SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4tqt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		4 / 5 HIS A  61
HIS A 184
HIS A 240
ASP A 317
 ZN  A 501 (-3.4A)
ZN  A 502 (-3.3A)
ZN  A 502 (-3.5A)
ZN  A 501 (-2.8A)
 0.41A 1e9yB-4tqtA:
21.7		 1e9yB-4tqtA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 6 HIS A  61
HIS A  63
HIS A 184
HIS A 240
ASP A 317
 ZN  A 501 (-3.4A)
ZN  A 501 (-3.3A)
ZN  A 502 (-3.3A)
ZN  A 502 (-3.5A)
ZN  A 501 (-2.8A)
 0.50A 1fweC-4tqtA:
22.5		 1fweC-4tqtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_2
(POL POLYPROTEIN)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 12 GLY A 389
ALA A 390
ASP A 391
ASP A 393
THR A  17
 None
 0.97A 1k6cB-4tqtA:
undetectable		 1k6cB-4tqtA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 12 ILE A 226
GLY A 262
VAL A 260
ALA A 315
HIS A 240
 None
None
None
None
ZN  A 502 (-3.5A)
 1.38A 1nbhA-4tqtA:
undetectable		 1nbhA-4tqtA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 12 ILE A 226
GLY A 262
VAL A 260
ALA A 315
HIS A 240
 None
None
None
None
ZN  A 502 (-3.5A)
 1.37A 1nbhD-4tqtA:
undetectable		 1nbhD-4tqtA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 12 GLU A 263
HIS A 240
HIS A 209
HIS A 184
TYR A 156
 None
ZN  A 502 (-3.5A)
None
ZN  A 502 (-3.3A)
None
 1.41A 1o86A-4tqtA:
undetectable		 1o86A-4tqtA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_1
(POL POLYPROTEIN)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		6 / 11 GLY A 389
ALA A 390
ASP A 391
ASP A 393
THR A  17
VAL A 386
 None
 1.32A 1t7jA-4tqtA:
undetectable		 1t7jA-4tqtA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 9 VAL A  15
THR A  17
VAL A 387
ILE A  33
VAL A 386
 None
 1.40A 2l8mA-4tqtA:
undetectable		 2l8mA-4tqtA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 11 ASP A 317
HIS A  61
GLU A 186
HIS A 240
HIS A 209
 ZN  A 501 (-2.8A)
ZN  A 501 (-3.4A)
None
ZN  A 502 (-3.5A)
None
 1.23A 2q0jB-4tqtA:
undetectable		 2q0jB-4tqtA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		3 / 3 ARG A 456
THR A  62
VAL A  93
 None
 0.88A 2q64A-4tqtA:
undetectable		 2q64A-4tqtA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_FFOB505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 12 GLY A  13
VAL A 387
ALA A  48
PRO A  55
GLY A  56
 None
 1.08A 2vmyA-4tqtA:
undetectable		 2vmyA-4tqtA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 11 VAL A 239
LEU A 182
ILE A 373
PRO A  60
THR A  62
 None
KCX  A 151 ( 4.4A)
None
None
None
 1.37A 3bjwE-4tqtA:
undetectable		 3bjwE-4tqtA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_1
(PROTEASE)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 12 GLY A 389
ALA A 390
ASP A 391
ASP A 393
THR A  17
 None
 0.94A 3el4A-4tqtA:
undetectable		 3el4A-4tqtA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		4 / 5 PRO A 362
VAL A 355
THR A  90
GLY A  88
 None
 1.03A 3elzB-4tqtA:
undetectable		 3elzB-4tqtA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		3 / 3 GLU A 218
VAL A 241
CYH A 243
 None
 0.91A 3fbxA-4tqtA:
undetectable		 3fbxA-4tqtA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		3 / 3 MET A 227
MET A 180
