SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4s3j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 162
THR A 166
PRO A 168
 None
 0.83A 1a7yA-4s3jA:
undetectable		 1a7yA-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 162
THR A 166
PRO A 168
 None
 0.82A 1a7yB-4s3jA:
undetectable		 1a7yB-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DBB_H_STRH229_1
(IGG1-KAPPA DB3 FAB
(HEAVY CHAIN)
IGG1-KAPPA DB3 FAB
(LIGHT CHAIN))		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		4 / 8 GLY A 290
TRP A 328
GLY A 289
VAL A 342
 None
 0.87A 1dbbH-4s3jA:
undetectable
1dbbL-4s3jA:
undetectable		 1dbbH-4s3jA:
21.51
1dbbL-4s3jA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		5 / 9 PHE A 138
ASP A 217
MET A 281
TYR A 283
ASP A 284
 None
 1.01A 1e9lA-4s3jA:
31.2		 1e9lA-4s3jA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		5 / 9 TYR A 109
ASP A 217
MET A 281
TYR A 283
ASP A 284
 None
 0.81A 1e9lA-4s3jA:
31.2		 1e9lA-4s3jA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 162
THR A 166
PRO A 168
 None
 0.89A 1fjaC-4s3jA:
undetectable		 1fjaC-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 162
THR A 166
PRO A 168
 None
 0.89A 1fjaD-4s3jA:
undetectable		 1fjaD-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 162
THR A 166
PRO A 168
 None
 0.79A 1i3wE-4s3jA:
undetectable		 1i3wE-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 162
THR A 166
PRO A 168
 None
 0.85A 1i3wF-4s3jA:
undetectable		 1i3wF-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 166
PRO A 168
THR A 162
 None
 0.81A 1i3wG-4s3jA:
undetectable		 1i3wG-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 162
THR A 166
PRO A 168
 None
 0.87A 1i3wG-4s3jA:
undetectable		 1i3wG-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 162
THR A 166
PRO A 168
 None
 0.84A 1i3wH-4s3jA:
undetectable		 1i3wH-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 166
PRO A 168
THR A 162
 None
 0.85A 1mnvD-4s3jA:
undetectable		 1mnvD-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 162
THR A 166
PRO A 168
 None
 0.84A 1qfiA-4s3jA:
undetectable		 1qfiA-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 162
THR A 166
PRO A 168
 None
 0.82A 1qfiB-4s3jA:
undetectable		 1qfiB-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		4 / 7 TYR A 109
THR A 245
SER A 247
VAL A 279
 None
 0.85A 1tv8A-4s3jA:
3.3		 1tv8A-4s3jA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 166
PRO A 168
THR A 162
 None
 0.81A 1unjF-4s3jA:
undetectable		 1unjF-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 166
PRO A 168
THR A 162
 None
 0.84A 1unjL-4s3jA:
undetectable		 1unjL-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 162
THR A 166
PRO A 168
 None
 0.85A 1unjL-4s3jA:
undetectable		 1unjL-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 166
PRO A 168
THR A 162
 None
 0.84A 1unjR-4s3jA:
undetectable		 1unjR-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 162
THR A 166
PRO A 168
 None
 0.86A 1unjW-4s3jA:
undetectable		 1unjW-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 166
PRO A 168
THR A 162
 None
 0.85A 1unjX-4s3jA:
undetectable		 1unjX-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 162
THR A 166
PRO A 168
 None
 0.86A 1unjX-4s3jA:
undetectable		 1unjX-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 166
PRO A 168
THR A 162
 None
 0.82A 1unmE-4s3jA:
undetectable		 1unmE-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		6 / 11 TYR A 109
GLU A 219
MET A 281
TYR A 283
TYR A 324
TRP A 407
 None
 0.68A 2a3aA-4s3jA:
29.8		 2a3aA-4s3jA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		6 / 11 TYR A 109
MET A 281
TYR A 283
ASP A 284
TYR A 324
TRP A 407
 None
 0.68A 2a3aA-4s3jA:
29.8		 2a3aA-4s3jA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		6 / 9 PHE A 138
GLU A 219
MET A 281
TYR A 283
TYR A 324
TRP A 407
 None
 0.94A 2a3aB-4s3jA:
29.9		 2a3aB-4s3jA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		6 / 9 PHE A 138
MET A 281
TYR A 283
ASP A 284
