SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4tvc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 12 TYR A2650
LEU A2166
LEU A2167
ASP A2210
ALA A2211
 GOL  A3008 (-3.3A)
None
None
GOL  A3008 (-2.7A)
GOL  A3008 ( 3.8A)
 0.70A 1dedA-4tvcA:
6.5		 1dedA-4tvcA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		7 / 12 TYR A2650
ARG A2208
ASP A2210
ALA A2211
GLU A2248
HIS A2321
ASP A2322
 GOL  A3008 (-3.3A)
None
GOL  A3008 (-2.7A)
GOL  A3008 ( 3.8A)
GOL  A3008 ( 4.5A)
None
None
 0.90A 1dedB-4tvcA:
7.7		 1dedB-4tvcA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 6 ASN A2543
ILE A2372
SER A2374
THR A2499
 None
 1.17A 1h7xA-4tvcA:
3.2		 1h7xA-4tvcA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 6 ASN A2543
ILE A2372
SER A2374
THR A2499
 None
 1.18A 1h7xB-4tvcA:
3.4		 1h7xB-4tvcA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 6 ASN A2543
ILE A2372
SER A2374
THR A2499
 None
 1.18A 1h7xC-4tvcA:
2.1		 1h7xC-4tvcA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 6 ASN A2543
ILE A2372
SER A2374
THR A2499
 None
 1.18A 1h7xD-4tvcA:
3.7		 1h7xD-4tvcA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 6 TYR A2391
ASN A2615
TYR A2401
TYR A2395
 None
 1.30A 1kiaA-4tvcA:
undetectable		 1kiaA-4tvcA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_ACTB1294_0
(GLYCINE
N-METHYLTRANSFERASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 6 TYR A2391
ASN A2615
TYR A2401
TYR A2395
 None
 1.30A 1kiaB-4tvcA:
undetectable		 1kiaB-4tvcA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_ACTC2294_0
(GLYCINE
N-METHYLTRANSFERASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 7 TYR A2391
ASN A2615
TYR A2401
TYR A2395
 None
 1.30A 1kiaC-4tvcA:
undetectable		 1kiaC-4tvcA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_ACTD3294_0
(GLYCINE
N-METHYLTRANSFERASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 7 TYR A2391
ASN A2615
TYR A2401
TYR A2395
 None
 1.29A 1kiaD-4tvcA:
undetectable		 1kiaD-4tvcA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 8 THR A2303
ASP A2301
MET A2429
LEU A2437
 None
 1.02A 1lhvA-4tvcA:
undetectable		 1lhvA-4tvcA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 6 TYR A2391
ASN A2615
TYR A2401
TYR A2395
 None
 1.30A 1nbhA-4tvcA:
undetectable		 1nbhA-4tvcA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_ACTB1294_0
(GLYCINE
N-METHYLTRANSFERASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 7 TYR A2391
ASN A2615
TYR A2401
TYR A2395
 None
 1.29A 1nbhB-4tvcA:
undetectable		 1nbhB-4tvcA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_ACTC2294_0
(GLYCINE
N-METHYLTRANSFERASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 6 TYR A2391
ASN A2615
TYR A2401
TYR A2395
 None
 1.29A 1nbhC-4tvcA:
undetectable		 1nbhC-4tvcA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_ACTD3294_0
(GLYCINE
N-METHYLTRANSFERASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 7 TYR A2391
ASN A2615
TYR A2401
TYR A2395
 None
 1.30A 1nbhD-4tvcA:
undetectable		 1nbhD-4tvcA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		3 / 3 ASP A2689
HIS A2321
ASP A2643
 None
None
GOL  A3008 (-2.6A)
 0.85A 1nw5A-4tvcA:
undetectable		 1nw5A-4tvcA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 8 TYR A2409
