SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4tt6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)		 4tt6 ATPASE FAMILY AAA
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		5 / 11 ILE A1056
ALA A1080
LEU A1081
THR A1084
LEU A1031
 None
 1.15A 4g1bB-4tt6A:
2.8		 4g1bB-4tt6A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 4tt6 ATPASE FAMILY AAA
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		4 / 6 VAL A1013
VAL A1018
TYR A1021
ILE A1074
 None
 0.84A 5pbeA-4tt6A:
15.2		 5pbeA-4tt6A:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 4tt6 ATPASE FAMILY AAA
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		5 / 12 ASP A1030
LEU A1031
ASP A1039
LEU A1040
THR A 997
 None
 1.17A 6b54A-4tt6A:
undetectable		 6b54A-4tt6A:
20.48