SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4txk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_A_ZMRA466_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.21A 1a4gA-4txkA:
undetectable		 1a4gA-4txkA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.14A 1a4gB-4txkA:
undetectable		 1a4gB-4txkA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.12A 1nncA-4txkA:
undetectable		 1nncA-4txkA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 11 GLN A 441
LEU A 442
LEU A 469
ASN A 470
LEU A 439
 None
 1.01A 2ceoA-4txkA:
undetectable		 2ceoA-4txkA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.13A 2cmlA-4txkA:
undetectable		 2cmlA-4txkA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2477_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.14A 2cmlB-4txkA:
undetectable		 2cmlB-4txkA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3477_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.13A 2cmlC-4txkA:
undetectable		 2cmlC-4txkA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4477_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.17A 2cmlD-4txkA:
undetectable		 2cmlD-4txkA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		4 / 8 VAL A 101
VAL A 167
LEU A 105
TYR A  48
 None
 0.97A 2ddwA-4txkA:
undetectable		 2ddwA-4txkA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		4 / 7 VAL A 261
LEU A 273
PHE A 294
THR A 342
 None
 1.09A 2f78B-4txkA:
undetectable		 2f78B-4txkA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HTQ_A_ZMRA472_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.23A 2htqA-4txkA:
undetectable		 2htqA-4txkA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA426_0
(FERROCHELATASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		4 / 4 LEU A 430
PRO A 429
LEU A 433
ARG A 377
 None
 1.40A 2qd2A-4txkA:
undetectable		 2qd2A-4txkA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 10 GLN A 441
LEU A 442
LEU A 469
ASN A 470
LEU A 439
 None
 0.98A 2riwA-4txkA:
0.1
2riwB-4txkA:
undetectable		 2riwA-4txkA:
19.77
2riwB-4txkA:
5.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		4 / 8 LEU A 443
ARG A 408
GLY A 409
ALA A 412
 None
 0.89A 2xfsA-4txkA:
undetectable		 2xfsA-4txkA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		4 / 8 LEU A 443
ARG A 408
GLY A 409
ALA A 412
 None
 0.89A 2xh9A-4txkA:
undetectable		 2xh9A-4txkA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN6_A_T44A1370_1
(THYROXINE-BINDING
GLOBULIN)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 10 GLN A 441
LEU A 442
LEU A 469
ASN A 470
LEU A 439
 None
 1.06A 2xn6A-4txkA:
0.3
2xn6B-4txkA:
undetectable		 2xn6A-4txkA:
21.04
2xn6B-4txkA:
5.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN7_A_T44A1355_1
(THYROXINE-BINDING
GLOBULIN)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 10 GLN A 441
LEU A 442
LEU A 469
ASN A 470
LEU A 439
 None
 1.04A 2xn7A-4txkA:
undetectable
2xn7B-4txkA:
undetectable		 2xn7A-4txkA:
21.21
2xn7B-4txkA:
5.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 LEU A 103
LEU A 106
ALA A 424
LEU A 387
ASP A 212
 None
 1.25A 3gwuA-4txkA:
undetectable		 3gwuA-4txkA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ALA A 363
LEU A 303
LEU A 319
GLN A 318
ARG A 233
 None
 1.11A 3ix9A-4txkA:
undetectable		 3ix9A-4txkA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 9 LEU A 160
VAL A 101
LEU A 460
PHE A 410
VAL A 406
 None
 1.33A 3jwqA-4txkA:
undetectable		 3jwqA-4txkA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_0
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.23A 3k37B-4txkA:
undetectable		 3k37B-4txkA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_B_DXCB92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		4 / 5 VAL A 326
VAL A 325
ARG A 310
LYS A 300
 None
 1.49A 3rv5A-4txkA:
undetectable
3rv5B-4txkA:
undetectable		 3rv5A-4txkA:
11.80
3rv5B-4txkA:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_A_ZMRA901_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.19A 3sanA-4txkA:
undetectable		 3sanA-4txkA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_B_ZMRB901_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.19A 3sanB-4txkA:
undetectable		 3sanB-4txkA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.14A 3ticA-4txkA:
undetectable		 3ticA-4txkA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_B_ZMRB1002_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.17A 3ticB-4txkA:
undetectable		 3ticB-4txkA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_C_ZMRC1002_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.15A 3ticC-4txkA:
undetectable		 3ticC-4txkA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_D_ZMRD1002_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.17A 3ticD-4txkA:
undetectable		 3ticD-4txkA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		4 / 5 ARG A  98
LEU A 164
VAL A 167
ASP A 134
 None
 0.82A 3ufnA-4txkA:
undetectable
3ufnB-4txkA:
undetectable		 3ufnA-4txkA:
9.67
3ufnB-4txkA:
9.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		4 / 8 PHE A 351
VAL A 361
MET A 296
ILE A 240
 None
 0.98A 4a97D-4txkA:
undetectable		 4a97D-4txkA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_A_ZMRA700_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.22A 4cpnA-4txkA:
undetectable		 4cpnA-4txkA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_B_ZMRB700_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.14A 4cpnB-4txkA:
undetectable		 4cpnB-4txkA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.19A 4cpzA-4txkA:
undetectable		 4cpzA-4txkA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.15A 4cpzB-4txkA:
undetectable		 4cpzB-4txkA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.19A 4cpzC-4txkA:
undetectable		 4cpzC-4txkA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.14A 4cpzD-4txkA:
undetectable		 4cpzD-4txkA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.14A 4cpzE-4txkA:
undetectable		 4cpzE-4txkA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.19A 4cpzF-4txkA:
undetectable		 4cpzF-4txkA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.18A 4cpzG-4txkA:
undetectable		 4cpzG-4txkA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.15A 4cpzH-4txkA:
undetectable		 4cpzH-4txkA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.14A 4i00A-4txkA:
undetectable		 4i00A-4txkA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 CYH A 394
ALA A 413
GLY A 389
ALA A 416
TYR A 440
 None
 1.15A 4lg1C-4txkA:
undetectable		 4lg1C-4txkA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.13A 4mwrA-4txkA:
undetectable		 4mwrA-4txkA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.12A 4mwxA-4txkA:
undetectable		 4mwxA-4txkA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		3 / 3 ASP A 134
LYS A  66
LEU A  63
 None
 1.04A 4ptjA-4txkA:
undetectable		 4ptjA-4txkA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WA5_A_ZMRA501_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.18A 4wa5A-4txkA:
undetectable		 4wa5A-4txkA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 LEU A  97
ALA A  92
VAL A 173
LYS A 166
ALA A 168
 None
 1.14A 4x1iB-4txkA:
2.9		 4x1iB-4txkA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 LEU A  97
VAL A 173
VAL A  89
TRP A 177
LEU A 165
 None
 1.49A 5cymA-4txkA:
undetectable		 5cymA-4txkA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		4 / 8 GLU A 102
LEU A 460
ARG A  70
LEU A 439
 None
 1.22A 5dxeA-4txkA:
undetectable		 5dxeA-4txkA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G44_A_YTZA1512_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 9 LEU A 106
VAL A 432
ARG A 422
MET A 419
ALA A 417
 None
 1.48A 5g44A-4txkA:
undetectable		 5g44A-4txkA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L17_A_ZMRA512_1
(NEURAMINIDASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ARG A 230
GLU A 373
ALA A 473
GLU A 437
ARG A 371
 None
 1.13A 5l17A-4txkA:
undetectable		 5l17A-4txkA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 ALA A 363
LEU A 330
ARG A 358
GLY A 307
ILE A 238
 None
 1.12A 5m24A-4txkA:
undetectable		 5m24A-4txkA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_2
(PROTEIN CYP51)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		4 / 7 VAL A 546
PRO A 596
LEU A 597
PHE A 532
 None
 1.14A 6aycA-4txkA:
undetectable		 6aycA-4txkA:
7.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 LEU A  97
VAL A 173
VAL A  89
TRP A 177
LEU A 165
 None
 1.47A 6eliA-4txkA:
2.3		 6eliA-4txkA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		4 / 5 ARG A 136
ALA A 140
TYR A 144
ILE A 155
 None
 1.32A 6g9bA-4txkA:
undetectable
6g9bB-4txkA:
undetectable		 6g9bA-4txkA:
9.03
6g9bB-4txkA:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_1
(-)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 VAL A 391
ASP A 289
ARG A 121
GLU A 114
GLY A  91
 None
None
FAD  A 702 (-2.8A)
FAD  A 702 (-2.7A)
FAD  A 702 (-3.3A)
 1.49A 6gnfA-4txkA:
3.6		 6gnfA-4txkA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)		 4txk PROTEIN-METHIONINE
SULFOXIDE OXIDASE
MICAL1
(Mus
musculus) 		5 / 12 VAL A 391
ASP A 289
ARG A 121
GLU A 114
GLY A  91
 None
None
FAD  A 702 (-2.8A)
FAD  A 702 (-2.7A)
FAD  A 702 (-3.3A)
 1.47A 6gnfC-4txkA:
2.2		 6gnfC-4txkA:
23.53