SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4tkc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7P_A_ACRA1481_1 (GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE)	4tkc	MANNOSE RECOGNIZING LECTIN (Marasmius oreades)	4 / 6	HIS A 4 ARG A 32 GLU A 30 TYR A 2	None	1.07A	5x7pA-4tkcA: undetectable	5x7pA-4tkcA: 7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7P_B_ACRB1481_1 (GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE)	4tkc	MANNOSE RECOGNIZING LECTIN (Marasmius oreades)	4 / 6	HIS A 4 ARG A 32 GLU A 30 TYR A 2	None	1.08A	5x7pB-4tkcA: undetectable	5x7pB-4tkcA: 7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7Q_A_ACRA1481_1 (GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE)	4tkc	MANNOSE RECOGNIZING LECTIN (Marasmius oreades)	4 / 6	HIS A 4 ARG A 32 GLU A 30 TYR A 2	None	1.04A	5x7qA-4tkcA: undetectable	5x7qA-4tkcA: 7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7Q_B_ACRB1481_1 (GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE)	4tkc	MANNOSE RECOGNIZING LECTIN (Marasmius oreades)	4 / 6	HIS A 4 ARG A 32 GLU A 30 TYR A 2	None	1.10A	5x7qB-4tkcA: undetectable	5x7qB-4tkcA: 7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7R_A_ACRA1481_1 (GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE)	4tkc	MANNOSE RECOGNIZING LECTIN (Marasmius oreades)	4 / 6	HIS A 4 ARG A 32 GLU A 30 TYR A 2	None	1.04A	5x7rA-4tkcA: undetectable	5x7rA-4tkcA: 7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7R_B_ACRB1481_1 (GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE)	4tkc	MANNOSE RECOGNIZING LECTIN (Marasmius oreades)	4 / 6	HIS A 4 ARG A 32 GLU A 30 TYR A 2	None	1.09A	5x7rB-4tkcA: undetectable	5x7rB-4tkcA: 7.10

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5X7P_A_ACRA1481_1","GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE","4tkc","MANNOSE RECOGNIZING LECTIN","Marasmius oreades",4,"HIS A   4;ARG A  32;GLU A  30;TYR A   2","None","1.07A","5x7pA-4tkcA:undetectable","5x7pA-4tkcA:7.10"],["5X7P_B_ACRB1481_1","GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE","4tkc","MANNOSE RECOGNIZING LECTIN","Marasmius oreades",4,"HIS A   4;ARG A  32;GLU A  30;TYR A   2","None","1.08A","5x7pB-4tkcA:undetectable","5x7pB-4tkcA:7.10"],["5X7Q_A_ACRA1481_1","GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE","4tkc","MANNOSE RECOGNIZING LECTIN","Marasmius oreades",4,"HIS A   4;ARG A  32;GLU A  30;TYR A   2","None","1.04A","5x7qA-4tkcA:undetectable","5x7qA-4tkcA:7.10"],["5X7Q_B_ACRB1481_1","GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE","4tkc","MANNOSE RECOGNIZING LECTIN","Marasmius oreades",4,"HIS A   4;ARG A  32;GLU A  30;TYR A   2","None","1.10A","5x7qB-4tkcA:undetectable","5x7qB-4tkcA:7.10"],["5X7R_A_ACRA1481_1","GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE","4tkc","MANNOSE RECOGNIZING LECTIN","Marasmius oreades",4,"HIS A   4;ARG A  32;GLU A  30;TYR A   2","None","1.04A","5x7rA-4tkcA:undetectable","5x7rA-4tkcA:7.10"],["5X7R_B_ACRB1481_1","GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE","4tkc","MANNOSE RECOGNIZING LECTIN","Marasmius oreades",4,"HIS A   4;ARG A  32;GLU A  30;TYR A   2","None","1.09A","5x7rB-4tkcA:undetectable","5x7rB-4tkcA:7.10"]]