF DRUG ACTIVITY B","Yersinia pestis",5,"ILE A 177;PHE A  31;VAL A  27;SER A 122;ILE A  64","None","1.17A","3iw1A-4s24A:undetectable","3iw1A-4s24A:16.67"]]