SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4tqv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 4tqv ALGM1
ALGM2
(Sphingomonas
sp.) 		5 / 12 PHE A 199
PHE A 142
TYR B 163
ALA B 199
LEU B 204
 None
 1.03A 1igxA-4tqvA:
undetectable		 1igxA-4tqvA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_C_DIFC2701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4tqv ALGM1
ALGM2
(Sphingomonas
sp.) 		5 / 12 LEU B 232
TYR B 213
VAL B 237
GLY A 150
ALA A 149
 None
 1.05A 1pxxC-4tqvB:
undetectable		 1pxxC-4tqvB:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_D_DIFD3701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4tqv ALGM1
ALGM2
(Sphingomonas
sp.) 		5 / 10 LEU B 232
TYR B 213
VAL B 237
GLY A 150
ALA A 149
 None
 1.04A 1pxxD-4tqvB:
undetectable		 1pxxD-4tqvB:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_1
(FATTY ACID-BINDING
PROTEIN)		 4tqv ALGM1
ALGS
(Sphingomonas
sp.;
Sphingomonas
sp.) 		3 / 3 TYR C  88
ARG A 226
GLN A 220
 None
 0.84A 1tw4A-4tqvC:
undetectable		 1tw4A-4tqvC:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4tqv ALGS
(Sphingomonas
sp.) 		4 / 7 HIS C  21
ASP C  15
THR C  17
TYR C  14
 None
 1.34A 1v54A-4tqvC:
undetectable
1v54C-4tqvC:
undetectable		 1v54A-4tqvC:
20.76
1v54C-4tqvC:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4tqv ALGS
(Sphingomonas
sp.) 		4 / 7 HIS C  21
ASP C  15
THR C  17
TYR C  14
 None
 1.32A 1v54N-4tqvC:
undetectable
1v54P-4tqvC:
undetectable		 1v54N-4tqvC:
20.76
1v54P-4tqvC:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4tqv ALGM1
ALGM2
(Sphingomonas
sp.;
Sphingomonas
sp.) 		5 / 12 VAL B  67
ASP B  70
SER B  76
GLY A 150
ILE A 145
 None
 1.42A 1xvaA-4tqvB:
undetectable		 1xvaA-4tqvB:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4tqv ALGM1
(Sphingomonas
sp.) 		4 / 8 TYR A 260
PHE A 258
THR A 272
PHE A 184
 None
 0.86A 1ykiA-4tqvA:
undetectable
1ykiB-4tqvA:
undetectable		 1ykiA-4tqvA:
22.01
1ykiB-4tqvA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4tqv ALGM1
(Sphingomonas
sp.) 		4 / 8 THR A 272
PHE A 184
TYR A 260
PHE A 258
 None
 0.84A 1ykiA-4tqvA:
undetectable
1ykiB-4tqvA:
undetectable		 1ykiA-4tqvA:
22.01
1ykiB-4tqvA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4tqv ALGM1
(Sphingomonas
sp.) 		4 / 8 TYR A 260
PHE A 258
THR A 272
PHE A 184
 None
 0.89A 1ykiC-4tqvA:
undetectable
1ykiD-4tqvA:
undetectable		 1ykiC-4tqvA:
22.01
1ykiD-4tqvA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4tqv ALGM1
(Sphingomonas
sp.) 		4 / 8 THR A 272
PHE A 184
TYR A 260
PHE A 258
 None
 0.84A 1ykiC-4tqvA:
undetectable
1ykiD-4tqvA:
undetectable		 1ykiC-4tqvA:
22.01
1ykiD-4tqvA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4tqv ALGS
(Sphingomonas
sp.) 		4 / 7 HIS C  21
ASP C  15
THR C  17
TYR C  14
 None
 1.35A 2dyrA-4tqvC:
undetectable
2dyrC-4tqvC:
undetectable		 2dyrA-4tqvC:
20.76
2dyrC-4tqvC:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4tqv ALGS
(Sphingomonas
sp.) 		4 / 7 HIS C  21
ASP C  15
THR C  17
TYR C  14
 None
 1.34A 2dyrN-4tqvC:
undetectable
2dyrP-4tqvC:
undetectable		 2dyrN-4tqvC:
20.76
2dyrP-4tqvC:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4tqv ALGS
(Sphingomonas
sp.) 		4 / 7 HIS C  21
ASP C  15
THR C  17
TYR C  14
 None
 1.33A 2eikN-4tqvC:
undetectable
2eikP-4tqvC:
undetectable		 2eikN-4tqvC:
20.76
2eikP-4tqvC:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_1
(PROTEASE)		 4tqv ALGM1
ALGM2
(Sphingomonas
sp.) 		5 / 12 ILE A 147
GLY A 150
VAL A 153
VAL B 259
ILE B 263
 None
 1.20A 2o4lA-4tqvA:
undetectable		 2o4lA-4tqvA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 4tqv ALGM1
