SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4tx8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		3 / 3 TRP A 374
ARG A 388
THR A 373
 FLC  A 505 (-3.0A)
None
None
 0.76A 1df7A-4tx8A:
undetectable		 1df7A-4tx8A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		4 / 7 SER A 263
THR A  77
VAL A  78
ALA A  81
 None
 0.86A 1fo4B-4tx8A:
undetectable		 1fo4B-4tx8A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		4 / 7 LEU A 300
LEU A 293
GLY A 295
TYR A 269
 None
 0.89A 1gtiB-4tx8A:
undetectable		 1gtiB-4tx8A:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GYX_A_BEZA1077_0
(HYPOTHETICAL PROTEIN
YDCE)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		4 / 7 PHE A 100
TRP A  89
PRO A 101
SER A 103
 None
 1.39A 1gyxA-4tx8A:
undetectable
1gyxB-4tx8A:
undetectable		 1gyxA-4tx8A:
10.33
1gyxB-4tx8A:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		5 / 12 LEU A 183
LEU A 179
ILE A 143
LEU A 195
VAL A 164
 None
 1.09A 1hrkA-4tx8A:
undetectable		 1hrkA-4tx8A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_A_ID2A1_0
(THYMIDINE KINASE)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		5 / 12 ILE A 201
ILE A 254
TYR A 251
ALA A 214
GLU A 196
 None
None
None
None
CA  A 503 (-2.2A)
 1.17A 1ki7A-4tx8A:
undetectable		 1ki7A-4tx8A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		5 / 12 GLY A 257
LEU A 228
LYS A 219
ILE A 254
LEU A 193
 None
 1.31A 1lhuA-4tx8A:
undetectable		 1lhuA-4tx8A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDT_A_VIAA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		5 / 12 ASN A 272
ILE A 255
VAL A 267
LEU A 275
MET A 299
 FLC  A 504 ( 4.1A)
None
None
None
None
 1.33A 1udtA-4tx8A:
undetectable		 1udtA-4tx8A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		5 / 11 ILE A 182
GLY A 181
THR A 184
ILE A 222
LEU A 218
 None
 0.93A 1z11A-4tx8A:
undetectable		 1z11A-4tx8A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		5 / 11 ILE A 182
GLY A 181
THR A 184
ILE A 222
LEU A 218
 None
 0.87A 1z11B-4tx8A:
undetectable		 1z11B-4tx8A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		5 / 10 ILE A 182
GLY A 181
THR A 184
ILE A 222
LEU A 218
 None
 0.91A 1z11C-4tx8A:
undetectable		 1z11C-4tx8A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		5 / 10 ILE A 182
GLY A 181
THR A 184
ILE A 222
LEU A 218
 None
 0.89A 1z11D-4tx8A:
undetectable		 1z11D-4tx8A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		5 / 9 LEU A 228
PHE A 226
LEU A 193
LEU A 157
ALA A 214
 None
 1.04A 2bxeA-4tx8A:
undetectable		 2bxeA-4tx8A:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		5 / 10 LEU A 228
PHE A 226
LEU A 193
LEU A 157
ALA A 214
 None
 0.96A 2bxeB-4tx8A:
undetectable		 2bxeB-4tx8A:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		4 / 5 ILE A 301
PHE A 314
PHE A 304
ILE A 265
 None
 1.08A 2hjhA-4tx8A:
2.4		 2hjhA-4tx8A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA701_0
(FERROCHELATASE)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		5 / 12 LEU A 183
