SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4tym'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_A_ADNA1260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 10 ARG A 109
THR A 112
GLU A 201
MET A 202
GLU A 203
 SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
SO4  A 301 ( 4.4A)
 0.51A 1jdvA-4tymA:
33.9
1jdvD-4tymA:
21.8		 1jdvA-4tymA:
30.38
1jdvD-4tymA:
30.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_A_ADNA1260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 10 ARG A 109
THR A 112
MET A 202
GLU A 203
ASP A 226
 SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
SO4  A 301 ( 4.4A)
None
 0.85A 1jdvA-4tymA:
33.9
1jdvD-4tymA:
21.8		 1jdvA-4tymA:
30.38
1jdvD-4tymA:
30.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_B_ADNB2260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 10 ARG A 109
THR A 112
GLU A 201
MET A 202
GLU A 203
 SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
SO4  A 301 ( 4.4A)
 0.51A 1jdvB-4tymA:
21.6
1jdvC-4tymA:
35.2		 1jdvB-4tymA:
30.38
1jdvC-4tymA:
30.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_B_ADNB2260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 10 ARG A 109
THR A 112
MET A 202
GLU A 203
ASP A 226
 SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
SO4  A 301 ( 4.4A)
None
 0.85A 1jdvB-4tymA:
21.6
1jdvC-4tymA:
35.2		 1jdvB-4tymA:
30.38
1jdvC-4tymA:
30.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_D_ADND3260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 10 ARG A 109
THR A 112
GLU A 201
MET A 202
GLU A 203
 SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
SO4  A 301 ( 4.4A)
 0.51A 1jdvA-4tymA:
33.9
1jdvD-4tymA:
21.8		 1jdvA-4tymA:
30.38
1jdvD-4tymA:
30.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		7 / 12 ARG A 109
THR A 112
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
 SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
None
SO4  A 301 ( 4.4A)
None
 0.48A 1jdvE-4tymA:
33.9
1jdvF-4tymA:
35.3		 1jdvE-4tymA:
30.38
1jdvF-4tymA:
30.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 12 ARG A 109
THR A 112
MET A 202
GLU A 203
SER A 225
ASP A 226
 SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
SO4  A 301 ( 4.4A)
None
None
 0.81A 1jdvE-4tymA:
33.9
1jdvF-4tymA:
35.3		 1jdvE-4tymA:
30.38
1jdvF-4tymA:
30.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 10 THR A  71
GLY A  69
VAL A  59
ALA A  29
ILE A  27
 None
None
CSO  A  60 ( 3.1A)
None
None
 1.07A 1likA-4tymA:
undetectable		 1likA-4tymA:
21.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 11 ARG A 109
THR A 112
GLY A 114
GLU A 201
GLU A 203
ILE A 116
 SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
SO4  A 301 ( 4.4A)
None
 1.33A 1odiA-4tymA:
25.4		 1odiA-4tymA:
35.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		8 / 11 MET A  86
ARG A 109
THR A 112
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
 None
SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
None
SO4  A 301 ( 4.4A)
None
 0.60A 1odiA-4tymA:
25.4		 1odiA-4tymA:
35.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		7 / 11 ARG A 109
THR A 112
GLY A 114
GLU A 201
GLU A 203
SER A 225
ILE A 116
 SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
SO4  A 301 ( 4.4A)
None
None
 1.24A 1odiB-4tymA:
35.2		 1odiB-4tymA:
35.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		8 / 11 MET A  86
ARG A 109
THR A 112
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
 None
SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
None
SO4  A 301 ( 4.4A)
None
 0.58A 1odiB-4tymA:
35.2		 1odiB-4tymA:
35.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		7 / 11 ARG A 109
THR A 112
GLY A 114
GLU A 201
GLU A 203
SER A 225
ILE A 116
 SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
SO4  A 301 ( 4.4A)
None
None
 1.22A 1odiC-4tymA:
35.4		 1odiC-4tymA:
35.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		8 / 11 MET A  86
ARG A 109
THR A 112
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
 None
SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
None
SO4  A 301 ( 4.4A)
None
 0.55A 1odiC-4tymA:
35.4		 1odiC-4tymA:
35.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 11 ARG A 109
THR A 112
GLY A 114
GLU A 201
GLU A 203
ILE A 116
 SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
SO4  A 301 ( 4.4A)
None
 1.31A 1odiD-4tymA:
35.3		 1odiD-4tymA:
35.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		8 / 11 MET A  86
ARG A 109
THR A 112
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
 None
SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
None
SO4  A 301 ( 4.4A)
None
 0.59A 1odiD-4tymA:
35.3		 1odiD-4tymA:
35.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		7 / 11 ARG A 109
THR A 112
GLY A 114
GLU A 201
GLU A 203
SER A 225
ILE A 116
 SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
SO4  A 301 ( 4.4A)
None
None
 1.24A 1odiE-4tymA:
35.2		 1odiE-4tymA:
35.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		8 / 11 MET A  86
ARG A 109
THR A 112
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
 None
SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
None
SO4  A 301 ( 4.4A)
None
 0.54A 1odiE-4tymA:
35.2		 1odiE-4tymA:
35.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		7 / 11 ARG A 109
THR A 112
GLY A 114
GLU A 201
GLU A 203
SER A 225
ILE A 116
 SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
SO4  A 301 ( 4.4A)
None
None
 1.27A 1odiF-4tymA:
35.3		 1odiF-4tymA:
35.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		8 / 11 MET A  86
ARG A 109
THR A 112
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
 None
SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
None
SO4  A 301 ( 4.4A)
None
 0.57A 1odiF-4tymA:
35.3		 1odiF-4tymA:
35.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		7 / 9 MET A  86
ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
 None
SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
None
 0.41A 1pk7A-4tymA:
38.2		 1pk7A-4tymA:
44.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 9 MET A  86
ARG A 109
MET A 202
GLU A 203
SER A 225
ASP A 226
 None
SO4  A 301 (-2.8A)
None
SO4  A 301 ( 4.4A)
None
None
 0.76A 1pk7A-4tymA:
38.2		 1pk7A-4tymA:
44.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		7 / 10 MET A  86
ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
 None
SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
None
 0.51A 1pk7C-4tymA:
37.8		 1pk7C-4tymA:
44.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 10 MET A  86
ARG A 109
GLY A 114
GLU A 203
SER A 225
ASP A 226
 None
SO4  A 301 (-2.8A)
None
SO4  A 301 ( 4.4A)
None
None
 0.84A 1pk7C-4tymA:
37.8		 1pk7C-4tymA:
44.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		7 / 10 MET A  86
ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
 None
SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
None
 0.36A 1pk9A-4tymA:
38.1		 1pk9A-4tymA:
44.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 10 MET A  86
ARG A 109
MET A 202
GLU A 203
SER A 225
ASP A 226
 None
SO4  A 301 (-2.8A)
None
SO4  A 301 ( 4.4A)
None
None
 0.79A 1pk9A-4tymA:
38.1		 1pk9A-4tymA:
44.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		7 / 9 MET A  86
ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
 None
SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
None
 0.41A 1pk9B-4tymA:
38.3		 1pk9B-4tymA:
44.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 9 MET A  86
ARG A 109
MET A 202
GLU A 203
SER A 225
ASP A 226
 None
SO4  A 301 (-2.8A)
None
SO4  A 301 ( 4.4A)
None
None
 0.76A 1pk9B-4tymA:
38.3		 1pk9B-4tymA:
44.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		7 / 11 ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
ILE A 116
 SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
None
None
 1.34A 1pk9C-4tymA:
36.2		 1pk9C-4tymA:
44.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		7 / 11 MET A  86
ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
 None
SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
None
 0.53A 1pk9C-4tymA:
36.2		 1pk9C-4tymA:
44.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 10 ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
ILE A 116
 SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
None
 1.45A 1pw7A-4tymA:
38.3		 1pw7A-4tymA:
45.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		7 / 10 MET A  86
ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
 None
SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
None
 0.35A 1pw7A-4tymA:
38.3		 1pw7A-4tymA:
45.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 10 MET A  86
ARG A 109
MET A 202
GLU A 203
SER A 225
ASP A 226
 None
SO4  A 301 (-2.8A)
None
SO4  A 301 ( 4.4A)
