SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4txd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 8 CYH A 130
HIS A 154
CYH A 155
GLY A 150
 ZN  A 401 (-2.2A)
ZN  A 401 (-4.1A)
ZN  A 401 (-2.3A)
ZN  A 401 ( 4.9A)
 0.79A 1ekjA-4txdA:
undetectable
1ekjB-4txdA:
undetectable		 1ekjA-4txdA:
21.84
1ekjB-4txdA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 8 CYH A 130
HIS A 154
CYH A 155
GLY A 150
 ZN  A 401 (-2.2A)
ZN  A 401 (-4.1A)
ZN  A 401 (-2.3A)
ZN  A 401 ( 4.9A)
 0.82A 1ekjG-4txdA:
undetectable
1ekjH-4txdA:
undetectable		 1ekjG-4txdA:
21.84
1ekjH-4txdA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 4txd CSC2
(Thermofilum
pendens) 		5 / 9 THR A  85
LEU A 249
VAL A 264
ILE A 266
VAL A  39
 None
 1.00A 1gebA-4txdA:
undetectable		 1gebA-4txdA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 4txd CSC2
(Thermofilum
pendens) 		3 / 3 ARG A  87
ARG A 255
ARG A  94
 None
 1.11A 1l7fA-4txdA:
undetectable		 1l7fA-4txdA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_C_THAC3_1
(LIVER
CARBOXYLESTERASE I)		 4txd CSC2
(Thermofilum
pendens) 		5 / 12 THR A 242
LEU A 246
LEU A 252
LEU A 249
PHE A 158
 None
 1.14A 1mx1C-4txdA:
undetectable		 1mx1C-4txdA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 4txd CSC2
(Thermofilum
pendens) 		4 / 8 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 1.01A 1o76B-4txdA:
undetectable		 1o76B-4txdA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 1.02A 1t85A-4txdA:
undetectable		 1t85A-4txdA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.91A 1t85A-4txdA:
undetectable		 1t85A-4txdA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 1.01A 1t87A-4txdA:
undetectable		 1t87A-4txdA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.94A 1t87A-4txdA:
undetectable		 1t87A-4txdA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 4txd CSC2
(Thermofilum
pendens) 		4 / 8 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 1.01A 1uyuB-4txdA:
undetectable		 1uyuB-4txdA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 0.97A 1yrcA-4txdA:
undetectable		 1yrcA-4txdA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.92A 1yrcA-4txdA:
undetectable		 1yrcA-4txdA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 0.98A 1yrdA-4txdA:
undetectable		 1yrdA-4txdA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.96A 1yrdA-4txdA:
undetectable		 1yrdA-4txdA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4txd CSC2
(Thermofilum
pendens) 		4 / 8 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.84A 2a1oA-4txdA:
undetectable		 2a1oA-4txdA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 4txd CSC2
(Thermofilum
pendens) 		4 / 6 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 1.01A 2feuA-4txdA:
undetectable		 2feuA-4txdA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 4txd CSC2
(Thermofilum
pendens) 		4 / 6 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.93A 2feuA-4txdA:
undetectable		 2feuA-4txdA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 0.99A 2feuB-4txdA:
undetectable		 2feuB-4txdA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.87A 2feuB-4txdA:
undetectable		 2feuB-4txdA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 4txd CSC2
(Thermofilum
pendens) 		3 / 3 ARG A  36
ARG A 182
ARG A 228
 None
 1.15A 2jb7A-4txdA:
undetectable
2jb7B-4txdA:
2.5
2jb7C-4txdA:
2.4		 2jb7A-4txdA:
23.27
2jb7B-4txdA:
23.27
2jb7C-4txdA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 4txd CSC2
(Thermofilum
pendens) 		3 / 3 ARG A 182
ARG A 228
ARG A  36
 None
 1.17A 2jb7A-4txdA:
undetectable
2jb7B-4txdA:
2.5
2jb7C-4txdA:
2.4		 2jb7A-4txdA:
23.27
2jb7B-4txdA:
23.27
2jb7C-4txdA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JB7_B_ACTB1169_0
(HYPOTHETICAL PROTEIN
PAE2307)		 4txd CSC2
(Thermofilum
pendens) 		3 / 3 ARG A 228
ARG A  36
ARG A 182
 None
