SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4txg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 4txg CHITINASE
(Chromobacterium
violaceum) 		6 / 9 TYR A 159
PHE A 190
GLY A 254
ASP A 312
ASP A 398
TRP A 603
 None
None
None
None
CS  A 812 (-4.0A)
CS  A 812 ( 4.2A)
 0.96A 1e9lA-4txgA:
34.4		 1e9lA-4txgA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 4txg CHITINASE
(Chromobacterium
violaceum) 		7 / 9 TYR A 159
PHE A 190
GLY A 254
ASP A 312
MET A 395
TYR A 397
ASP A 398
 None
None
None
None
CS  A 803 (-3.5A)
CS  A 812 (-4.4A)
CS  A 812 (-4.0A)
 0.68A 1e9lA-4txgA:
34.4		 1e9lA-4txgA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_CCSA381_0
(ESTROGEN RECEPTOR)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 5 HIS A 192
GLU A 257
ALA A 189
SER A 251
 None
 1.36A 1errA-4txgA:
undetectable
1errB-4txgA:
undetectable		 1errA-4txgA:
15.19
1errB-4txgA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 9 GLY A 283
ARG A 334
ALA A 333
LEU A 335
GLY A 336
 None
 1.39A 1jb0A-4txgA:
undetectable		 1jb0A-4txgA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_A_DOLA300_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 11 PRO A 453
LEU A 452
VAL A 134
TYR A 363
ASP A 354
 None
 1.28A 1mrlA-4txgA:
undetectable
1mrlB-4txgA:
undetectable		 1mrlA-4txgA:
13.51
1mrlB-4txgA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_B_DOLB301_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 12 PRO A 453
LEU A 452
VAL A 134
TYR A 363
ASP A 354
 None
 1.29A 1mrlB-4txgA:
undetectable
1mrlC-4txgA:
undetectable		 1mrlB-4txgA:
13.51
1mrlC-4txgA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 12 ILE A 250
PHE A 274
VAL A 309
ILE A 311
ILE A 290
 None
 1.20A 1r5lA-4txgA:
1.2		 1r5lA-4txgA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 7 ARG A 449
LEU A 377
GLY A 374
TYR A 315
 None
 0.75A 1rtsB-4txgA:
undetectable		 1rtsB-4txgA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 11 GLY A 451
GLY A 450
GLU A 783
SER A 767
HIS A 768
 None
 1.29A 1w76A-4txgA:
undetectable		 1w76A-4txgA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		9 / 11 TYR A 159
PHE A 190
GLY A 254
ASP A 312
MET A 395
TYR A 397
ASP A 398
TYR A 464
TRP A 603
 None
None
None
None
CS  A 803 (-3.5A)
CS  A 812 (-4.4A)
CS  A 812 (-4.0A)
CS  A 812 (-4.5A)
CS  A 812 ( 4.2A)
 0.78A 2a3aA-4txgA:
34.8		 2a3aA-4txgA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		10 / 11 TYR A 159
PHE A 190
GLY A 254
TRP A 255
GLU A 314
MET A 395
TYR A 397
ASP A 398
TYR A 464
TRP A 603
 None
None
None
None
CS  A 803 (-2.9A)
CS  A 803 (-3.5A)
CS  A 812 (-4.4A)
CS  A 812 (-4.0A)
CS  A 812 (-4.5A)
CS  A 812 ( 4.2A)
 0.62A 2a3aA-4txgA:
34.8		 2a3aA-4txgA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		3 / 3 TRP A 255
GLU A 314
TYR A 315
 None
CS  A 803 (-2.9A)
None
 0.34A 2a3aA-4txgA:
34.8		 2a3aA-4txgA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		8 / 9 PHE A 190
GLY A 254
GLU A 314
MET A 395
TYR A 397
ASP A 398
TYR A 464
TRP A 603
 None
None
CS  A 803 (-2.9A)
CS  A 803 (-3.5A)
CS  A 812 (-4.4A)
CS  A 812 (-4.0A)
CS  A 812 (-4.5A)
CS  A 812 ( 4.2A)
 0.47A 2a3aB-4txgA:
34.9		 2a3aB-4txgA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		8 / 11 TYR A 159
PHE A 190
GLY A 254
ASP A 312
GLU A 314
MET A 395
TYR A 397
TRP A 603
 None
None
None
None
CS  A 803 (-2.9A)
CS  A 803 (-3.5A)
CS  A 812 (-4.4A)
CS  A 812 ( 4.2A)
 0.99A 2a3bA-4txgA:
34.8		 2a3bA-4txgA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		9 / 11 TYR A 159
PHE A 190
GLY A 254
ASP A 312
MET A 395
TYR A 397
ASP A 398
TYR A 464
TRP A 603
 None
None
