SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4tpg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY
(Shewanella
oneidensis) 		5 / 11 MET A  31
ARG A  25
GLY A 116
GLU A  24
ILE A  88
 None
 1.31A 1odiA-4tpgA:
undetectable		 1odiA-4tpgA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY
(Shewanella
oneidensis) 		5 / 11 MET A  31
ARG A  25
GLY A 116
GLU A  24
ILE A  88
 None
 1.35A 1odiC-4tpgA:
undetectable		 1odiC-4tpgA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY
(Shewanella
oneidensis) 		5 / 11 MET A  31
ARG A  25
GLY A 116
GLU A  24
ILE A  88
 None
 1.33A 1odiD-4tpgA:
undetectable		 1odiD-4tpgA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY
(Shewanella
oneidensis) 		5 / 11 MET A  31
ARG A  25
GLY A 116
GLU A  24
ILE A  88
 None
 1.30A 1odiE-4tpgA:
undetectable		 1odiE-4tpgA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY
(Shewanella
oneidensis) 		5 / 11 MET A  31
ARG A  25
GLY A 116
GLU A  24
ILE A  88
 None
 1.30A 1odiF-4tpgA:
undetectable		 1odiF-4tpgA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY
(Shewanella
oneidensis) 		4 / 6 ALA A 109
LEU A 110
ILE A 113
CYH A 186
 None
 0.94A 1sbrA-4tpgA:
undetectable
1sbrB-4tpgA:
undetectable		 1sbrA-4tpgA:
16.57
1sbrB-4tpgA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY
(Shewanella
oneidensis) 		5 / 12 ILE A 392
PHE A 325
LEU A 328
ALA A 327
VAL A 306
 None
 1.09A 4k6iA-4tpgA:
undetectable		 4k6iA-4tpgA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY
(Shewanella
oneidensis) 		5 / 12 VAL A 405
PHE A 288
VAL A 367
GLY A 401
THR A 284
 None
 1.07A 4mm6A-4tpgA:
1.3		 4mm6A-4tpgA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY
(Shewanella
oneidensis) 		5 / 12 LEU A 160
LEU A  34
ALA A 181
ASN A 169
ALA A 323
 None
 0.89A 4o2bD-4tpgA:
undetectable		 4o2bD-4tpgA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY
(Shewanella
oneidensis) 		5 / 12 ILE A 333
TYR A 291
THR A 296
ALA A 299
TYR A  29
 None
 1.48A 4u14A-4tpgA:
2.8		 4u14A-4tpgA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY
(Shewanella
oneidensis) 		5 / 12 LEU A 160
LEU A  34
ALA A 181
ASN A 169
ALA A 323
 None
 1.13A 4x1kA-4tpgA:
undetectable
4x1kB-4tpgA:
undetectable		 4x1kA-4tpgA:
22.58
4x1kB-4tpgA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_A_ACTA404_0
(PROTON-GATED ION
CHANNEL)		 4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY
(Shewanella
oneidensis) 		4 / 4 LEU A  89
ILE A 113
ARG A  25
TYR A  93
 None
 1.02A 4zzbA-4tpgA:
2.1		 4zzbA-4tpgA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA406_0
(PROTON-GATED ION
CHANNEL)		 4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY
(Shewanella
oneidensis) 		4 / 4 LEU A  89
ILE A 113
ARG A  25
TYR A  93
 None
 1.08A 4zzcA-4tpgA:
2.8		 4zzcA-4tpgA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY
(Shewanella
oneidensis) 		5 / 12 LEU A 160
LEU A  34
ALA A 181
ASN A 169
ALA A 323
 None
 0.92A 5eypB-4tpgA:
undetectable		 5eypB-4tpgA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_2
(TUBULIN BETA-2B
CHAIN)		 4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY
(Shewanella
oneidensis) 		5 / 12 LEU A 160
LEU A  34
ALA A 181
ASN A 169
ALA A 323
 None
 0.92A 5nm5B-4tpgA:
undetectable		 5nm5B-4tpgA:
20.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GS4_A_F9EA601_0
(DIPEPTIDE AND
TRIPEPTIDE PERMEASE
A)		 4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY
(Shewanella
oneidensis) 		6 / 10 TYR A  29
LYS A 121
MET A 158
PHE A 288
ASN A 329
GLU A 402
 None
 1.22A 6gs4A-4tpgA:
49.5		 6gs4A-4tpgA:
39.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GS4_A_F9EA601_0
(DIPEPTIDE AND
TRIPEPTIDE PERMEASE
A)		 4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY
(Shewanella
oneidensis) 		9 / 10 TYR A  29
TYR A 147
ASN A 151
SER A 154
MET A 158
PHE A 288
ASN A 329
PRO A 330
GLU A 402
 None
 0.67A 6gs4A-4tpgA:
49.5		 6gs4A-4tpgA:
39.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GZ9_A_TXCA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY
(Shewanella
oneidensis) 		5 / 10 TYR A  29
VAL A 150
ASN A 151
ASN A 329
PRO A 330
 None
 0.57A 6gz9A-4tpgA:
38.8		 6gz9A-4tpgA:
10.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY
(Shewanella
oneidensis) 		6 / 6 VAL A 150
ASN A 151
ASN A 329
PRO A 330
ILE A 333
GLU A 402
 None
 0.66A 6h7uA-4tpgA:
36.4		 6h7uA-4tpgA:
30.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY
(Shewanella
oneidensis) 		7 / 8 TYR A  29
VAL A 150
ASN A 151
ASN A 329
PRO A 330
ILE A 333
GLU A 402
 None
 0.61A 6hzpA-4tpgA:
38.9		 6hzpA-4tpgA:
30.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY
(Shewanella
oneidensis) 		3 / 3 ASN A 305
PRO A 456
GLN A 458
 None
 0.96A 6jogA-4tpgA:
undetectable		 6jogA-4tpgA:
16.41