LEU A 179
ILE A 143
LEU A 195
VAL A 164
 None
 1.11A 2hrcA-4tx8A:
undetectable		 2hrcA-4tx8A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1605_0
(FERROCHELATASE)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		5 / 12 LEU A 183
LEU A 179
ILE A 143
LEU A 195
VAL A 164
 None
 1.21A 2hrcB-4tx8A:
undetectable		 2hrcB-4tx8A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		5 / 12 LEU A 183
LEU A 179
ILE A 143
LEU A 195
VAL A 164
 None
 1.10A 2pnjA-4tx8A:
undetectable		 2pnjA-4tx8A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		5 / 12 LEU A 183
LEU A 179
ILE A 143
LEU A 195
VAL A 164
 None
 0.97A 2po5A-4tx8A:
undetectable		 2po5A-4tx8A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		5 / 12 LEU A 183
LEU A 179
ILE A 143
LEU A 195
VAL A 164
 None
 1.00A 2po7A-4tx8A:
undetectable		 2po7A-4tx8A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		5 / 12 LEU A 183
LEU A 179
ILE A 143
LEU A 195
VAL A 164
 None
 1.01A 2po7B-4tx8A:
undetectable		 2po7B-4tx8A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		6 / 9 TYR A  88
PHE A 116
ASP A 194
GLN A 268
TYR A 270
TRP A 374
 None
FLC  A 506 (-4.4A)
FLC  A 506 ( 3.0A)
FLC  A 505 ( 2.7A)
FLC  A 505 (-4.2A)
FLC  A 505 (-3.0A)
 0.43A 2uy4A-4tx8A:
23.8		 2uy4A-4tx8A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		6 / 9 TYR A  88
PHE A 116
GLY A 158
ASP A 194
GLN A 268
TYR A 270
 None
FLC  A 506 (-4.4A)
FLC  A 506 (-3.0A)
FLC  A 506 ( 3.0A)
FLC  A 505 ( 2.7A)
FLC  A 505 (-4.2A)
 0.93A 2uy4A-4tx8A:
23.8		 2uy4A-4tx8A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		5 / 9 TYR A  88
PHE A 116
GLY A 159
TYR A 270
TRP A 374
 None
FLC  A 506 (-4.4A)
FLC  A 506 (-3.3A)
FLC  A 505 (-4.2A)
FLC  A 505 (-3.0A)
 0.70A 2uy4A-4tx8A:
23.8		 2uy4A-4tx8A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		8 / 11 TYR A  88
PHE A 116
ASP A 194
GLN A 268
TYR A 270
ASN A 271
ALA A 333
TRP A 374
 None
FLC  A 506 (-4.4A)
FLC  A 506 ( 3.0A)
FLC  A 505 ( 2.7A)
FLC  A 505 (-4.2A)
FLC  A 504 ( 4.3A)
None
FLC  A 505 (-3.0A)
 0.50A 2xtkA-4tx8A:
24.5		 2xtkA-4tx8A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		6 / 11 TYR A  88
PHE A 116
GLY A 158
ASP A 194
GLN A 268
TYR A 270
 None
FLC  A 506 (-4.4A)
FLC  A 506 (-3.0A)
FLC  A 506 ( 3.0A)
FLC  A 505 ( 2.7A)
FLC  A 505 (-4.2A)
 0.96A 2xtkA-4tx8A:
24.5		 2xtkA-4tx8A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		8 / 11 TYR A  88
PHE A 116
GLY A 159
GLN A 268
TYR A 270
ASN A 271
ALA A 333
TRP A 374
 None
FLC  A 506 (-4.4A)
FLC  A 506 (-3.3A)
FLC  A 505 ( 2.7A)
FLC  A 505 (-4.2A)
FLC  A 504 ( 4.3A)
None
FLC  A 505 (-3.0A)
 0.69A 2xtkA-4tx8A:
24.5		 2xtkA-4tx8A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		6 / 10 TYR A  88
PHE A 116
ASP A 194
GLN A 268
TYR A 270
TRP A 374
 None
FLC  A 506 (-4.4A)
FLC  A 506 ( 3.0A)
FLC  A 505 ( 2.7A)
FLC  A 505 (-4.2A)
FLC  A 505 (-3.0A)
 0.44A 2xtkB-4tx8A:
24.4		 2xtkB-4tx8A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		5 / 10 TYR A  88
PHE A 116
