SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4tlp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_B_SALB1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4tlp CHYMOTRYPSIN
INHIBITOR 3
(Psophocarpus
tetragonolobus) 		5 / 9 PHE A  82
THR A  36
VAL A  49
LEU A 163
ALA A  94
 None
 1.49A 3ax7B-4tlpA:
undetectable		 3ax7B-4tlpA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4tlp CHYMOTRYPSIN
INHIBITOR 3
(Psophocarpus
tetragonolobus) 		5 / 12 GLY A  18
ILE A 153
GLY A  32
PHE A 122
THR A  20
 None
 1.27A 5eslA-4tlpA:
undetectable		 5eslA-4tlpA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_0
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4tlp CHYMOTRYPSIN
INHIBITOR 3
(Psophocarpus
tetragonolobus) 		5 / 12 GLY A  19
ILE A 153
GLY A  32
PHE A 122
THR A  20
 None
 1.16A 6e8qA-4tlpA:
undetectable		 6e8qA-4tlpA:
18.24