TRP A2622
LEU A2380
MET A2416
 None
 1.46A 1uw6A-4tvcA:
undetectable
1uw6B-4tvcA:
undetectable		 1uw6A-4tvcA:
12.00
1uw6B-4tvcA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 8 TYR A2743
THR A2196
TYR A2739
LEU A2658
 None
 1.35A 1uw6A-4tvcA:
undetectable
1uw6B-4tvcA:
undetectable		 1uw6A-4tvcA:
12.00
1uw6B-4tvcA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 8 TYR A2409
TRP A2622
LEU A2380
MET A2416
 None
 1.46A 1uw6D-4tvcA:
undetectable
1uw6E-4tvcA:
undetectable		 1uw6D-4tvcA:
12.00
1uw6E-4tvcA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 8 TYR A2743
THR A2196
TYR A2739
LEU A2658
 None
 1.33A 1uw6D-4tvcA:
undetectable
1uw6E-4tvcA:
undetectable		 1uw6D-4tvcA:
12.00
1uw6E-4tvcA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 8 TYR A2409
TRP A2622
LEU A2380
MET A2416
 None
 1.47A 1uw6G-4tvcA:
undetectable
1uw6H-4tvcA:
undetectable		 1uw6G-4tvcA:
12.00
1uw6H-4tvcA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 8 TYR A2743
THR A2196
TYR A2739
LEU A2658
 None
 1.33A 1uw6G-4tvcA:
undetectable
1uw6H-4tvcA:
undetectable		 1uw6G-4tvcA:
12.00
1uw6H-4tvcA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 8 TYR A2409
TRP A2622
LEU A2380
MET A2416
 None
 1.46A 1uw6P-4tvcA:
undetectable
1uw6Q-4tvcA:
undetectable		 1uw6P-4tvcA:
12.00
1uw6Q-4tvcA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 8 TYR A2743
THR A2196
TYR A2739
LEU A2658
 None
 1.32A 1uw6P-4tvcA:
undetectable
1uw6Q-4tvcA:
undetectable		 1uw6P-4tvcA:
12.00
1uw6Q-4tvcA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 8 LEU A2658
TYR A2743
THR A2196
TYR A2739
 None
 1.33A 1uw6P-4tvcA:
undetectable
1uw6T-4tvcA:
undetectable		 1uw6P-4tvcA:
12.00
1uw6T-4tvcA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 8 TRP A2622
LEU A2380
MET A2416
TYR A2409
 None
 1.47A 1uw6P-4tvcA:
undetectable
1uw6T-4tvcA:
undetectable		 1uw6P-4tvcA:
12.00
1uw6T-4tvcA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		3 / 3 PHE A1966
TYR A1893
TYR A1974
 None
 0.99A 1x70B-4tvcA:
undetectable		 1x70B-4tvcA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_D_NCAD510_0
(NAD-DEPENDENT
DEACETYLASE 2)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 5 ALA A1802
PHE A1816
ILE A1809
ASP A2073
 None
None
None
TYI  A2075 (-3.9A)
 1.15A 1yc2D-4tvcA:
undetectable		 1yc2D-4tvcA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 8 TYR A2357
TYR A2390
HIS A2319
GLY A2324
 None
 0.85A 2ha4A-4tvcA:
2.1		 2ha4A-4tvcA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 7 TYR A2357
TYR A2390
HIS A2319
GLY A2324
 None
 0.84A 2ha4B-4tvcA:
undetectable		 2ha4B-4tvcA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 11 TYR A2650
ASP A2210
HIS A2321
ASP A2322
ASN A2596
 GOL  A3008 (-3.3A)
GOL  A3008 (-2.7A)
None
None
None
 1.29A 2owcA-4tvcA:
2.2		 2owcA-4tvcA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 8 ASN A2123
TYR A2128
PHE A1976
ASN A2045
 None
 1.19A 2wekA-4tvcA:
2.2		 2wekA-4tvcA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 8 ASN A2123
TYR A2128
PHE A1976
ASN A2045
 None
 1.21A 2wekB-4tvcA:
1.6		 2wekB-4tvcA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 4 ARG A2388
GLY A2593