ALGM2
(Sphingomonas
sp.) 		5 / 12 LEU B 102
ASN B 153
ILE A  46
PRO B  97
ILE B 157
 None
 0.98A 2pymA-4tqvB:
undetectable		 2pymA-4tqvB:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 4tqv ALGM2
(Sphingomonas
sp.) 		4 / 7 ILE B 236
TYR B 231
PHE B  73
ASP B  70
 None
 0.93A 2qebA-4tqvB:
undetectable		 2qebA-4tqvB:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 4tqv ALGM2
(Sphingomonas
sp.) 		4 / 7 ILE B 236
TYR B 231
PHE B  73
ASP B  70
 None
 0.92A 2qebB-4tqvB:
undetectable		 2qebB-4tqvB:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZE2_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 4tqv ALGM1
ALGM2
(Sphingomonas
sp.) 		5 / 10 ILE A 147
ASN B 211
VAL B 271
PRO B 227
LEU B 232
 None
 0.76A 2ze2A-4tqvA:
undetectable		 2ze2A-4tqvA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4tqv ALGS
(Sphingomonas
sp.) 		4 / 7 HIS C  21
ASP C  15
THR C  17
TYR C  14
 None
 1.31A 3abkA-4tqvC:
undetectable
3abkC-4tqvC:
undetectable		 3abkA-4tqvC:
20.76
3abkC-4tqvC:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4tqv ALGS
(Sphingomonas
sp.) 		4 / 7 HIS C  21
ASP C  15
THR C  17
TYR C  14
 None
 1.33A 3abkN-4tqvC:
undetectable
3abkP-4tqvC:
undetectable		 3abkN-4tqvC:
20.76
3abkP-4tqvC:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4tqv ALGS
(Sphingomonas
sp.) 		4 / 6 HIS C  21
ASP C  15
THR C  17
TYR C  14
 None
 1.31A 3ag1A-4tqvC:
undetectable
3ag1C-4tqvC:
undetectable		 3ag1A-4tqvC:
20.76
3ag1C-4tqvC:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4tqv ALGS
(Sphingomonas
sp.) 		4 / 6 HIS C  21
ASP C  15
THR C  17
TYR C  14
 None
 1.36A 3ag1N-4tqvC:
undetectable
3ag1P-4tqvC:
undetectable		 3ag1N-4tqvC:
20.76
3ag1P-4tqvC:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4tqv ALGS
(Sphingomonas
sp.) 		4 / 7 HIS C  21
ASP C  15
THR C  17
TYR C  14
 None
 1.33A 3ag4N-4tqvC:
undetectable
3ag4P-4tqvC:
undetectable		 3ag4N-4tqvC:
20.76
3ag4P-4tqvC:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4tqv ALGS
(Sphingomonas
sp.) 		4 / 6 HIS C  21
ASP C  15
THR C  17
TYR C  14
 None
 1.34A 3asnA-4tqvC:
undetectable
3asnC-4tqvC:
undetectable		 3asnA-4tqvC:
20.76
3asnC-4tqvC:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4tqv ALGM1
(Sphingomonas
sp.) 		4 / 6 ILE A 145
THR A 278
PHE A 184
TYR A 188
 None
 1.27A 3elzB-4tqvA:
undetectable		 3elzB-4tqvA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4tqv ALGS
(Sphingomonas
sp.) 		3 / 3 PRO C 226
LEU C 222
GLN C 215
 None
 0.68A 3hznG-4tqvC:
undetectable
3hznH-4tqvC:
undetectable		 3hznG-4tqvC:
22.71
3hznH-4tqvC:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_2
(HIV-1 PROTEASE)		 4tqv ALGM1
ALGM2
(Sphingomonas
sp.) 		5 / 11 ILE A 147
GLY A 150
VAL A 153
VAL B 259
ILE B 263
 None
 1.14A 3oxxB-4tqvA:
undetectable		 3oxxB-4tqvA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4tqv ALGM1
ALGM2
(Sphingomonas
sp.) 		5 / 12 PHE A 199
PHE A 142
TYR B 163
ALA B 199
LEU B 204
 None
 1.05A 4e1gA-4tqvA:
2.3		 4e1gA-4tqvA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4tqv ALGM1
ALGM2
(Sphingomonas
sp.) 		5 / 12 PHE A 199
PHE A 142
TYR B 163
ALA B 199
LEU B 204
 None
 1.02A 4e1gB-4tqvA:
undetectable		 4e1gB-4tqvA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOS_A_4KOA201_1
(UNCHARACTERIZED
PROTEIN)		 4tqv ALGM1
(Sphingomonas
sp.) 		5 / 12 PRO A 112
GLY A 104
ILE A 253
PHE A 111
LEU A 246
 None
 1.47A 4kosA-4tqvA:
undetectable		 4kosA-4tqvA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 4tqv ALGM1
(Sphingomonas
sp.) 		5 / 12 PRO A 112
GLY A 104
ILE A 253
PHE A 111
LEU A 246
 None
