SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4tjv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 4tjv VACUOLAR-SORTING
RECEPTOR 1
(Arabidopsis
thaliana) 		4 / 8 LEU A 150
ALA A  43
PHE A  21
VAL A  23
 None
 0.87A 1epbB-4tjvA:
undetectable		 1epbB-4tjvA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ4_X_DXCX75_0
(CYTOCHROME C7)		 4tjv VACUOLAR-SORTING
RECEPTOR 1
(Arabidopsis
thaliana) 		5 / 9 ILE A 151
LEU A  28
ILE A 115
PHE A  90
GLY A  58
 None
 1.35A 3sj4X-4tjvA:
undetectable		 3sj4X-4tjvA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 4tjv VACUOLAR-SORTING
RECEPTOR 1
(Arabidopsis
thaliana) 		4 / 7 ASP A 129
THR A 130
ARG A  95
PHE A  21
 None
 1.49A 4o4dA-4tjvA:
undetectable		 4o4dA-4tjvA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 4tjv VACUOLAR-SORTING
RECEPTOR 1
(Arabidopsis
thaliana) 		5 / 12 ILE A 115
ALA A 112
THR A  31
VAL A  30
LEU A 116
 None
 1.40A 4qzuA-4tjvA:
undetectable		 4qzuA-4tjvA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 4tjv VACUOLAR-SORTING
RECEPTOR 1
(Arabidopsis
thaliana) 		5 / 12 ILE A 159
ILE A 151
ALA A 149
ILE A 146
ALA A 113
 None
 0.99A 5vceA-4tjvA:
undetectable		 5vceA-4tjvA:
17.43