PHE A 168
 None
EDO  A 505 ( 4.9A)
None
 1.26A 3gn8A-4tqtA:
undetectable		 3gn8A-4tqtA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		3 / 3 SER A 310
GLY A 309
GLN A 312
 None
 0.61A 3v4tH-4tqtA:
undetectable		 3v4tH-4tqtA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		4 / 6 THR A 334
ASN A 332
GLY A 331
ASP A 204
 None
 1.29A 3w9tE-4tqtA:
undetectable		 3w9tE-4tqtA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		4 / 5 PHE A 365
GLY A  87
THR A 431
VAL A 395
 None
 1.08A 3wrkD-4tqtA:
undetectable		 3wrkD-4tqtA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		4 / 7 LEU A 265
ASP A 317
GLU A 186
HIS A 184
 None
ZN  A 501 (-2.8A)
None
ZN  A 502 (-3.3A)
 1.25A 4aq7A-4tqtA:
undetectable		 4aq7A-4tqtA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		4 / 7 ILE A 405
ASN A 417
GLU A 345
GLN A 443
 None
 0.97A 4g0vA-4tqtA:
undetectable		 4g0vA-4tqtA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		4 / 5 HIS A  61
HIS A 184
HIS A 240
ASP A 317
 ZN  A 501 (-3.4A)
ZN  A 502 (-3.3A)
ZN  A 502 (-3.5A)
ZN  A 501 (-2.8A)
 0.35A 4h9mA-4tqtA:
23.7		 4h9mA-4tqtA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		4 / 5 GLU A 186
ARG A 213
PRO A 291
SER A 242
 None
 1.25A 4k17B-4tqtA:
undetectable		 4k17B-4tqtA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_1
(MDR769 HIV-1
PROTEASE)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 11 GLY A 389
ALA A 390
ASP A 391
ASP A 393
THR A  17
 None
 1.04A 4l1aA-4tqtA:
undetectable		 4l1aA-4tqtA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_1
(MDR769 HIV-1
PROTEASE)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 11 GLY A 389
ALA A 390
ASP A 391
ASP A 393
THR A 371
 None
 0.98A 4l1aA-4tqtA:
undetectable		 4l1aA-4tqtA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		3 / 3 HIS A 209
TRP A 281
SER A 290
 None
 1.22A 4lrhD-4tqtA:
undetectable		 4lrhD-4tqtA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_2
(PROTEASE)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 9 GLY A 389
ALA A 390
ASP A 391
ASP A 393
THR A  17
 None
 1.10A 4njtD-4tqtA:
undetectable		 4njtD-4tqtA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA207_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 12 GLU A  29
ALA A   6
ALA A 392
GLY A 435
LEU A 432
 None
 1.10A 4oaeA-4tqtA:
undetectable		 4oaeA-4tqtA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA207_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 12 TYR A 416
ALA A 407
ALA A  83
ALA A 320
GLY A 341
 None
 1.09A 4oaeA-4tqtA:
undetectable		 4oaeA-4tqtA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 9 ALA A  82
THR A  81
GLY A  88
GLY A  87
ALA A  86
 None
 1.08A 4qvmK-4tqtA:
undetectable
4qvmL-4tqtA:
undetectable		 4qvmK-4tqtA:
17.94
4qvmL-4tqtA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 10 ALA A  82
THR A  81
GLY A  88
GLY A  87
ALA A  86
 None
 1.07A 4qw3K-4tqtA:
undetectable
4qw3L-4tqtA:
undetectable		 4qw3K-4tqtA:
17.74
4qw3L-4tqtA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 10 ALA A  82
THR A  81
GLY A  88
GLY A  87
ALA A  86
 None
 1.07A 4qw3Y-4tqtA:
undetectable
4qw3Z-4tqtA:
undetectable		 4qw3Y-4tqtA:
17.74
4qw3Z-4tqtA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UAC_A_ACRA501_2
(CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-))		 4tqt D-HYDANTOINASE
(Brucella
suis) 		4 / 7 GLU A 420
GLU A 344
ASP A 440
THR A 431
 None
 1.17A 4uacA-4tqtA:
undetectable		 4uacA-4tqtA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 6 HIS A  61
HIS A  63
HIS A 184
HIS A 240
ASP A 317
 ZN  A 501 (-3.4A)
ZN  A 501 (-3.3A)
ZN  A 502 (-3.3A)
ZN  A 502 (-3.5A)
ZN  A 501 (-2.8A)
 0.40A 4ubpC-4tqtA:
22.5		 4ubpC-4tqtA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		4 / 6 ASP A 393
ALA A 438
THR A  90
THR A 120
 None
 1.42A 4w5qA-4tqtA:
undetectable		 4w5qA-4tqtA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		3 / 3 ASP A  76
ARG A 119
PRO A 448
 None
 1.05A 4wanC-4tqtA:
undetectable		 4wanC-4tqtA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 12 THR A  79
ALA A  83
GLU A 344
LEU A  85
LEU A  64
 None
 1.30A 4xi3A-4tqtA:
undetectable		 4xi3A-4tqtA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 12 ILE A 414
GLY A 341
ALA A 320
ASP A  75
GLU A 345
 None
 1.26A 4xt8A-4tqtA:
1.8		 4xt8A-4tqtA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		4 / 6 ASP A 393
ALA A 438
THR A  90
THR A 120
 None
 1.48A 4z4iA-4tqtA:
undetectable		 4z4iA-4tqtA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 9 ALA A  82
THR A  81
GLY A  88
GLY A  87
ALA A  86
 None
 1.06A 5d0xK-4tqtA:
undetectable
5d0xL-4tqtA:
undetectable		 5d0xK-4tqtA:
17.74
5d0xL-4tqtA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 9 ALA A  82
THR A  81
GLY A  88
GLY A  87
ALA A  86
 None
 1.07A 5d0xY-4tqtA:
undetectable
5d0xZ-4tqtA:
undetectable		 5d0xY-4tqtA:
17.74
5d0xZ-4tqtA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_B_5OGB804_1
(HDAC6 PROTEIN)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 12 HIS A 240
HIS A  61
PHE A  95
LEU A 160
TYR A 156
 ZN  A 502 (-3.5A)
ZN  A 501 (-3.4A)
KCX  A 151 ( 3.7A)
None
None
 1.39A 5eenB-4tqtA:
undetectable		 5eenB-4tqtA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF8_B_LBHB2004_1
(HDAC6 PROTEIN)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 12 HIS A 240
HIS A  61
PHE A  95
LEU A 160
TYR A 156
 ZN  A 502 (-3.5A)
ZN  A 501 (-3.4A)
KCX  A 151 ( 3.7A)
None
None
 1.45A 5ef8B-4tqtA:
undetectable		 5ef8B-4tqtA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 11 ALA A  82
THR A  81
GLY A  88
GLY A  87
ALA A  86
 None
 1.01A 5lf3K-4tqtA:
undetectable
5lf3L-4tqtA:
undetectable		 5lf3K-4tqtA:
20.18
5lf3L-4tqtA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 11 ALA A  82
THR A  81
GLY A  88
GLY A  87
ALA A  86
 None
 1.01A 5lf3Y-4tqtA:
undetectable
5lf3Z-4tqtA:
undetectable		 5lf3Y-4tqtA:
20.18
5lf3Z-4tqtA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 12 GLY A 116
LYS A 117
ASP A  94
ASP A 317
ASP A  76
 None
None
None
ZN  A 501 (-2.8A)
None
 1.13A 5wwsB-4tqtA:
undetectable		 5wwsB-4tqtA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 4tqt D-HYDANTOINASE
(Brucella
suis) 		5 / 12 LEU A 377
ILE A 376
CYH A 313
LEU A 160
GLY A 262
 None
 1.16A 6a7pA-4tqtA:
undetectable		 6a7pA-4tqtA:
21.56