None
None
 0.75A 1pw7A-4tymA:
38.3		 1pw7A-4tymA:
45.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 9 ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
ILE A 116
 SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
None
 1.37A 1pw7B-4tymA:
38.3		 1pw7B-4tymA:
45.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 9 MET A  86
ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
 None
SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
 0.34A 1pw7B-4tymA:
38.3		 1pw7B-4tymA:
45.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_C_RABC647_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 9 MET A  86
GLU A 201
MET A 202
GLU A 203
SER A 225
 None
None
None
SO4  A 301 ( 4.4A)
None
 0.46A 1pw7C-4tymA:
38.0		 1pw7C-4tymA:
45.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_C_RABC647_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 9 MET A  86
MET A 202
GLU A 203
SER A 225
ASP A 226
 None
None
SO4  A 301 ( 4.4A)
None
None
 0.87A 1pw7C-4tymA:
38.0		 1pw7C-4tymA:
45.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 11 ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
ILE A 116
 SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
None
 1.35A 1vhwA-4tymA:
38.9
1vhwD-4tymA:
39.1		 1vhwA-4tymA:
46.21
1vhwD-4tymA:
46.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 11 MET A  86
ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
 None
SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
 0.31A 1vhwA-4tymA:
38.9
1vhwD-4tymA:
39.1		 1vhwA-4tymA:
46.21
1vhwD-4tymA:
46.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_B_ADNB252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 9 MET A  86
ARG A 109
GLY A 114
MET A 202
GLU A 203
 None
SO4  A 301 (-2.8A)
None
None
SO4  A 301 ( 4.4A)
 0.19A 1vhwB-4tymA:
38.8
1vhwF-4tymA:
38.2		 1vhwB-4tymA:
46.21
1vhwF-4tymA:
46.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 11 ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
ILE A 116
 SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
None
 1.42A 1vhwC-4tymA:
39.1
1vhwE-4tymA:
39.0		 1vhwC-4tymA:
46.21
1vhwE-4tymA:
46.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 11 MET A  86
ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
 None
SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
 0.31A 1vhwC-4tymA:
39.1
1vhwE-4tymA:
39.0		 1vhwC-4tymA:
46.21
1vhwE-4tymA:
46.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 11 ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
ILE A 116
 SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
None
 1.40A 1vhwA-4tymA:
38.9
1vhwD-4tymA:
39.1		 1vhwA-4tymA:
46.21
1vhwD-4tymA:
46.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 11 MET A  86
ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
 None
SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
 0.31A 1vhwA-4tymA:
38.9
1vhwD-4tymA:
39.1		 1vhwA-4tymA:
46.21
1vhwD-4tymA:
46.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 11 ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
ILE A 116
 SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
None
 1.35A 1vhwC-4tymA:
39.1
1vhwE-4tymA:
39.0		 1vhwC-4tymA:
46.21
1vhwE-4tymA:
46.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 11 MET A  86
ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
 None
SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
 0.30A 1vhwC-4tymA:
39.1
1vhwE-4tymA:
39.0		 1vhwC-4tymA:
46.21
1vhwE-4tymA:
46.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 10 MET A  86
ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
 None
SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
 0.31A 1vhwB-4tymA:
38.8
1vhwF-4tymA:
38.2		 1vhwB-4tymA:
46.21
1vhwF-4tymA:
46.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		8 / 10 MET A  86
ARG A 109
THR A 112
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
 None
SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
None
SO4  A 301 ( 4.4A)
None
 0.41A 1z35A-4tymA:
37.3		 1z35A-4tymA:
42.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 10 MET A 202
ARG A 109
THR A 112
GLU A 203
SER A 225
 None
SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
SO4  A 301 ( 4.4A)
None
 1.43A 1z35A-4tymA:
37.3		 1z35A-4tymA:
42.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		8 / 9 MET A  86
ARG A 109
THR A 112