GLU A2628
SER A2406
 None
 1.40A 2xctS-4tvcA:
undetectable
2xctU-4tvcA:
undetectable		 2xctS-4tvcA:
20.75
2xctU-4tvcA:
20.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		8 / 12 LEU A2166
ALA A2211
GLU A2248
ARG A2269
HIS A2321
ASP A2322
ASP A2643
GLN A2694
 None
GOL  A3008 ( 3.8A)
GOL  A3008 ( 4.5A)
None
None
None
GOL  A3008 (-2.6A)
GOL  A3008 (-3.2A)
 0.75A 3aicA-4tvcA:
48.8		 3aicA-4tvcA:
38.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		9 / 12 LEU A2166
ARG A2208
ASP A2210
ALA A2211
GLU A2248
HIS A2321
ASP A2322
ASP A2643
GLN A2694
 None
None
GOL  A3008 (-2.7A)
GOL  A3008 ( 3.8A)
GOL  A3008 ( 4.5A)
None
None
GOL  A3008 (-2.6A)
GOL  A3008 (-3.2A)
 0.34A 3aicA-4tvcA:
48.8		 3aicA-4tvcA:
38.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		6 / 12 LEU A2167
ARG A2208
ASP A2210
HIS A2321
ASP A2322
GLN A2694
 None
None
GOL  A3008 (-2.7A)
None
None
GOL  A3008 (-3.2A)
 1.32A 3aicA-4tvcA:
48.8		 3aicA-4tvcA:
38.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		7 / 12 LEU A2166
ALA A2211
GLU A2248
ARG A2269
ASP A2322
ASP A2643
GLN A2694
 None
GOL  A3008 ( 3.8A)
GOL  A3008 ( 4.5A)
None
None
GOL  A3008 (-2.6A)
GOL  A3008 (-3.2A)
 0.81A 3aicB-4tvcA:
48.4		 3aicB-4tvcA:
38.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		9 / 12 LEU A2166
ARG A2208
ASP A2210
ALA A2211
GLU A2248
HIS A2321
ASP A2322
ASP A2643
GLN A2694
 None
None
GOL  A3008 (-2.7A)
GOL  A3008 ( 3.8A)
GOL  A3008 ( 4.5A)
None
None
GOL  A3008 (-2.6A)
GOL  A3008 (-3.2A)
 0.34A 3aicB-4tvcA:
48.4		 3aicB-4tvcA:
38.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		9 / 12 ARG A2208
ASP A2210
ALA A2211
GLU A2248
HIS A2321
ASP A2322
ASP A2643
TYR A2650
GLN A2694
 None
GOL  A3008 (-2.7A)
GOL  A3008 ( 3.8A)
GOL  A3008 ( 4.5A)
None
None
GOL  A3008 (-2.6A)
GOL  A3008 (-3.3A)
GOL  A3008 (-3.2A)
 0.27A 3aicC-4tvcA:
49.4		 3aicC-4tvcA:
38.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		9 / 12 LEU A2166
ARG A2208
ALA A2211
GLU A2248
ARG A2269
HIS A2321
ASP A2322
ASP A2643
GLN A2694
 None
None
GOL  A3008 ( 3.8A)
GOL  A3008 ( 4.5A)
None
None
None
GOL  A3008 (-2.6A)
GOL  A3008 (-3.2A)
 0.69A 3aicD-4tvcA:
49.4		 3aicD-4tvcA:
38.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		9 / 12 LEU A2166
ARG A2208
ASP A2210
ALA A2211
GLU A2248
HIS A2321
ASP A2322
ASP A2643
GLN A2694
 None
None
GOL  A3008 (-2.7A)
GOL  A3008 ( 3.8A)
GOL  A3008 ( 4.5A)
None
None
GOL  A3008 (-2.6A)
GOL  A3008 (-3.2A)
 0.34A 3aicD-4tvcA:
49.4		 3aicD-4tvcA:
38.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		6 / 12 LEU A2167
ARG A2208
ASP A2210
HIS A2321
ASP A2322
GLN A2694
 None
None
GOL  A3008 (-2.7A)
None
None
GOL  A3008 (-3.2A)
 1.35A 3aicD-4tvcA:
49.4		 3aicD-4tvcA:
38.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		10 / 12 LEU A2166
ARG A2208
ASP A2210
ALA A2211
GLU A2248
ARG A2269
HIS A2321
ASP A2322
ASP A2643
GLN A2694
 None
None
GOL  A3008 (-2.7A)
GOL  A3008 ( 3.8A)
GOL  A3008 ( 4.5A)
None
None
None
GOL  A3008 (-2.6A)
GOL  A3008 (-3.2A)
 0.65A 3aicE-4tvcA:
49.4		 3aicE-4tvcA:
38.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		6 / 12 LEU A2167
ARG A2208
ASP A2210
ARG A2269
HIS A2321
ASP A2322
 None
None
GOL  A3008 (-2.7A)
None