TYR A 324
TRP A 407
 None
 0.81A 2a3aB-4s3jA:
29.9		 2a3aB-4s3jA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		6 / 10 ASP A 217
GLU A 219
MET A 281
TYR A 283
TYR A 324
TRP A 407
 None
 1.05A 2a3bB-4s3jA:
30.0		 2a3bB-4s3jA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		6 / 10 ASP A 217
MET A 281
TYR A 283
ASP A 284
TYR A 324
TRP A 407
 None
 0.82A 2a3bB-4s3jA:
30.0		 2a3bB-4s3jA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		6 / 10 PHE A 138
ASP A 217
GLU A 219
MET A 281
TYR A 283
TYR A 324
 None
 1.28A 2a3bB-4s3jA:
30.0		 2a3bB-4s3jA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		6 / 10 PHE A 138
ASP A 217
MET A 281
TYR A 283
ASP A 284
TYR A 324
 None
 1.11A 2a3bB-4s3jA:
30.0		 2a3bB-4s3jA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		6 / 12 ASP A 217
GLU A 219
MET A 281
TYR A 283
TYR A 324
TRP A 407
 None
 1.06A 2a3cB-4s3jA:
30.0		 2a3cB-4s3jA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		6 / 12 ASP A 217
MET A 281
TYR A 283
ASP A 284
TYR A 324
TRP A 407
 None
 0.84A 2a3cB-4s3jA:
30.0		 2a3cB-4s3jA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		6 / 12 PHE A 138
ASP A 217
GLU A 219
MET A 281
TYR A 283
TYR A 324
 None
 1.29A 2a3cB-4s3jA:
30.0		 2a3cB-4s3jA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		6 / 12 PHE A 138
ASP A 217
MET A 281
TYR A 283
ASP A 284
TYR A 324
 None
 1.13A 2a3cB-4s3jA:
30.0		 2a3cB-4s3jA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		4 / 8 TYR A 109
THR A 245
SER A 247
VAL A 279
 None
 0.92A 2fb2A-4s3jA:
3.5		 2fb2A-4s3jA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		4 / 7 TYR A 109
THR A 245
SER A 247
VAL A 279
 None
 0.94A 2fb2B-4s3jA:
3.2		 2fb2B-4s3jA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		4 / 6 LEU A 110
TYR A 137
ILE A 160
ILE A 117
 None
 0.97A 2q8hA-4s3jA:
undetectable		 2q8hA-4s3jA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		6 / 9 TYR A 109
PHE A 138
ASP A 217
GLU A 219
TYR A 283
TRP A 407
 None
 1.14A 2uy4A-4s3jA:
16.7		 2uy4A-4s3jA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 TRP A 328
GLN A 334
TRP A 285
 None
 1.40A 2vqyA-4s3jA:
undetectable		 2vqyA-4s3jA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 166
PRO A 168
THR A 162
 None
 0.90A 316dC-4s3jA:
undetectable		 316dC-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 SER A 391
GLN A 390
PHE A 393
 None
 0.80A 3g4lC-4s3jA:
undetectable		 3g4lC-4s3jA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		6 / 11 ASP A 217
MET A 281
TYR A 283
ASP A 284
TYR A 324
TRP A 407
 None
 0.85A 3g6mA-4s3jA:
30.2		 3g6mA-4s3jA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		6 / 11 TYR A 109
MET A 281
TYR A 283
ASP A 284
TYR A 324
TRP A 407
 None
 0.73A 3g6mA-4s3jA:
30.2		 3g6mA-4s3jA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_I_P77I203_1
(PROTEIN S100-A4)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		5 / 10 LEU A 203
ILE A 199
PHE A 140
ASP A 213
PHE A 216
 None
 1.45A 3m0wA-4s3jA:
undetectable
3m0wB-4s3jA:
undetectable
3m0wI-4s3jA:
undetectable
3m0wJ-4s3jA:
undetectable		 3m0wA-4s3jA:
13.75
3m0wB-4s3jA:
13.75
3m0wI-4s3jA:
13.75
3m0wJ-4s3jA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		5 / 12 VAL A   5
ASN A  31
ILE A  65
TYR A  69
ILE A   2
 None
None
None
EDO  A 501 (-2.7A)
None
 1.48A 3q5pA-4s3jA:
undetectable		 3q5pA-4s3jA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		4 / 5 SER A 103
THR A 425
GLU A 105
ASP A 213
 None
 1.33A 3tm4A-4s3jA:
undetectable		 3tm4A-4s3jA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		4 / 5 SER A 103
THR A 425
GLU A 105
ASP A 213
 None
 1.31A 3tm4B-4s3jA:
undetectable		 3tm4B-4s3jA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		4 / 6 SER A 405
TYR A 109
VAL A 171
THR A 125
 None
 1.08A 3tneA-4s3jA:
undetectable		 3tneA-4s3jA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		4 / 5 THR A 166
GLY A 164
PRO A 130
ASN A 129
 None
 1.18A 3u8qA-4s3jA:
undetectable		 3u8qA-4s3jA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 GLN A 365