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
 None
SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
None
SO4  A 301 ( 4.4A)
None
 0.44A 1z37A-4tymA:
37.1		 1z37A-4tymA:
42.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 9 MET A 202
ARG A 109
THR A 112
GLU A 203
SER A 225
 None
SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
SO4  A 301 ( 4.4A)
None
 1.45A 1z37A-4tymA:
37.1		 1z37A-4tymA:
42.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		7 / 11 MET A  86
ARG A 109
THR A 112
GLY A 114
GLU A 201
MET A 202
GLU A 203
 None
SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
None
SO4  A 301 ( 4.4A)
 0.50A 2ac7A-4tymA:
38.2
2ac7B-4tymA:
38.3		 2ac7A-4tymA:
53.49
2ac7B-4tymA:
53.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		7 / 11 MET A  86
ARG A 109
THR A 112
GLY A 114
GLU A 201
MET A 202
GLU A 203
 None
SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
None
SO4  A 301 ( 4.4A)
 0.51A 2ac7A-4tymA:
38.2
2ac7B-4tymA:
38.3		 2ac7A-4tymA:
53.49
2ac7B-4tymA:
53.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		4 / 6 LEU A  55
LEU A 252
PRO A  41
VAL A 110
 None
 1.18A 2dqyC-4tymA:
undetectable		 2dqyC-4tymA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 12 VAL A 126
ASP A 226
ILE A 224
ASN A 227
GLU A 124
 None
 1.48A 3jb3A-4tymA:
undetectable		 3jb3A-4tymA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 10 THR A 112
GLY A 114
PHE A 181
GLU A 201
MET A 202
 SO4  A 301 (-3.7A)
None
None
None
None
 0.68A 3kvrA-4tymA:
25.2		 3kvrA-4tymA:
27.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 10 THR A 112
GLY A 114
PHE A 181
GLU A 201
MET A 202
 SO4  A 301 (-3.7A)
None
None
None
None
 0.65A 3kvrB-4tymA:
25.0		 3kvrB-4tymA:
27.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		4 / 6 ALA A 199
ILE A 224
GLU A 201
ALA A 128
 None
 0.90A 3r9sC-4tymA:
undetectable		 3r9sC-4tymA:
23.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_A_ADNA251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 9 MET A  86
ARG A 109
GLU A 201
MET A 202
GLU A 203
 None
SO4  A 301 (-2.8A)
None
None
SO4  A 301 ( 4.4A)
 0.53A 3u40A-4tymA:
36.4
3u40F-4tymA:
18.8		 3u40A-4tymA:
41.63
3u40F-4tymA:
41.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_B_ADNB251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 10 MET A  86
ARG A 109
GLU A 201
MET A 202
GLU A 203
 None
SO4  A 301 (-2.8A)
None
None
SO4  A 301 ( 4.4A)
 0.51A 3u40B-4tymA:
36.3
3u40C-4tymA:
22.7		 3u40B-4tymA:
41.63
3u40C-4tymA:
41.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 12 MET A  86
ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
 None
SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
 0.43A 3u40B-4tymA:
36.3
3u40C-4tymA:
22.7		 3u40B-4tymA:
41.63
3u40C-4tymA:
41.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 11 MET A  86
ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
 None
SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
 0.42A 3u40D-4tymA:
36.3
3u40E-4tymA:
35.6		 3u40D-4tymA:
41.63
3u40E-4tymA:
41.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 12 MET A  86
ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
 None
SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
 0.47A 3u40D-4tymA:
36.3
3u40E-4tymA:
35.6		 3u40D-4tymA:
41.63
3u40E-4tymA:
41.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_F_ADNF251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 10 MET A  86
ARG A 109
GLU A 201
MET A 202
GLU A 203
 None
SO4  A 301 (-2.8A)
None
None
SO4  A 301 ( 4.4A)
 0.48A 3u40A-4tymA:
36.4
3u40F-4tymA:
18.8		 3u40A-4tymA:
41.63
3u40F-4tymA:
41.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_F_ADNF251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 10 MET A  86
ARG A 109
MET A 202
GLU A 203
ASP A 226
 None
SO4  A 301 (-2.8A)
None
SO4  A 301 ( 4.4A)
None
 0.60A 3u40A-4tymA:
36.4
3u40F-4tymA:
18.8		 3u40A-4tymA:
41.63
3u40F-4tymA:
41.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 11 ARG A 109
THR A 112
GLY A 114
GLU A 201
GLU A 203
ILE A 116
 SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
SO4  A 301 ( 4.4A)
None
 1.36A 3uawA-4tymA:
25.4		 3uawA-4tymA:
53.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 11 ARG A 109
THR A 112
VAL A 126
SER A 225
ILE A 120
 SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
None
 1.19A 3uawA-4tymA:
25.4		 3uawA-4tymA:
53.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		8 / 11 MET A  86
ARG A 109
THR A 112
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
 None
SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
None
SO4  A 301 ( 4.4A)
None
 0.54A 3uawA-4tymA:
25.4		 3uawA-4tymA:
53.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 10 ARG A 109
THR A 112
GLY A 114
GLU A 201
GLU A 203
ILE A 116
 SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
SO4  A 301 ( 4.4A)
None
 1.37A 3uayA-4tymA:
39.8		 3uayA-4tymA:
53.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		7 / 10 MET A  86
ARG A 109
THR A 112
GLY A 114
GLU A 201
MET A 202
GLU A 203
 None
SO4  A 301 (-2.8A)
SO4  A 301 (-3.7A)
None
None
None
SO4  A 301 ( 4.4A)
 0.46A 3uayA-4tymA:
39.8		 3uayA-4tymA:
53.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		4 / 7 PRO A  44
MET A  86
ARG A  46
GLY A 111
 None
None
None
SO4  A 301 (-3.6A)
 1.36A 3ucbB-4tymA:
undetectable		 3ucbB-4tymA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BWL_C_MN9C1297_0
(N-ACETYLNEURAMINATE
LYASE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 10 ILE A  91
LEU A 207
THR A  84
GLY A  42
GLY A 111
 None
None
None
SO4  A 301 (-3.3A)
SO4  A 301 (-3.6A)
 1.09A 4bwlC-4tymA:
undetectable		 4bwlC-4tymA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 12 VAL A 175
LEU A 176
SER A 177
GLY A 114
ALA A 113
 None
 1.09A 4coxC-4tymA:
undetectable		 4coxC-4tymA:
16.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		8 / 11 MET A  86
ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
ASP A 226
 None
SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
None
None
 0.76A 4d9hA-4tymA:
38.0		 4d9hA-4tymA:
52.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 9 MET A  86
GLY A 114
MET A 202
GLU A 203
SER A 225
ASP A 226
 None
None
None
SO4  A 301 ( 4.4A)
None
None
 0.97A 4da6A-4tymA:
37.8		 4da6A-4tymA:
52.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		7 / 10 MET A  86
ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
 None
SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
None
 0.51A 4da7A-4tymA:
37.9		 4da7A-4tymA:
52.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		8 / 11 MET A  86
ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
ASP A 226
 None
SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
None
None
 0.87A 4danA-4tymA:
37.8		 4danA-4tymA:
52.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		7 / 12 ARG A 109
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
ASP A 226
 SO4  A 301 (-2.8A)
None
None
None
SO4  A 301 ( 4.4A)
None
None
 0.87A 4danA-4tymA:
37.8
4danB-4tymA:
37.7		 4danA-4tymA:
52.29
4danB-4tymA:
52.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 12 VAL A 175
LEU A 176
SER A 177
GLY A 114
ALA A 113
 None
 1.06A 4otyA-4tymA:
undetectable		 4otyA-4tymA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 12 VAL A 175
LEU A 176
SER A 177
LEU A 228
GLY A 114
ALA A 113
 None
 1.12A 4otyB-4tymA:
undetectable		 4otyB-4tymA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 12 VAL A 175
LEU A 176
SER A 177
GLY A 114
ALA A 113
 None
 1.04A 4rrwD-4tymA:
undetectable		 4rrwD-4tymA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 12 VAL A 175
LEU A 176
SER A 177
GLY A 114
ALA A 113
 None
 1.04A 4rrzD-4tymA:
undetectable		 4rrzD-4tymA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 9 VAL A 175
LEU A 176
SER A 177
GLY A 114
ALA A 113
 None
 1.06A 4rs0A-4tymA:
1.4		 4rs0A-4tymA:
16.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 9 MET A  86
ARG A 109
GLY A 114
MET A 202
GLU A 203
 None
SO4  A 301 (-2.8A)
None
None
SO4  A 301 ( 4.4A)
 0.16A 5i3cA-4tymA:
38.3		 5i3cA-4tymA:
44.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		5 / 10 MET A  86
GLY A 114
GLU A 201
MET A 202
GLU A 203
 None
None
None
None
SO4  A 301 ( 4.4A)
 0.38A 5i3cB-4tymA:
38.4		 5i3cB-4tymA:
44.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 11 MET A  86
GLY A 114
GLU A 201
MET A 202
GLU A 203
ASP A 226
 None
None
None
None
SO4  A 301 ( 4.4A)
None
 0.74A 5i3cC-4tymA:
38.5		 5i3cC-4tymA:
44.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE
(Streptococcus
agalactiae) 		6 / 11 MET A  86
GLY A 114
GLU A 201
MET A 202
GLU A 203
SER A 225
 None
None
None
None
SO4  A 301 ( 4.4A)
None
 0.41A 5i3cC-4tymA:
38.5		 5i3cC-4tymA:
44.91