SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4s3p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		11 / 12 SER A 199
TYR A 201
GLN A 411
TRP A 413
HIS A 449
GLU A 496
HIS A 547
ASP A 548
ASN A 648
PRO A 650
TRP A 659
 None
 0.41A 1eswA-4s3pA:
34.6		 1eswA-4s3pA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 11 LEU A 153
ASN A 158
TYR A 151
GLY A 160
LEU A 663
 None
 1.35A 1fkpA-4s3pA:
undetectable		 1fkpA-4s3pA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		4 / 6 PHE A 222
ILE A 214
LYS A 259
ALA A 262
 None
 1.25A 1hk2A-4s3pA:
undetectable		 1hk2A-4s3pA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		4 / 6 VAL A 493
LEU A 445
MET A 453
SER A 452
 None
 1.07A 1wrlB-4s3pA:
undetectable		 1wrlB-4s3pA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 12 LEU A 680
ASN A 677
ALA A 672
LEU A 667
LEU A 641
 None
 1.46A 1ya3B-4s3pA:
undetectable		 1ya3B-4s3pA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		4 / 8 LEU A 621
GLY A 620
LEU A 590
PRO A 533
 None
 0.85A 1ya4A-4s3pA:
undetectable		 1ya4A-4s3pA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		4 / 7 LEU A 621
GLY A 620
LEU A 590
PRO A 533
 None
 0.84A 1ya4B-4s3pA:
2.6		 1ya4B-4s3pA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 9 LEU A 375
HIS A 188
ARG A 373
LEU A 445
ALA A 437
 None
 1.11A 2bxeA-4s3pA:
undetectable		 2bxeA-4s3pA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 10 LEU A 375
HIS A 188
ARG A 373
LEU A 445
ALA A 437
 None
 1.14A 2bxeB-4s3pA:
undetectable		 2bxeB-4s3pA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 12 LEU A 680
ASN A 677
ALA A 672
LEU A 667
LEU A 641
 None
 1.48A 2oaxC-4s3pA:
undetectable		 2oaxC-4s3pA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_D_MTXD617_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 12 PHE A 181
SER A 180
ILE A 494
LEU A 632
CYH A 147
 None
 1.14A 2oipD-4s3pA:
undetectable		 2oipD-4s3pA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 11 SER A 199
TYR A 201
ASP A 448
HIS A 547
TRP A 659
 None
 1.00A 2owcA-4s3pA:
34.2		 2owcA-4s3pA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		8 / 11 SER A 199
TYR A 201
TRP A 413
HIS A 547
ASP A 548
ASN A 648
PRO A 650
TRP A 659
 None
 0.58A 2owcA-4s3pA:
34.2		 2owcA-4s3pA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		6 / 11 TYR A 201
GLN A 411
TRP A 413
HIS A 547
ASP A 548
TRP A 659
 None
 0.67A 2owcA-4s3pA:
34.2		 2owcA-4s3pA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 11 SER A 199
TYR A 201
ASP A 448
HIS A 547
TRP A 659
 None
 1.00A 2owwA-4s3pA:
34.1		 2owwA-4s3pA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		7 / 11 SER A 199
TYR A 201
HIS A 547
ASP A 548
ASN A 648
PRO A 650
TRP A 659
 None
 0.32A 2owwA-4s3pA:
34.1		 2owwA-4s3pA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		6 / 11 SER A 199
TYR A 201
TRP A 413
HIS A 547
ASP A 548
TRP A 659
 None
 0.67A 2owwA-4s3pA:
34.1		 2owwA-4s3pA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI8_B_HNQB255_1
(CATHEPSIN B)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		4 / 6 GLN A 411
GLY A 410
HIS A 449
TRP A 413
 None
 1.46A 3ai8B-4s3pA:
undetectable		 3ai8B-4s3pA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		4 / 8 GLY A  94
VAL A  70
LEU A 113
PRO A  53
 None
 1.12A 3bgdB-4s3pA:
undetectable		 3bgdB-4s3pA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_A_BCZA1001_0
(NEURAMINIDASE)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 12 ARG A 436
GLU A 485
LEU A 435
GLU A 106
TYR A 108
 None
 1.27A 3k39A-4s3pA:
undetectable		 3k39A-4s3pA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_E_BCZE1001_0
(NEURAMINIDASE)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 12 ARG A 436
GLU A 485
LEU A 435
GLU A 106
TYR A 108
 None
 1.26A 3k39E-4s3pA:
undetectable		 3k39E-4s3pA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_F_BCZF1001_0
(NEURAMINIDASE)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 12 ARG A 436
GLU A 485
LEU A 435
GLU A 106
TYR A 108
 None
 1.27A 3k39F-4s3pA:
undetectable		 3k39F-4s3pA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_G_BCZG1001_0
(NEURAMINIDASE)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 12 ARG A 436
GLU A 485
LEU A 435