None
None
CS  A 803 (-3.5A)
CS  A 812 (-4.4A)
CS  A 812 (-4.0A)
CS  A 812 (-4.5A)
CS  A 812 ( 4.2A)
 0.83A 2a3bA-4txgA:
34.8		 2a3bA-4txgA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		8 / 10 PHE A 190
GLY A 254
ASP A 312
GLU A 314
MET A 395
TYR A 397
ASP A 398
TRP A 603
 None
None
None
CS  A 803 (-2.9A)
CS  A 803 (-3.5A)
CS  A 812 (-4.4A)
CS  A 812 (-4.0A)
CS  A 812 ( 4.2A)
 0.95A 2a3bB-4txgA:
34.9		 2a3bB-4txgA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		8 / 10 PHE A 190
GLY A 254
ASP A 312
MET A 395
TYR A 397
ASP A 398
TYR A 464
TRP A 603
 None
None
None
CS  A 803 (-3.5A)
CS  A 812 (-4.4A)
CS  A 812 (-4.0A)
CS  A 812 (-4.5A)
CS  A 812 ( 4.2A)
 0.79A 2a3bB-4txgA:
34.9		 2a3bB-4txgA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		10 / 12 TYR A 159
TRP A 163
PHE A 190
GLY A 254
ASP A 312
GLU A 314
MET A 395
TYR A 397
ASP A 398
TRP A 603
 None
None
None
None
None
CS  A 803 (-2.9A)
CS  A 803 (-3.5A)
CS  A 812 (-4.4A)
CS  A 812 (-4.0A)
CS  A 812 ( 4.2A)
 0.93A 2a3cA-4txgA:
34.8		 2a3cA-4txgA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		10 / 12 TYR A 159
TRP A 163
PHE A 190
GLY A 254
ASP A 312
MET A 395
TYR A 397
ASP A 398
TYR A 464
TRP A 603
 None
None
None
None
None
CS  A 803 (-3.5A)
CS  A 812 (-4.4A)
CS  A 812 (-4.0A)
CS  A 812 (-4.5A)
CS  A 812 ( 4.2A)
 0.79A 2a3cA-4txgA:
34.8		 2a3cA-4txgA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		9 / 12 TRP A 163
PHE A 190
GLY A 254
ASP A 312
GLU A 314
MET A 395
TYR A 397
ASP A 398
TRP A 603
 None
None
None
None
CS  A 803 (-2.9A)
CS  A 803 (-3.5A)
CS  A 812 (-4.4A)
CS  A 812 (-4.0A)
CS  A 812 ( 4.2A)
 0.91A 2a3cB-4txgA:
34.8		 2a3cB-4txgA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		9 / 12 TRP A 163
PHE A 190
GLY A 254
ASP A 312
MET A 395
TYR A 397
ASP A 398
TYR A 464
TRP A 603
 None
None
None
None
CS  A 803 (-3.5A)
CS  A 812 (-4.4A)
CS  A 812 (-4.0A)
CS  A 812 (-4.5A)
CS  A 812 ( 4.2A)
 0.77A 2a3cB-4txgA:
34.8		 2a3cB-4txgA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 7 ALA A 444
TYR A 448
TYR A 397
TYR A 159
 None
None
CS  A 812 (-4.4A)
None
 1.17A 2ajvH-4txgA:
2.1
2ajvL-4txgA:
2.3		 2ajvH-4txgA:
14.16
2ajvL-4txgA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4txg CHITINASE
(Chromobacterium
violaceum) 		3 / 3 LYS A 573
ASP A 507
ASP A 502
 None
 0.87A 2br4D-4txgA:
undetectable		 2br4D-4txgA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_A_SAMA1217_0
(CATECHOL
O-METHYLTRANSFERASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 12 VAL A 394
GLY A 599
TYR A 448
ASN A 596
SER A 152
 None
 1.48A 2cl5A-4txgA:
0.9		 2cl5A-4txgA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		7 / 9 TYR A 159
PHE A 190
GLY A 254
ASP A 312
GLU A 314
TYR A 397
TRP A 603
 None
None
None
None
CS  A 803 (-2.9A)
CS  A 812 (-4.4A)
CS  A 812 ( 4.2A)
 0.54A 2uy4A-4txgA:
16.7		 2uy4A-4txgA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_A_PFNA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 5 TYR A 342
PHE A 383
VAL A 392
TYR A 315
 None
 1.37A 2x7hA-4txgA:
undetectable		 2x7hA-4txgA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_B_PFNB1372_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 5 TYR A 342
PHE A 383
VAL A 392
TYR A 315
 None
 1.37A 2x7hB-4txgA:
undetectable		 2x7hB-4txgA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 4txg CHITINASE
(Chromobacterium
violaceum) 		7 / 11 TYR A 159
PHE A 190
GLY A 254
ASP A 312
GLU A 314
TYR A 397
TRP A 603
 None
None
None
None
CS  A 803 (-2.9A)
CS  A 812 (-4.4A)
CS  A 812 ( 4.2A)
 0.86A 2xtkA-4txgA:
17.7		 2xtkA-4txgA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 4txg CHITINASE