 1.17A 2jb7A-4txdA:
undetectable
2jb7B-4txdA:
2.5
2jb7C-4txdA:
2.4		 2jb7A-4txdA:
23.27
2jb7B-4txdA:
23.27
2jb7C-4txdA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 6 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 1.11A 2zuhA-4txdA:
undetectable		 2zuhA-4txdA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 6 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 1.07A 2zuhA-4txdA:
undetectable		 2zuhA-4txdA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 6 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 1.00A 2zuiA-4txdA:
undetectable		 2zuiA-4txdA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 6 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.98A 2zuiA-4txdA:
undetectable		 2zuiA-4txdA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 1.00A 2zwtA-4txdA:
undetectable		 2zwtA-4txdA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.94A 2zwtA-4txdA:
undetectable		 2zwtA-4txdA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 0.99A 2zwuA-4txdA:
undetectable		 2zwuA-4txdA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.95A 2zwuA-4txdA:
undetectable		 2zwuA-4txdA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 1.02A 3fwfA-4txdA:
undetectable		 3fwfA-4txdA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.90A 3fwfA-4txdA:
undetectable		 3fwfA-4txdA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 1.02A 3fwfB-4txdA:
undetectable		 3fwfB-4txdA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.88A 3fwfB-4txdA:
undetectable		 3fwfB-4txdA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 0.99A 3fwiA-4txdA:
undetectable		 3fwiA-4txdA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.98A 3fwiA-4txdA:
undetectable		 3fwiA-4txdA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 1.02A 3fwjA-4txdA:
undetectable		 3fwjA-4txdA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.91A 3fwjA-4txdA:
undetectable		 3fwjA-4txdA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 1.03A 3l63A-4txdA:
undetectable		 3l63A-4txdA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.88A 3l63A-4txdA:
undetectable		 3l63A-4txdA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 4txd CSC2
(Thermofilum
pendens) 		4 / 6 THR A 131
CYH A 155
GLY A 150
ASP A 149
 None
ZN  A 401 (-2.3A)
ZN  A 401 ( 4.9A)
ZN  A 401 (-2.5A)
 1.34A 3w9tE-4txdA:
undetectable		 3w9tE-4txdA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 0.99A 3wrhA-4txdA:
undetectable		 3wrhA-4txdA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.86A 3wrhA-4txdA:
undetectable		 3wrhA-4txdA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 0.99A 3wrjA-4txdA:
undetectable		 3wrjA-4txdA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.90A 3wrjA-4txdA:
undetectable		 3wrjA-4txdA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 0.99A 3wrlA-4txdA:
undetectable		 3wrlA-4txdA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.88A 3wrlA-4txdA:
undetectable		 3wrlA-4txdA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 0.99A 3wrlE-4txdA:
undetectable		 3wrlE-4txdA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.90A 3wrlE-4txdA:
undetectable		 3wrlE-4txdA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 0.99A 3wrmA-4txdA:
undetectable		 3wrmA-4txdA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.88A 3wrmA-4txdA:
undetectable		 3wrmA-4txdA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 1.01A 3wrmF-4txdA:
undetectable		 3wrmF-4txdA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.95A 3wrmF-4txdA:
undetectable		 3wrmF-4txdA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA503_0
(OXIDOREDUCTASE,
FMN-BINDING)		 4txd CSC2
(Thermofilum
pendens) 		4 / 6 SER A 335
TRP A 332
PHE A 151
PHE A 121
 None
 1.45A 4awuA-4txdA:
undetectable		 4awuA-4txdA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 8 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 1.03A 4l4bA-4txdA:
undetectable		 4l4bA-4txdA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 8 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.96A 4l4cB-4txdA:
undetectable		 4l4cB-4txdA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 8 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 1.04A 4l4dA-4txdA:
undetectable		 4l4dA-4txdA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 8 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.85A 4l4eA-4txdA:
undetectable		 4l4eA-4txdA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 8 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.88A 4l4fA-4txdA:
undetectable		 4l4fA-4txdA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 1.05A 4l4gA-4txdA:
undetectable		 4l4gA-4txdA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.86A 4l4gA-4txdA:
undetectable		 4l4gA-4txdA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 4txd CSC2
(Thermofilum
pendens) 		4 / 5 GLN A  88
THR A  85
THR A 156
LEU A 331
 None
 1.35A 4lvcA-4txdA:
undetectable		 4lvcA-4txdA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 4txd CSC2
(Thermofilum
pendens) 		4 / 5 GLN A  88
THR A  85
THR A 156
LEU A 331
 None
 1.36A 4lvcC-4txdA:
undetectable		 4lvcC-4txdA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)		 4txd CSC2
(Thermofilum
pendens) 		4 / 6 LEU A 234
MET A  89
LEU A 331
ILE A  24
 None
 1.00A 4okxA-4txdA:
undetectable		 4okxA-4txdA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5INZ_D_DVAD15_0
(THETA DEFENSIN-2,
D-PEPTIDE
THETA DEFENSIN-2,
L-PEPTIDE)		 4txd CSC2
(Thermofilum
pendens) 		3 / 3 GLY A 150
CYH A 155
CYH A 152
 ZN  A 401 ( 4.9A)
ZN  A 401 (-2.3A)
ZN  A 401 (-2.2A)
 0.94A 5inzB-4txdA:
undetectable		 5inzB-4txdA:
6.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 4txd CSC2
(Thermofilum
pendens) 		5 / 11 ALA A 283
THR A 189
ALA A 188
GLY A 227
ALA A 279
 None
 1.01A 5lf3K-4txdA:
undetectable
5lf3L-4txdA:
undetectable		 5lf3K-4txdA:
22.53
5lf3L-4txdA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 4txd CSC2
(Thermofilum
pendens) 		5 / 11 ALA A 283
THR A 189
ALA A 188
GLY A 227
ALA A 279
 None
 1.00A 5lf3Y-4txdA:
undetectable
5lf3Z-4txdA:
undetectable		 5lf3Y-4txdA:
22.53
5lf3Z-4txdA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 4 GLN A  88
THR A  85
THR A 156
LEU A 331
 None
 1.42A 5m5kA-4txdA:
undetectable		 5m5kA-4txdA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 4 GLN A  88
THR A  85
THR A 156
LEU A 331
 None
 1.43A 5m5kC-4txdA:
undetectable		 5m5kC-4txdA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A  43
VAL A  39
 None
 1.05A 5wk9A-4txdA:
undetectable		 5wk9A-4txdA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4txd CSC2
(Thermofilum
pendens) 		4 / 7 THR A  85
LEU A 249
VAL A 264
VAL A  39
 None
 0.79A 5wk9A-4txdA:
undetectable		 5wk9A-4txdA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11802_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
UL4
RIBOSOMAL PROTEIN
UL15
RIBOSOMAL PROTEIN
EL15)		 4txd CSC2
(Thermofilum
pendens) 		3 / 3 ARG A  29
LYS A 115
ARG A  22
 None
 1.31A 6az3C-4txdA:
undetectable
6az3L-4txdA:
undetectable
6az3M-4txdA:
undetectable		 6az3C-4txdA:
11.57
6az3L-4txdA:
10.05
6az3M-4txdA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA820_0
(GEPHYRIN)		 4txd CSC2
(Thermofilum
pendens) 		4 / 5 GLU A 238
PRO A 153
THR A 156
MET A  89
 None
 1.49A 6fgdA-4txdA:
undetectable		 6fgdA-4txdA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 4txd CSC2
(Thermofilum
pendens) 		4 / 5 GLN A  88
THR A  85
THR A 156
LEU A 331
 None
 1.36A 6gbnA-4txdA:
undetectable		 6gbnA-4txdA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 4txd CSC2
(Thermofilum
pendens) 		4 / 5 GLN A  88
THR A  85
THR A 156
LEU A 331
 None
 1.36A 6gbnD-4txdA:
undetectable		 6gbnD-4txdA:
21.71