GLU A 106
TYR A 108
 None
 1.26A 3k39G-4s3pA:
undetectable		 3k39G-4s3pA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_H_BCZH1001_0
(NEURAMINIDASE)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 12 ARG A 436
GLU A 485
LEU A 435
GLU A 106
TYR A 108
 None
 1.28A 3k39H-4s3pA:
undetectable		 3k39H-4s3pA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_O_BCZO1001_0
(NEURAMINIDASE)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 12 ARG A 436
GLU A 485
LEU A 435
GLU A 106
TYR A 108
 None
 1.29A 3k39O-4s3pA:
undetectable		 3k39O-4s3pA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		3 / 3 ALA A 532
ARG A 531
LYS A 518
 None
 0.97A 3kp3B-4s3pA:
undetectable		 3kp3B-4s3pA:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		4 / 5 ARG A 688
LEU A 635
ILE A 369
PHE A 181
 None
 1.24A 3ln1D-4s3pA:
0.2		 3ln1D-4s3pA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP1_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 10 LEU A 153
ASN A 158
TYR A 151
GLY A 160
LEU A 663
 None
 1.36A 3lp1A-4s3pA:
undetectable		 3lp1A-4s3pA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC800_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		3 / 3 ASP A 627
ARG A 623
ALA A 626
 None
 0.70A 3mbgC-4s3pA:
undetectable		 3mbgC-4s3pA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 12 LEU A 621
TYR A 555
TRP A 556
LEU A 617
PRO A 615
 None
 1.11A 3mecA-4s3pA:
undetectable		 3mecA-4s3pA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 12 LEU A 680
ASN A 677
ALA A 672
LEU A 667
LEU A 641
 None
 1.50A 3vhuA-4s3pA:
undetectable		 3vhuA-4s3pA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 11 LEU A 667
PRO A 637
VAL A 148
VAL A 676
TRP A 640
 None
 1.48A 4mk4B-4s3pA:
0.9		 4mk4B-4s3pA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 10 LEU A 635
LEU A 683
LEU A 594
ASN A 618
LEU A 617
 None
 1.07A 4po0A-4s3pA:
undetectable		 4po0A-4s3pA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		6 / 12 ARG A 446
ASP A 448
GLU A 496
GLY A 499
PHE A 522
HIS A 547
 None
 0.95A 5csyB-4s3pA:
32.4		 5csyB-4s3pA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 12 ARG A 446
ASP A 448
PHE A 522
HIS A 547
ASP A 548
 None
 0.89A 5csyB-4s3pA:
32.4		 5csyB-4s3pA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 12 GLN A 411
TRP A 413
GLU A 496
GLY A 499
PHE A 522
 None
 0.75A 5csyB-4s3pA:
32.4		 5csyB-4s3pA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		6 / 12 TRP A 413
ARG A 446
GLU A 496
GLY A 499
PHE A 522
HIS A 547
 None
 0.79A 5csyB-4s3pA:
32.4		 5csyB-4s3pA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 12 TRP A 413
ARG A 446
PHE A 522
HIS A 547
ASP A 548
 None
 0.87A 5csyB-4s3pA:
32.4		 5csyB-4s3pA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_C_PPFC601_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		4 / 6 ARG A 245
ASP A 163
GLY A 162
ASP A 166
 None
 1.26A 5hp1C-4s3pA:
undetectable		 5hp1C-4s3pA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		4 / 9 ILE A 481
PHE A 431
VAL A  57
ASP A 476
 None
 0.97A 5lg3I-4s3pA:
undetectable		 5lg3I-4s3pA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		4 / 8 GLY A 651
GLN A 149
TYR A 151
ASP A 548
 None
 1.06A 5vlmB-4s3pA:
undetectable		 5vlmB-4s3pA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		4 / 7 GLY A 651
GLN A 149
TYR A 151
ASP A 548
 None
 1.00A 5vlmG-4s3pA:
undetectable		 5vlmG-4s3pA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		4 / 8 GLY A  14
ILE A  15
ASP A 419
PRO A 417
 None
 0.88A 6ag0A-4s3pA:
3.0		 6ag0A-4s3pA:
8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_C_HISC402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		5 / 9 VAL A 148
LEU A 680
GLY A 634
LEU A 635
GLN A 636
 None
 1.22A 6czmB-4s3pA:
undetectable
6czmC-4s3pA:
undetectable		 6czmB-4s3pA:
19.00
6czmC-4s3pA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		3 / 3 TYR A 191
HIS A 302
PHE A 298
 None
 0.95A 6esmA-4s3pA:
undetectable		 6esmA-4s3pA:
8.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 4s3p 4-ALPHA-GLUCANOTRANS
FERASE
(Escherichia
coli) 		4 / 6 GLU A 227
TRP A 231
ALA A 230
GLN A 229
 None
 1.41A 6f6jC-4s3pA:
undetectable
6f6jD-4s3pA:
undetectable		 6f6jC-4s3pA:
19.31
6f6jD-4s3pA:
19.31