SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ttw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_A_RBFA296_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 4ttw CENTRIOLE PROTEIN
(Chlamydomonas
reinhardtii) 		5 / 11 VAL A  29
VAL A  31
GLU A 111
LEU A 109
ILE A 139
 None
 1.37A 1t6zA-4ttwA:
undetectable		 1t6zA-4ttwA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4ttw CENTRIOLE PROTEIN
(Chlamydomonas
reinhardtii) 		5 / 9 LEU A 153
ILE A  67
PHE A 137
LEU A 110
ILE A 106
 None
 1.27A 2f78B-4ttwA:
undetectable		 2f78B-4ttwA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4ttw CENTRIOLE PROTEIN
(Chlamydomonas
reinhardtii) 		5 / 9 LEU A 153
ILE A  67
PHE A 137
LEU A 110
ILE A 106
 None
 1.25A 2f7aA-4ttwA:
undetectable		 2f7aA-4ttwA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA802_1
(TRANSPORTER)		 4ttw CENTRIOLE PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 7 ILE A 106
ARG A  27
PHE A  47
PHE A 137
 None
 1.10A 2q6hA-4ttwA:
undetectable		 2q6hA-4ttwA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 4ttw CENTRIOLE PROTEIN
(Chlamydomonas
reinhardtii) 		4 / 7 ILE A 106
ARG A  27
PHE A  47
PHE A 137
 None
 1.10A 2qb4A-4ttwA:
undetectable		 2qb4A-4ttwA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 4ttw CENTRIOLE PROTEIN
(Chlamydomonas
reinhardtii) 		3 / 3 LYS A  34
VAL A 127
HIS A  32
 None
 1.11A 3tj7A-4ttwA:
undetectable		 3tj7A-4ttwA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 4ttw CENTRIOLE PROTEIN
(Chlamydomonas
reinhardtii) 		5 / 10 LEU A 128
VAL A  29
ILE A 106
LEU A 110
PRO A  28
 None
 1.19A 5ienB-4ttwA:
undetectable		 5ienB-4ttwA:
26.35