SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4tpu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5T_A_IPHA902_0 (PROTEIN ARGONAUTE-2)	4tpu	RUBREDOXIN (Methanosarcina acetivorans)	4 / 6	ARG A 112 ILE A 115 ILE A 65 ASP A 62	NA A 306 ( 4.4A) None None None	1.21A	4w5tA-4tpuA: undetectable	4w5tA-4tpuA: 12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4C_A_IPHA903_0 (PROTEIN ARGONAUTE-2)	4tpu	RUBREDOXIN (Methanosarcina acetivorans)	4 / 6	ARG A 112 ILE A 115 ILE A 65 ASP A 62	NA A 306 ( 4.4A) None None None	1.19A	4z4cA-4tpuA: undetectable	4z4cA-4tpuA: 12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4D_A_IPHA902_0 (PROTEIN ARGONAUTE-2)	4tpu	RUBREDOXIN (Methanosarcina acetivorans)	4 / 6	ARG A 112 ILE A 115 ILE A 65 ASP A 62	NA A 306 ( 4.4A) None None None	1.20A	4z4dA-4tpuA: undetectable	4z4dA-4tpuA: 12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B89_A_NOVA403_2 (LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB)	4tpu	RUBREDOXIN (Methanosarcina acetivorans)	4 / 6	ARG A 11 ARG A 12 LEU A 13 GLN A 15	None	1.08A	6b89B-4tpuA: undetectable	6b89B-4tpuA: 17.22

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4W5T_A_IPHA902_0","PROTEIN ARGONAUTE-2","4tpu","RUBREDOXIN","Methanosarcina acetivorans",4,"ARG A 112;ILE A 115;ILE A  65;ASP A  62"," NA A 306 ( 4.4A);None;None;None","1.21A","4w5tA-4tpuA:undetectable","4w5tA-4tpuA:12.02"],["4Z4C_A_IPHA903_0","PROTEIN ARGONAUTE-2","4tpu","RUBREDOXIN","Methanosarcina acetivorans",4,"ARG A 112;ILE A 115;ILE A  65;ASP A  62"," NA A 306 ( 4.4A);None;None;None","1.19A","4z4cA-4tpuA:undetectable","4z4cA-4tpuA:12.02"],["4Z4D_A_IPHA902_0","PROTEIN ARGONAUTE-2","4tpu","RUBREDOXIN","Methanosarcina acetivorans",4,"ARG A 112;ILE A 115;ILE A  65;ASP A  62"," NA A 306 ( 4.4A);None;None;None","1.20A","4z4dA-4tpuA:undetectable","4z4dA-4tpuA:12.02"],["6B89_A_NOVA403_2","LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB;LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB","4tpu","RUBREDOXIN","Methanosarcina acetivorans",4,"ARG A  11;ARG A  12;LEU A  13;GLN A  15","None","1.08A","6b89B-4tpuA:undetectable","6b89B-4tpuA:17.22"]]