(Chromobacterium
violaceum) 		7 / 10 TYR A 159
PHE A 190
GLY A 254
ASP A 312
GLU A 314
TYR A 397
TRP A 603
 None
None
None
None
CS  A 803 (-2.9A)
CS  A 812 (-4.4A)
CS  A 812 ( 4.2A)
 0.70A 2xtkB-4txgA:
17.8		 2xtkB-4txgA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 12 LEU A 301
THR A 367
ASP A 390
SER A 455
TYR A 363
 None
 1.50A 2y00B-4txgA:
undetectable		 2y00B-4txgA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 7 TRP A 255
ASP A 398
TRP A 403
ARG A 466
 None
CS  A 812 (-4.0A)
None
None
 0.95A 3arrA-4txgA:
30.6		 3arrA-4txgA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 6 PRO A 488
GLY A 484
GLY A 497
GLY A 495
GLY A 517
 None
 1.20A 3bogA-4txgA:
undetectable
3bogC-4txgA:
undetectable		 3bogA-4txgA:
undetectable
3bogC-4txgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 12 ILE A 585
ALA A 586
GLN A 587
ALA A 564
ILE A 156
 None
 1.06A 3e00A-4txgA:
undetectable		 3e00A-4txgA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 7 GLY A 660
ASP A 658
ILE A 657
VAL A 771
 None
 0.81A 3fi0E-4txgA:
undetectable		 3fi0E-4txgA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 8 GLY A 660
ASP A 658
ILE A 657
VAL A 771
 None
 0.77A 3fi0G-4txgA:
undetectable		 3fi0G-4txgA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 8 GLY A 660
ASP A 658
ILE A 657
VAL A 771
 None
 0.78A 3fi0Q-4txgA:
undetectable		 3fi0Q-4txgA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		6 / 11 PHE A 190
GLY A 254
TRP A 255
GLU A 314
TYR A 464
TRP A 603
 None
None
None
CS  A 803 (-2.9A)
CS  A 812 (-4.5A)
CS  A 812 ( 4.2A)
 0.78A 3g6mA-4txgA:
34.4		 3g6mA-4txgA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		7 / 11 TYR A 159
PHE A 190
GLY A 254
ASP A 312
TYR A 397
TYR A 464
TRP A 603
 None
None
None
None
CS  A 812 (-4.4A)
CS  A 812 (-4.5A)
CS  A 812 ( 4.2A)
 0.90A 3g6mA-4txgA:
34.4		 3g6mA-4txgA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		9 / 11 TYR A 159
PHE A 190
GLY A 254
GLU A 314
MET A 395
TYR A 397
ASP A 398
TYR A 464
TRP A 603
 None
None
None
CS  A 803 (-2.9A)
CS  A 803 (-3.5A)
CS  A 812 (-4.4A)
CS  A 812 (-4.0A)
CS  A 812 (-4.5A)
CS  A 812 ( 4.2A)
 0.52A 3g6mA-4txgA:
34.4		 3g6mA-4txgA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA427_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 5 TYR A 315
MET A 395
ASP A 398
TRP A 403
 None
CS  A 803 (-3.5A)
CS  A 812 (-4.0A)
None
 0.56A 3g6mA-4txgA:
34.4		 3g6mA-4txgA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 11 LEU A 301
PHE A 300
ILE A 250
PHE A 313
PHE A 293
 None
 1.49A 3ko0O-4txgA:
undetectable
3ko0P-4txgA:
undetectable
3ko0Q-4txgA:
undetectable
3ko0R-4txgA:
undetectable		 3ko0O-4txgA:
8.32
3ko0P-4txgA:
8.32
3ko0Q-4txgA:
8.32
3ko0R-4txgA:
8.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 4txg CHITINASE
(Chromobacterium
violaceum) 		3 / 3 SER A 481
SER A 482
HIS A 400
 None
 0.76A 3mzeA-4txgA:
undetectable		 3mzeA-4txgA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_A_PQNA847_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 9 GLY A 283
ARG A 334
ALA A 333
LEU A 335
GLY A 336
 None
 1.40A 3pcqA-4txgA:
undetectable		 3pcqA-4txgA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_1
(MNMC2)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 6 GLY A 467
ASP A 419
ASN A 404
GLU A 421
 None
 1.00A 3vywC-4txgA:
undetectable		 3vywC-4txgA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		11 / 11 PHE A 190
GLY A 254
TRP A 255
ASP A 312
GLU A 314
MET A 395
TYR A 397
ASP A 398
TYR A 464
ARG A 466
TRP A 603
 None
None
None
None
CS  A 803 (-2.9A)