None
None
 1.43A 3aicE-4tvcA:
49.4		 3aicE-4tvcA:
38.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		8 / 12 LEU A2166
ALA A2211
GLU A2248
ARG A2269
HIS A2321
ASP A2322
ASP A2643
GLN A2694
 None
GOL  A3008 ( 3.8A)
GOL  A3008 ( 4.5A)
None
None
None
GOL  A3008 (-2.6A)
GOL  A3008 (-3.2A)
 0.78A 3aicF-4tvcA:
48.8		 3aicF-4tvcA:
38.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		9 / 12 LEU A2166
ARG A2208
ASP A2210
ALA A2211
GLU A2248
HIS A2321
ASP A2322
ASP A2643
GLN A2694
 None
None
GOL  A3008 (-2.7A)
GOL  A3008 ( 3.8A)
GOL  A3008 ( 4.5A)
None
None
GOL  A3008 (-2.6A)
GOL  A3008 (-3.2A)
 0.36A 3aicF-4tvcA:
48.8		 3aicF-4tvcA:
38.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		9 / 12 LEU A2166
ARG A2208
ALA A2211
GLU A2248
ARG A2269
HIS A2321
ASP A2322
ASP A2643
GLN A2694
 None
None
GOL  A3008 ( 3.8A)
GOL  A3008 ( 4.5A)
None
None
None
GOL  A3008 (-2.6A)
GOL  A3008 (-3.2A)
 0.73A 3aicG-4tvcA:
49.5		 3aicG-4tvcA:
38.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		9 / 12 LEU A2166
ARG A2208
ASP A2210
ALA A2211
GLU A2248
HIS A2321
ASP A2322
ASP A2643
GLN A2694
 None
None
GOL  A3008 (-2.7A)
GOL  A3008 ( 3.8A)
GOL  A3008 ( 4.5A)
None
None
GOL  A3008 (-2.6A)
GOL  A3008 (-3.2A)
 0.33A 3aicG-4tvcA:
49.5		 3aicG-4tvcA:
38.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		9 / 12 LEU A2166
ARG A2208
ASP A2210
ALA A2211
GLU A2248
HIS A2321
ASP A2322
ASP A2643
GLN A2694
 None
None
GOL  A3008 (-2.7A)
GOL  A3008 ( 3.8A)
GOL  A3008 ( 4.5A)
None
None
GOL  A3008 (-2.6A)
GOL  A3008 (-3.2A)
 0.32A 3aicH-4tvcA:
49.3		 3aicH-4tvcA:
38.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		7 / 12 LEU A2166
GLU A2248
ARG A2269
HIS A2321
ASP A2322
ASP A2643
GLN A2694
 None
GOL  A3008 ( 4.5A)
None
None
None
GOL  A3008 (-2.6A)
GOL  A3008 (-3.2A)
 0.77A 3aicH-4tvcA:
49.3		 3aicH-4tvcA:
38.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 12 LEU A2167
ARG A2208
ASP A2210
HIS A2321
ASP A2322
 None
None
GOL  A3008 (-2.7A)
None
None
 0.96A 3aicH-4tvcA:
49.3		 3aicH-4tvcA:
38.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 11 LEU A2462
GLY A2463
ILE A2465
SER A2430
THR A2428
 None
 1.28A 3bjwB-4tvcA:
undetectable		 3bjwB-4tvcA:
7.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 11 LEU A2462
GLY A2463
ILE A2465
SER A2430
THR A2428
 None
 1.22A 3bjwH-4tvcA:
undetectable		 3bjwH-4tvcA:
7.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		3 / 3 GLY A2461
GLY A2425
GLY A2443
 None
 0.40A 3bogD-4tvcA:
undetectable		 3bogD-4tvcA:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_PNTA901_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 12 TYR A2812
THR A2013
ASP A2012
GLY A2700
SER A2729
 None
 1.49A 3hiiA-4tvcA:
0.9		 3hiiA-4tvcA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_PNTB901_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 12 TYR A2812
THR A2013
ASP A2012
GLY A2700
SER A2729
 None
 1.48A 3hiiB-4tvcA:
undetectable		 3hiiB-4tvcA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IXL_A_PACA5000_0
(ARYLMALONATE
DECARBOXYLASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 10 THR A2428
SER A2439
VAL A2423
GLY A2426
GLY A2425
 None
 1.30A 3ixlA-4tvcA:
undetectable		 3ixlA-4tvcA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 8 THR A2223
LEU A2227
ALA A2262
SER A2245
 None
 0.91A 3kp6A-4tvcA:
undetectable		 3kp6A-4tvcA:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 8 TYR A1909
VAL A1935
GLY A1907
GLY A1933
 None
 0.81A 3n9jB-4tvcA:
undetectable		 3n9jB-4tvcA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_I_SAMI228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 12 GLY A2485
ALA A2449
THR A2428
ASP A2483
GLN A2520
 None
 0.96A 3nvkI-4tvcA:
undetectable		 3nvkI-4tvcA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		3 / 3 THR A2223
ASP A2692
GLU A2181
 None
 0.66A 3qowA-4tvcA:
2.2		 3qowA-4tvcA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_D_EVPD1_1
(DNA TOPOISOMERASE
2-BETA)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 5 GLY A2732
ASP A2654
ARG A2655
GLN A2742
 None
 1.33A 3qx3B-4tvcA:
undetectable		 3qx3B-4tvcA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 12 PHE A2641
LEU A2166
PHE A2214
VAL A2711
GLU A2327
 None
None
None
IYR  A2712 ( 3.0A)
None
 1.19A 4fiaA-4tvcA:
undetectable		 4fiaA-4tvcA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 12 PHE A2641
LEU A2166
PHE A2214
VAL A2711
GLU A2327
 None
None
None
IYR  A2712 ( 3.0A)
None
 1.19A 4fiaA-4tvcA:
undetectable		 4fiaA-4tvcA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 8 PRO A2159
ASP A2164
LYS A2142
ALA A2709
 None
 1.06A 4k0bB-4tvcA:
undetectable		 4k0bB-4tvcA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 12 VAL A1902
TYR A1893
SER A1896
GLY A1899
THR A1977
 None
 1.20A 4mm4A-4tvcA:
undetectable		 4mm4A-4tvcA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 12 VAL A1902
TYR A1893
SER A1896
GLY A1899
THR A1977
 None
 1.24A 4mm6A-4tvcA:
undetectable		 4mm6A-4tvcA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM7_A_29JA603_1
(TRANSPORTER)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 10 VAL A1902
TYR A1893
SER A1896
GLY A1899
THR A1977
 None
 1.21A 4mm7A-4tvcA:
undetectable		 4mm7A-4tvcA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 4 ASN A1946
GLY A1933
ASP A1888
ASP A1960
 None
 1.20A 4n49A-4tvcA:
undetectable		 4n49A-4tvcA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_A_SAMA301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 12 GLN A1942
LEU A1941
GLY A1907
ASP A1925
ALA A1906
 GLC  A3005 (-3.4A)
None
None
None
None
 1.17A 4pclA-4tvcA:
undetectable		 4pclA-4tvcA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 7 PHE A2594
GLN A2598
THR A2608
ILE A2612
 None
 0.96A 4pcuA-4tvcA:
undetectable		 4pcuA-4tvcA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 5 THR A1798
THR A1797
THR A1979
HIS A2818
 None
TYI  A2075 ( 4.8A)
None
None
 1.29A 4pgfB-4tvcA:
undetectable		 4pgfB-4tvcA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 5 THR A2571
THR A2570
THR A2566
ASN A2309
 None
 1.26A 4pgfB-4tvcA:
undetectable		 4pgfB-4tvcA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE0_A_40LA1101_0
(PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 12 MET A2289
TYR A2376
THR A2277
ASN A2278
ILE A2318
 None
 1.35A 4xe0A-4tvcA:
2.3		 4xe0A-4tvcA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 6 LYS A2793
GLY A2733