 1.50A 4kotA-4tqvA:
undetectable		 4kotA-4tqvA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4tqv ALGM1
ALGM2
(Sphingomonas
sp.) 		4 / 6 ILE B  36
ILE A 136
ILE B 268
LEU A 151
 None
 0.71A 4o8fB-4tqvB:
undetectable		 4o8fB-4tqvB:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA303_1
(CHITOSANASE)		 4tqv ALGM1
(Sphingomonas
sp.) 		4 / 6 GLU A 123
TYR A 216
ILE A 208
THR A 234
 None
 1.33A 4qwpA-4tqvA:
undetectable		 4qwpA-4tqvA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB302_1
(CHITOSANASE)		 4tqv ALGM1
(Sphingomonas
sp.) 		4 / 5 GLU A 123
TYR A 216
ILE A 208
THR A 234
 None
 1.30A 4qwpB-4tqvA:
undetectable		 4qwpB-4tqvA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		 4tqv ALGM2
(Sphingomonas
sp.) 		4 / 6 ASP B 136
LEU B 140
ILE B 128
PHE B 131
 None
 0.74A 4y4dA-4tqvB:
undetectable		 4y4dA-4tqvB:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4tqv ALGS
(Sphingomonas
sp.) 		4 / 7 HIS C  21
ASP C  15
THR C  17
TYR C  14
 None
 1.33A 5b1aN-4tqvC:
undetectable
5b1aP-4tqvC:
undetectable		 5b1aN-4tqvC:
20.76
5b1aP-4tqvC:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 4tqv ALGM1
ALGM2
(Sphingomonas
sp.) 		4 / 8 VAL A 203
ILE A 202
ILE B 207
PHE B 282
 None
 0.95A 5hw8H-4tqvA:
undetectable		 5hw8H-4tqvA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4tqv ALGS
(Sphingomonas
sp.) 		4 / 7 HIS C  21
ASP C  15
THR C  17
TYR C  14
 None
 1.33A 5iy5A-4tqvC:
undetectable
5iy5C-4tqvC:
undetectable		 5iy5A-4tqvC:
20.76
5iy5C-4tqvC:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4tqv ALGM1
ALGM2
(Sphingomonas
sp.) 		5 / 12 LEU B 232
TYR B 213
VAL B 237
GLY A 150
ALA A 149
 None
 1.06A 5jw1B-4tqvB:
undetectable		 5jw1B-4tqvB:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_A_ACTA1403_0
(L-THREONINE
3-DEHYDROGENASE)		 4tqv ALGM2
(Sphingomonas
sp.) 		4 / 5 MET B  39
SER B  42
GLY B  44
ALA B  46
 None
 1.05A 5k50A-4tqvB:
undetectable		 5k50A-4tqvB:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4tqv ALGM1
ALGM2
(Sphingomonas
sp.) 		5 / 12 LEU B 232
TYR B 213
VAL B 237
GLY A 150
ALA A 149
 None
 1.04A 5kirA-4tqvB:
undetectable		 5kirA-4tqvB:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 4tqv ALGS
(Sphingomonas
sp.) 		4 / 6 ASP C  95
ASP C 134
ARG C 140
ASN C  96
 None
 1.22A 5l6eA-4tqvC:
undetectable		 5l6eA-4tqvC:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 4tqv ALGM1
(Sphingomonas
sp.) 		4 / 7 TYR A 204
ILE A 238
ILE A 208
ILE A 230
 None
 0.88A 5murB-4tqvA:
2.4		 5murB-4tqvA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4tqv ALGS
(Sphingomonas
sp.) 		4 / 6 HIS C  21
ASP C  15
THR C  17
TYR C  14
 None
 1.35A 5x19N-4tqvC:
undetectable
5x19P-4tqvC:
undetectable		 5x19N-4tqvC:
20.76
5x19P-4tqvC:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 4tqv ALGS
(Sphingomonas
sp.) 		4 / 5 HIS C 345
ALA C 299
SER C 296
GLY C 295
 None
 1.25A 5yodD-4tqvC:
undetectable		 5yodD-4tqvC:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4tqv ALGS
(Sphingomonas
sp.) 		4 / 7 HIS C  21
ASP C  15
THR C  17
TYR C  14
 None
 1.34A 5zcqN-4tqvC:
undetectable
5zcqP-4tqvC:
undetectable		 5zcqN-4tqvC:
20.76
5zcqP-4tqvC:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_1
(CYTOCHROME P450 1A1)		 4tqv ALGM2
(Sphingomonas
sp.) 		4 / 5 ILE B 167
SER B 166
ALA B  99
LEU B 186
 None
 1.03A 6dwnA-4tqvB:
undetectable		 6dwnA-4tqvB:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4tqv ALGS
(Sphingomonas
sp.) 		4 / 6 HIS C  21
ASP C  15
THR C  17
TYR C  14
 None
 1.38A 6nmpA-4tqvC:
undetectable
6nmpC-4tqvC:
undetectable		 6nmpA-4tqvC:
20.76
6nmpC-4tqvC:
23.32