PHE A 362
TYR A 360
 None
 0.85A 3ucjB-4s3jA:
undetectable		 3ucjB-4s3jA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 GLN A 365
PHE A 362
TYR A 360
 None
 0.93A 3ucjA-4s3jA:
undetectable		 3ucjA-4s3jA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 173
VAL A 171
GLU A 219
 None
 0.69A 3v4tA-4s3jA:
undetectable
3v4tD-4s3jA:
undetectable		 3v4tA-4s3jA:
22.27
3v4tD-4s3jA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		7 / 11 PHE A 138
ASP A 217
GLU A 219
MET A 281
TYR A 283
TYR A 324
TRP A 407
 None
 0.97A 3wqvA-4s3jA:
32.2		 3wqvA-4s3jA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		7 / 11 PHE A 138
ASP A 217
MET A 281
TYR A 283
ASP A 284
TYR A 324
TRP A 407
 None
 0.89A 3wqvA-4s3jA:
32.2		 3wqvA-4s3jA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		7 / 11 PHE A 138
ASP A 217
GLU A 219
MET A 281
TYR A 283
TYR A 324
TRP A 407
 None
 0.99A 3wqwA-4s3jA:
32.1		 3wqwA-4s3jA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		7 / 11 PHE A 138
ASP A 217
MET A 281
TYR A 283
ASP A 284
TYR A 324
TRP A 407
 None
 0.91A 3wqwA-4s3jA:
32.1		 3wqwA-4s3jA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		5 / 12 ILE A 298
ILE A 295
TYR A 324
MET A 319
LEU A 305
 None
 1.19A 4a84A-4s3jA:
undetectable		 4a84A-4s3jA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		3 / 3 THR A 166
PRO A 168
THR A 162
 None
 0.77A 4hivD-4s3jA:
undetectable		 4hivD-4s3jA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HZ2_A_BEZA302_0
(GLUTATHIONE
S-TRANSFERASE DOMAIN)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		4 / 6 MET A 318
SER A 405
TYR A 134
TYR A 109
 None
 1.35A 4hz2A-4s3jA:
0.0		 4hz2A-4s3jA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		4 / 7 LEU A 411
PRO A 367
SER A 388
VAL A 381
 None
 0.95A 4klrA-4s3jA:
undetectable		 4klrA-4s3jA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		4 / 7 GLN A 365
ARG A  64
ALA A 386
ILE A   4
 None
 0.95A 4txnA-4s3jA:
undetectable		 4txnA-4s3jA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		4 / 7 GLN A 365
ARG A  64
ALA A 386
ILE A   4
 None
 0.95A 4txnB-4s3jA:
undetectable		 4txnB-4s3jA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		4 / 7 GLN A 365
ARG A  64
ALA A 386
ILE A   4
 None
 0.94A 4txnC-4s3jA:
undetectable		 4txnC-4s3jA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		4 / 7 GLN A 365
ARG A  64
ALA A 386
ILE A   4
 None
 0.94A 4txnD-4s3jA:
undetectable		 4txnD-4s3jA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		5 / 8 PHE A 138
GLU A 219
TYR A 283
ASP A 284
TRP A 407
 None
 1.09A 5gqbA-4s3jA:
28.6		 5gqbA-4s3jA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		5 / 11 ILE A 117
VAL A 122
THR A 125
ASN A 129
ILE A 160
 None
 1.14A 5lg3A-4s3jA:
undetectable		 5lg3A-4s3jA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		5 / 12 ILE A 117
VAL A 122
THR A 125
ASN A 129
ILE A 160
 None
 1.10A 5lg3E-4s3jA:
undetectable		 5lg3E-4s3jA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		5 / 10 ILE A 117
VAL A 122
THR A 125
ASN A 129
ILE A 160
 None
 1.12A 5lg3F-4s3jA:
undetectable		 5lg3F-4s3jA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		5 / 10 ILE A 117
VAL A 122
THR A 125
ASN A 129
ILE A 160
 None
 1.10A 5lg3G-4s3jA:
undetectable		 5lg3G-4s3jA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		5 / 10 ILE A 117
VAL A 122
THR A 125
ASN A 129
ILE A 160
 None
 1.10A 5lg3H-4s3jA:
undetectable		 5lg3H-4s3jA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		5 / 12 ILE A 117
VAL A 122
THR A 125
ASN A 129
ILE A 160
 None
 1.18A 5lg3J-4s3jA:
undetectable		 5lg3J-4s3jA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		4 / 7 THR A 248
LYS A 197
GLN A 204
GLU A 207
 None
 1.06A 5tudA-4s3jA:
undetectable		 5tudA-4s3jA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4s3j CORTICAL-LYTIC
ENZYME
(Bacillus
cereus) 		5 / 12 ILE A 188
HIS A 266
PHE A 198
THR A 249
THR A 248
 None
 1.17A 6bbsA-4s3jA:
undetectable		 6bbsA-4s3jA:
11.06