CS  A 803 (-3.5A)
CS  A 812 (-4.4A)
CS  A 812 (-4.0A)
CS  A 812 (-4.5A)
None
CS  A 812 ( 4.2A)
 0.46A 3wqvA-4txgA:
34.7		 3wqvA-4txgA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA502_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 4 TRP A 163
GLY A 254
TRP A 255
ALA A 256
 None
 0.54A 3wqvA-4txgA:
34.7		 3wqvA-4txgA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		11 / 11 PHE A 190
GLY A 254
TRP A 255
ASP A 312
GLU A 314
MET A 395
TYR A 397
ASP A 398
TYR A 464
ARG A 466
TRP A 603
 None
None
None
None
CS  A 803 (-2.9A)
CS  A 803 (-3.5A)
CS  A 812 (-4.4A)
CS  A 812 (-4.0A)
CS  A 812 (-4.5A)
None
CS  A 812 ( 4.2A)
 0.48A 3wqwA-4txgA:
34.7		 3wqwA-4txgA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 5 TRP A 163
GLY A 254
TRP A 255
ALA A 256
 None
 0.54A 3wqwA-4txgA:
34.7		 3wqwA-4txgA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD391_1
(TETX2 PROTEIN)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 11 PHE A 576
ASN A 570
GLY A 477
GLY A 518
ASN A 410
 None
 1.24A 4a99D-4txgA:
undetectable		 4a99D-4txgA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 7 ASP A 224
GLY A 231
THR A 211
SER A 226
 None
 1.05A 4ac9C-4txgA:
2.7		 4ac9C-4txgA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_1
(WBDD)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 6 TYR A 363
GLN A 365
ARG A 350
GLN A 147
 None
 1.14A 4azvA-4txgA:
undetectable		 4azvA-4txgA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 4 LEU A 689
PRO A 690
LEU A 773
ILE A 657
 None
 0.95A 4f4dB-4txgA:
undetectable		 4f4dB-4txgA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_A_LYAA302_1
(THYMIDYLATE SYNTHASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 12 GLU A 783
LEU A 452
GLY A 451
TYR A 445
ALA A 454
 None
 1.21A 4fqsA-4txgA:
undetectable		 4fqsA-4txgA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_B_LYAB302_1
(THYMIDYLATE SYNTHASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 12 GLU A 783
LEU A 452
GLY A 451
TYR A 445
ALA A 454
 None
 1.22A 4fqsB-4txgA:
undetectable		 4fqsB-4txgA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 5 LEU A 689
PRO A 690
LEU A 773
ILE A 657
 None
 0.81A 4klrA-4txgA:
undetectable		 4klrA-4txgA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 9 MET A 380
PHE A 383
LEU A 346
GLY A 385
ALA A 189
 None
 1.40A 4l6va-4txgA:
undetectable
4l6vf-4txgA:
undetectable		 4l6va-4txgA:
20.56
4l6vf-4txgA:
9.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 12 GLY A 518
GLY A 517
GLY A 401
ALA A 402
SER A 396
 None
 0.96A 4rtmA-4txgA:
undetectable		 4rtmA-4txgA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 12 ASP A 581
SER A 584
THR A 635
ALA A 589
TYR A 609
 None
 1.50A 4u15A-4txgA:
undetectable		 4u15A-4txgA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 12 LYS A 303
LEU A 301
THR A 248
VAL A 252
ALA A 191
 None
 1.10A 4x1iB-4txgA:
2.8		 4x1iB-4txgA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 4 PHE A 190
ASP A 310
GLY A 254
SER A 251
 None
 1.33A 4xp9C-4txgA:
undetectable		 4xp9C-4txgA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		3 / 3 ARG A 736
ASP A 698
TYR A 769
 None
 0.94A 4yo9B-4txgA:
undetectable		 4yo9B-4txgA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 4txg CHITINASE
(Chromobacterium
violaceum) 		3 / 3 ARG A 155
TYR A 140
GLU A 146
 None
 0.65A 4zzbE-4txgA:
undetectable		 4zzbE-4txgA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		3 / 3 TRP A 255
GLU A 314
ASP A 398
 None
CS  A 803 (-2.9A)
CS  A 812 (-4.0A)
 0.50A 5gqbA-4txgA:
32.5		 5gqbA-4txgA:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		8 / 8 PHE A 190