GLY A2732
ASP A2654
 None
 0.90A 5a06D-4tvcA:
undetectable		 5a06D-4tvcA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 5 TYR A2188
GLY A2659
TYR A2735
GLY A2733
 None
 1.07A 5ayfA-4tvcA:
undetectable		 5ayfA-4tvcA:
12.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 12 ARG A2208
ASP A2210
GLU A2248
HIS A2321
ASP A2322
 None
GOL  A3008 (-2.7A)
GOL  A3008 ( 4.5A)
None
None
 0.79A 5csyB-4tvcA:
3.2		 5csyB-4tvcA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		3 / 3 THR A2223
ASP A2692
GLU A2181
 None
 0.79A 5fa8A-4tvcA:
undetectable		 5fa8A-4tvcA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_A_C2FA402_0
(THYMIDYLATE SYNTHASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 11 ILE A2466
LEU A2290
ASP A2432
LEU A2436
GLY A2435
 None
 1.35A 5fctA-4tvcA:
undetectable		 5fctA-4tvcA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 12 ALA A2651
GLY A2649
GLY A2637
SER A2636
LEU A2698
 None
 0.98A 5gwxA-4tvcA:
undetectable		 5gwxA-4tvcA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 6 PHE A2652
VAL A2695
ALA A2651
THR A2640
 None
 1.16A 5t7bA-4tvcA:
undetectable		 5t7bA-4tvcA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 5 ASN A2693
ASP A2170
ASN A2801
ASN A2182
 CA  A3000 (-3.1A)
CA  A3000 (-2.2A)
None
None
 1.40A 5vooE-4tvcA:
3.0		 5vooE-4tvcA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 7 GLY A2809
GLY A2811
GLU A2127
ASN A2804
 None
 0.79A 5ybbB-4tvcA:
undetectable		 5ybbB-4tvcA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 5 GLY A2732
ASP A2654
ARG A2655
GLN A2742
 None
 1.50A 5zrfB-4tvcA:
undetectable		 5zrfB-4tvcA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7J_A_TESA502_0
(CYTOCHROME P450)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 7 LEU A2378
LEU A2268
ALA A2271
ALA A2272
 None
 0.81A 6a7jA-4tvcA:
undetectable		 6a7jA-4tvcA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 12 TYR A2650
LEU A2166
ASP A2210
HIS A2321
ASP A2322
 GOL  A3008 (-3.3A)
None
GOL  A3008 (-2.7A)
None
None
 0.71A 6ag0A-4tvcA:
11.2		 6ag0A-4tvcA:
5.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 12 PHE A2525
LEU A2472
GLY A2540
VAL A2552
ARG A2539
 None
 1.34A 6bxnB-4tvcA:
undetectable		 6bxnB-4tvcA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_1
(STIE PROTEIN)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		4 / 5 ARG A2539
THR A2514
GLN A2533
ASP A2510
 None
 1.50A 6ectA-4tvcA:
undetectable		 6ectA-4tvcA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_B_FFOB403_0
(THYMIDYLATE SYNTHASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 10 ILE A2466
LEU A2290
ASP A2432
LEU A2436
GLY A2435
 None
 1.44A 6r2eB-4tvcA:
undetectable		 6r2eB-4tvcA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_C_FFOC404_0
(THYMIDYLATE SYNTHASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 10 ILE A2466
LEU A2290
ASP A2432
LEU A2436
GLY A2435
 None
 1.45A 6r2eC-4tvcA:
undetectable		 6r2eC-4tvcA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_D_FFOD403_0
(THYMIDYLATE SYNTHASE)		 4tvc DEXTRANSUCRASE
(Leuconostoc
mesenteroides) 		5 / 10 ILE A2466
LEU A2290
ASP A2432
LEU A2436
GLY A2435
 None
 1.46A 6r2eD-4tvcA:
undetectable		 6r2eD-4tvcA:
14.76