SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4tx7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		4 / 7 SER A 164
TYR A 167
ASN A 166
TYR A 169
 None
 1.05A 1dssG-4tx7A:
undetectable		 1dssG-4tx7A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		3 / 3 ALA A 198
THR A 109
PHE A  86
 None
 0.64A 2c6nB-4tx7A:
undetectable		 2c6nB-4tx7A:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		5 / 12 VAL A 132
PHE A 105
LEU A 106
ALA A  78
SER A 194
 None
 1.34A 3apvA-4tx7A:
undetectable		 3apvA-4tx7A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		5 / 12 VAL A 132
PHE A 105
LEU A 106
ALA A  78
SER A 194
 None
 1.37A 3apvB-4tx7A:
undetectable		 3apvB-4tx7A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_A_DP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		5 / 12 PHE A  73
VAL A 132
PHE A 105
ALA A  78
SER A 194
 None
 1.50A 3apwA-4tx7A:
undetectable		 3apwA-4tx7A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_2
(DIHYDROFOLATE
REDUCTASE)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		4 / 4 ILE A 242
PHE A 201
ILE A 241
THR A 109
 None
 1.16A 3ia4A-4tx7A:
undetectable		 3ia4A-4tx7A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_4
(HIV-1 PROTEASE)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		3 / 3 ARG A 100
VAL A 256
THR A 239
 None
 0.74A 3k4vD-4tx7A:
undetectable		 3k4vD-4tx7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		3 / 3 ARG A 100
VAL A 256
THR A 239
 None
 0.79A 3ndtA-4tx7A:
undetectable		 3ndtA-4tx7A:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		4 / 4 SER A  48
LEU A 106
TYR A  76
PRO A  44
 None
 1.37A 4jksA-4tx7A:
undetectable		 4jksA-4tx7A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		4 / 4 SER A  48
LEU A 106
TYR A  76
PRO A  44
 None
 1.39A 4jksB-4tx7A:
undetectable		 4jksB-4tx7A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		4 / 4 SER A  48
LEU A 106
TYR A  76
PRO A  44
 None
 1.37A 4jkuA-4tx7A:
undetectable		 4jkuA-4tx7A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_2
(SUGAR KINASE)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		4 / 4 SER A  48
LEU A 106
TYR A  76
PRO A  44
 None
 1.39A 4k8cB-4tx7A:
undetectable		 4k8cB-4tx7A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_2
(SUGAR KINASE)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		4 / 4 SER A  48
LEU A 106
TYR A  76
PRO A  44
 None
 1.38A 4k8kA-4tx7A:
undetectable		 4k8kA-4tx7A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		4 / 4 SER A  48
LEU A 106
TYR A  76
PRO A  44
 None
 1.38A 4kalA-4tx7A:
undetectable		 4kalA-4tx7A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		4 / 4 SER A  48
LEU A 106
TYR A  76
PRO A  44
 None
 1.38A 4kalB-4tx7A:
undetectable		 4kalB-4tx7A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		4 / 4 SER A  48
LEU A 106
TYR A  76
PRO A  44
 None
 1.37A 4lcaA-4tx7A:
undetectable		 4lcaA-4tx7A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		4 / 4 SER A  48
LEU A 106
TYR A  76
PRO A  44
 None
 1.38A 4lcaB-4tx7A:
undetectable		 4lcaB-4tx7A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA603_1
(TRANSPORTER)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		5 / 10 ASP A 258
TYR A 266
TYR A 125
GLY A 115
GLY A 123
 None
 1.24A 4mmcA-4tx7A:
undetectable		 4mmcA-4tx7A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		4 / 7 ILE A 163
PRO A 184
ILE A 181
ASP A 179
 None
 1.01A 4w5oA-4tx7A:
undetectable		 4w5oA-4tx7A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		4 / 7 ILE A 163
PRO A 184
ILE A 181
ASP A 179
 None
 1.00A 4z4eA-4tx7A:
undetectable		 4z4eA-4tx7A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		4 / 7 ILE A 163
PRO A 184
ILE A 181
ASP A 179
 None
 1.00A 4z4gA-4tx7A:
undetectable		 4z4gA-4tx7A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 4tx7 CLASS I CHITINASE
(Vigna
unguiculata) 		4 / 8 GLY A 159
GLN A 153
VAL A 187
ASP A 185
 None
 1.03A 5vlmA-4tx7A:
undetectable		 5vlmA-4tx7A:
21.79