GLY A 254
TRP A 255
GLU A 314
TYR A 397
ASP A 398
ARG A 466
TRP A 603
 None
None
None
CS  A 803 (-2.9A)
CS  A 812 (-4.4A)
CS  A 812 (-4.0A)
None
CS  A 812 ( 4.2A)
 0.60A 5gqbA-4txgA:
32.5		 5gqbA-4txgA:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 6 ILE A 592
VAL A 461
VAL A 600
SER A 396
 None
 0.92A 5jwaH-4txgA:
undetectable		 5jwaH-4txgA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 9 GLY A 283
ARG A 334
ALA A 333
LEU A 335
GLY A 336
 None
 1.38A 5l8rA-4txgA:
undetectable		 5l8rA-4txgA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N9X_A_THRA601_0
(ADENYLATION DOMAIN)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 7 ASP A 327
PHE A 330
GLY A 273
GLY A 260
 None
 0.99A 5n9xA-4txgA:
undetectable		 5n9xA-4txgA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 7 ASP A 416
HIS A 400
ASP A 419
ASN A 440
 None
 0.99A 5nnwD-4txgA:
undetectable		 5nnwD-4txgA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 7 GLY A 437
ASP A 416
HIS A 400
ASP A 419
 None
 0.86A 5nnwD-4txgA:
undetectable		 5nnwD-4txgA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 7 ASP A 416
HIS A 400
ASP A 419
ASN A 440
 None
 0.99A 5no9D-4txgA:
undetectable		 5no9D-4txgA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 7 GLY A 437
ASP A 416
HIS A 400
ASP A 419
 None
 0.91A 5no9D-4txgA:
undetectable		 5no9D-4txgA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		3 / 3 GLY A 732
LEU A 730
HIS A 722
 None
 0.63A 5u63A-4txgA:
undetectable		 5u63A-4txgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		3 / 3 GLY A 732
LEU A 730
HIS A 722
 None
 0.65A 5u63B-4txgA:
undetectable		 5u63B-4txgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_B_SALB503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 7 THR A 184
HIS A 185
PHE A 391
GLN A 365
 None
 1.48A 5u6mB-4txgA:
2.9		 5u6mB-4txgA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 4 LEU A 628
LEU A 631
SER A 584
ALA A 586
 None
 0.99A 5uunA-4txgA:
undetectable		 5uunA-4txgA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 8 GLY A 561
TRP A 567
ARG A 557
GLN A 556
 None
 1.05A 5vlmA-4txgA:
undetectable		 5vlmA-4txgA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWP_A_FVXA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 9 ASN A 187
SER A 251
PHE A 300
GLY A 305
THR A 211
 None
 1.41A 6awpA-4txgA:
undetectable		 6awpA-4txgA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 7 HIS A 524
ASN A 527
GLU A 621
ARG A 615
 None
 1.13A 6b8kA-4txgA:
undetectable		 6b8kA-4txgA:
7.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 12 PHE A 330
GLY A 289
THR A 258
GLY A 259
GLY A 260
 None
 0.93A 6brdB-4txgA:
undetectable		 6brdB-4txgA:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CGD_A_AKNA600_1
(BIFUNCTIONAL AAC/APH)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 10 GLY A 460
TYR A 397
ASP A 310
GLU A 257
GLU A 314
 None
CS  A 812 (-4.4A)
None
None
CS  A 803 (-2.9A)
 1.41A 6cgdA-4txgA:
undetectable		 6cgdA-4txgA:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 4txg CHITINASE
(Chromobacterium
violaceum) 		5 / 11 THR A 635
PHE A 636
THR A 441
LEU A 413
ALA A 411
 None
 1.43A 6efnA-4txgA:
3.6		 6efnA-4txgA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 4txg CHITINASE
(Chromobacterium
violaceum) 		3 / 3 ASP A 168
ASP A 507
ASN A 324
 None
 0.70A 6gngB-4txgA:
undetectable		 6gngB-4txgA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4txg CHITINASE
(Chromobacterium
violaceum) 		4 / 7 ASP A 733
ARG A 449
TYR A 445
GLU A 124
 None
 1.17A 6mn5E-4txgA:
undetectable		 6mn5E-4txgA:
8.24