SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4tl3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_1
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 4tl3 ANABAENA SENSORY
RHODOPSIN
(Nostoc
sp.
PCC
7120) 		4 / 7 GLN A 157
THR A 154
SER A 158
TYR A 165
 None
 1.20A 1eiiA-4tl3A:
undetectable		 1eiiA-4tl3A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4tl3 ANABAENA SENSORY
RHODOPSIN
(Nostoc
sp.
PCC
7120) 		4 / 6 LEU A  84
TYR A 165
ARG A 151
THR A 170
 None
None
None
PEE  A 304 ( 4.3A)
 0.80A 2zxwA-4tl3A:
2.8
2zxwJ-4tl3A:
undetectable		 2zxwA-4tl3A:
20.80
2zxwJ-4tl3A:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4tl3 ANABAENA SENSORY
RHODOPSIN
(Nostoc
sp.
PCC
7120) 		4 / 6 LEU A  84
TYR A 165
ARG A 151
THR A 170
 None
None
None
PEE  A 304 ( 4.3A)
 0.89A 3abmA-4tl3A:
2.7
3abmJ-4tl3A:
undetectable		 3abmA-4tl3A:
20.80
3abmJ-4tl3A:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA451_1
(CYTOCHROME P450
164A2)		 4tl3 ANABAENA SENSORY
RHODOPSIN
(Nostoc
sp.
PCC
7120) 		5 / 10 ALA A  91
LEU A  87
LEU A 105
ILE A 146
THR A 108
 None
None
None
None
PEE  A 319 ( 4.4A)
 1.32A 3r9cA-4tl3A:
undetectable		 3r9cA-4tl3A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 4tl3 ANABAENA SENSORY
RHODOPSIN
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A  87
PHE A 213
GLN A  93
GLY A 220
LEU A 221
 None
 1.26A 4j7xB-4tl3A:
undetectable		 4j7xB-4tl3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 4tl3 ANABAENA SENSORY
RHODOPSIN
(Nostoc
sp.
PCC
7120) 		5 / 12 THR A  90
SER A  86
GLY A 220
GLY A  31
PRO A  33
 None
 1.45A 4uinH-4tl3A:
undetectable
4uinL-4tl3A:
undetectable		 4uinH-4tl3A:
20.24
4uinL-4tl3A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 4tl3 ANABAENA SENSORY
RHODOPSIN
(Nostoc
sp.
PCC
7120) 		4 / 8 PHE A 213
SER A 209
TRP A 176
TYR A 179
 None
RET  A 301 ( 4.1A)
RET  A 301 (-3.8A)
RET  A 301 (-3.3A)
 1.29A 5amiB-4tl3A:
undetectable		 5amiB-4tl3A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4tl3 ANABAENA SENSORY
RHODOPSIN
(Nostoc
sp.
PCC
7120) 		4 / 6 LEU A  84
TYR A 165
ARG A 151
THR A 170
 None
None
None
PEE  A 304 ( 4.3A)
 0.88A 5x1fA-4tl3A:
2.3
5x1fJ-4tl3A:
undetectable		 5x1fA-4tl3A:
20.80
5x1fJ-4tl3A:
12.67