SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4tq2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_A_T3A1_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 4tq2 PUTATIVE
PHYCOERYTHRIN LYASE
(Guillardia
theta) 		5 / 12 ILE A 151
ILE A 152
ALA A  24
LEU A 161
HIS A 156
 None
 0.92A 1bsxA-4tq2A:
undetectable		 1bsxA-4tq2A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_B_T3B2_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 4tq2 PUTATIVE
PHYCOERYTHRIN LYASE
(Guillardia
theta) 		5 / 12 ILE A 151
ILE A 152
ALA A  24
LEU A 161
HIS A 156
 None
 0.92A 1bsxB-4tq2A:
undetectable		 1bsxB-4tq2A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_A_DVAA35_0
(UBIQUITIN)		 4tq2 PUTATIVE
PHYCOERYTHRIN LYASE
(Guillardia
theta) 		4 / 4 GLN A  -8
GLU A  -3
ILE A  -4
PRO A  -9
 None
 1.33A 2fcnA-4tq2A:
undetectable		 2fcnA-4tq2A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H79_A_T3A1_1
(THRA PROTEIN)		 4tq2 PUTATIVE
PHYCOERYTHRIN LYASE
(Guillardia
theta) 		5 / 12 ILE A 151
ILE A 152
ALA A  24
LEU A 161
HIS A 156
 None
 0.92A 2h79A-4tq2A:
undetectable		 2h79A-4tq2A:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4tq2 PUTATIVE
PHYCOERYTHRIN LYASE
(Guillardia
theta) 		4 / 5 LEU A 165
THR A 167
HIS A  21
LEU A  28
 None
 1.24A 3ce6D-4tq2A:
undetectable		 3ce6D-4tq2A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 4tq2 PUTATIVE
PHYCOERYTHRIN LYASE
(Guillardia
theta) 		5 / 12 ILE A 151
ILE A 152
ALA A  24
LEU A 161
HIS A 156
 None
 0.92A 3gwsX-4tq2A:
undetectable		 3gwsX-4tq2A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 4tq2 PUTATIVE
PHYCOERYTHRIN LYASE
(Guillardia
theta) 		5 / 12 ILE A 151
ILE A 152
ALA A  24
LEU A 161
HIS A 156
 None
 0.83A 3uvvA-4tq2A:
undetectable		 3uvvA-4tq2A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4tq2 PUTATIVE
PHYCOERYTHRIN LYASE
(Guillardia
theta) 		3 / 3 THR A  53
THR A  85
LEU A  99
 None
 0.54A 5m66D-4tq2A:
undetectable		 5m66D-4tq2A:
17.23