SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4tuf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13GS_A_SASA211_1
(GLUTATHIONE
S-TRANSFERASE)		 4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE
(Xanthomonas
campestris) 		5 / 10 TYR A 263
PHE A 236
ILE A 143
PRO A 260
GLY A 238
 None
 1.26A 13gsA-4tufA:
undetectable		 13gsA-4tufA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A27_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE
(Xanthomonas
campestris) 		5 / 12 LEU A  62
ASN A 105
TYR A 102
VAL A 120
PHE A  52
 None
 1.30A 1a27A-4tufA:
2.0		 1a27A-4tufA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE
(Xanthomonas
campestris) 		4 / 6 PHE A  52
LEU A 133
VAL A 174
VAL A 120
 None
 0.99A 1e7aB-4tufA:
undetectable		 1e7aB-4tufA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE
(Xanthomonas
campestris) 		4 / 7 LYS A  45
LEU A  44
GLN A  43
LEU A 175
 None
 1.00A 1v55C-4tufA:
undetectable
1v55J-4tufA:
undetectable		 1v55C-4tufA:
21.01
1v55J-4tufA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE
(Xanthomonas
campestris) 		4 / 8 ASP A 320
LYS A 316
PHE A 273
ASP A 275
 None
 0.97A 2aouA-4tufA:
1.4		 2aouA-4tufA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE
(Xanthomonas
campestris) 		4 / 8 LYS A  45
LEU A  44
GLN A  43
LEU A 175
 None
 0.92A 2dyrP-4tufA:
undetectable
2dyrW-4tufA:
undetectable		 2dyrP-4tufA:
21.01
2dyrW-4tufA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE
(Xanthomonas
campestris) 		4 / 7 LYS A  45
LEU A  44
GLN A  43
LEU A 175
 None
 1.01A 2eijC-4tufA:
undetectable
2eijJ-4tufA:
undetectable		 2eijC-4tufA:
21.01
2eijJ-4tufA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE
(Xanthomonas
campestris) 		4 / 8 LYS A  45
LEU A  44
GLN A  43
LEU A 175
 None
 0.93A 2eikP-4tufA:
undetectable
2eikW-4tufA:
undetectable		 2eikP-4tufA:
21.01
2eikW-4tufA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE
(Xanthomonas
campestris) 		4 / 7 LYS A  45
LEU A  44
GLN A  43
LEU A 175
 None
 1.00A 2eimC-4tufA:
undetectable
2eimJ-4tufA:
undetectable		 2eimC-4tufA:
21.01
2eimJ-4tufA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE
(Xanthomonas
campestris) 		4 / 7 LYS A  45
LEU A  44
GLN A  43
LEU A 175
 None
 1.00A 2einC-4tufA:
undetectable
2einJ-4tufA:
undetectable		 2einC-4tufA:
21.01
2einJ-4tufA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE
(Xanthomonas
campestris) 		6 / 12 ASN A 181
GLU A 182
HIS A 261
TYR A 263
GLU A 303
TRP A 337
 None
 0.89A 2v3dA-4tufA:
7.3		 2v3dA-4tufA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE
(Xanthomonas
campestris) 		5 / 12 VAL A 120
THR A  54
SER A  99
PHE A  52
HIS A  60
 None
 1.32A 2vdyA-4tufA:
undetectable		 2vdyA-4tufA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE
(Xanthomonas
campestris) 		4 / 4 ARG A 167
ASP A 139
GLY A  55
THR A  95
 None
2HP  A 406 (-2.9A)
None
None
 1.17A 3k4vB-4tufA:
undetectable		 3k4vB-4tufA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA271_0
(PROTEIN SSM1)		 4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE
(Xanthomonas
campestris) 		4 / 5 GLY A 222
GLU A 221
GLY A 239
PRO A 183
 None
 0.85A 3onnA-4tufA:
undetectable		 3onnA-4tufA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE
(Xanthomonas
campestris) 		5 / 12 LEU A 258
GLY A 239
HIS A 289
ALA A 187
PRO A 243
 None
 1.32A 3tm4A-4tufA:
undetectable		 3tm4A-4tufA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE
(Xanthomonas
campestris) 		3 / 3 ASN A  48
TRP A 337
ASP A 178
 None
 1.21A 4a7tA-4tufA:
undetectable
4a7tF-4tufA:
undetectable		 4a7tA-4tufA:
18.29
4a7tF-4tufA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_A_BEZA1000_0
(BENZOATE-COENZYME A
LIGASE)		 4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE
(Xanthomonas
campestris) 		4 / 7 ALA A 294
GLY A 295
GLY A 330
ILE A 331
 None
 0.63A 4eatA-4tufA:
undetectable		 4eatA-4tufA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE
(Xanthomonas
campestris) 		3 / 3 HIS A  60
TRP A 337
SER A  99
 None
 1.21A 4lrhD-4tufA:
undetectable		 4lrhD-4tufA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE
(Xanthomonas
campestris) 		4 / 6 ARG A 358
ASP A 266
GLY A 311
ASP A 315
 None
 0.93A 5hp1A-4tufA:
undetectable		 5hp1A-4tufA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND3_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE
(Xanthomonas
campestris) 		5 / 12 ASP A 134
GLU A 303
LEU A 249
LEU A 258
ALA A 259
 None
 1.15A 5nd3B-4tufA:
undetectable		 5nd3B-4tufA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_A_P2EA1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 4tuf MAJOR EXTRACELLULAR
ENDOGLUCANASE
(Xanthomonas
campestris) 		4 / 4 PRO A 341
MET A  74
GLY A  78
VAL A  47
 None
 1.46A 6ak3A-4tufA:
undetectable		 6ak3A-4tufA:
14.29