GLY A 158
ASP A 194
GLN A 268
 None
FLC  A 506 (-4.4A)
FLC  A 506 (-3.0A)
FLC  A 506 ( 3.0A)
FLC  A 505 ( 2.7A)
 1.05A 2xtkB-4tx8A:
24.4		 2xtkB-4tx8A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		5 / 10 TYR A  88
PHE A 116
GLY A 159
TYR A 270
TRP A 374
 None
FLC  A 506 (-4.4A)
FLC  A 506 (-3.3A)
FLC  A 505 (-4.2A)
FLC  A 505 (-3.0A)
 0.81A 2xtkB-4tx8A:
24.4		 2xtkB-4tx8A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		5 / 12 LEU A  28
VAL A  29
SER A 375
SER A 332
ASN A  94
 None
 1.49A 2y00A-4tx8A:
undetectable		 2y00A-4tx8A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		3 / 3 SER A 331
ASP A 382
ASN A  21
 None
 0.70A 3lsfB-4tx8A:
undetectable
3lsfE-4tx8A:
undetectable		 3lsfB-4tx8A:
18.84
3lsfE-4tx8A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		3 / 3 ASP A 382
ASN A  21
SER A 331
 None
 0.67A 3lsfB-4tx8A:
undetectable
3lsfE-4tx8A:
undetectable		 3lsfB-4tx8A:
18.84
3lsfE-4tx8A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA802_0
(GLUTAMATE RECEPTOR 2)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		3 / 3 ASP A 382
ASN A  21
SER A 331
 None
 0.63A 3lslA-4tx8A:
undetectable
3lslD-4tx8A:
undetectable		 3lslA-4tx8A:
18.84
3lslD-4tx8A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		3 / 3 SER A 331
ASP A 382
ASN A  21
 None
 0.58A 3lslA-4tx8A:
undetectable
3lslD-4tx8A:
undetectable		 3lslA-4tx8A:
18.84
3lslD-4tx8A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		4 / 7 ASP A 192
GLY A 325
VAL A 111
VAL A 113
 None
 0.55A 3ufnB-4tx8A:
undetectable		 3ufnB-4tx8A:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		4 / 8 TYR A  88
HIS A 266
TYR A 227
LEU A 262
 None
 1.37A 3uzzB-4tx8A:
5.0		 3uzzB-4tx8A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		4 / 5 PHE A 386
LEU A 347
GLY A 370
VAL A  86
 None
 1.08A 3wrkD-4tx8A:
undetectable		 3wrkD-4tx8A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		4 / 8 LEU A 211
SER A 178
VAL A 154
GLY A 190
 None
 0.91A 4klrB-4tx8A:
undetectable		 4klrB-4tx8A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		4 / 7 ALA A 323
ILE A 301
LEU A 350
PHE A 368
 None
 1.07A 4uymA-4tx8A:
undetectable		 4uymA-4tx8A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		4 / 7 ALA A 323
ILE A 301
LEU A 350
PHE A 368
 None
 1.04A 4uymB-4tx8A:
undetectable		 4uymB-4tx8A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		4 / 8 ASN A  94
PRO A  95
PHE A  92
TRP A 374
 None
None
None
FLC  A 505 (-3.0A)
 1.44A 5amkA-4tx8A:
undetectable		 5amkA-4tx8A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		4 / 5 ILE A 254
GLY A 249
ILE A 201
LEU A 252
 None
 0.91A 5dzkd-4tx8A:
2.3
5dzkk-4tx8A:
1.2
5dzky-4tx8A:
undetectable		 5dzkd-4tx8A:
17.65
5dzkk-4tx8A:
17.31
5dzky-4tx8A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 4tx8 PROBABLE CHITINASE A
(Chromobacterium
violaceum) 		4 / 4 ILE A 254
GLY A 249
ILE A 201
LEU A 252
 None
 0.83A 5dzkl-4tx8A:
undetectable
5dzkz-4tx8A:
undetectable		 5dzkl-4tx8A:
17.31
5dzkz-4tx8A:
13.33