SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4tyz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_B_017B203_1
(HIV-1 PROTEASE)		 4tyz UNCHARACTERIZED
PROTEIN
(Leishmania
infantum) 		4 / 7 GLU A 623
PRO A 631
ARG A 627
GLY A 624
 None
 1.31A 2hs1B-4tyzA:
undetectable		 2hs1B-4tyzA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 4tyz UNCHARACTERIZED
PROTEIN
(Leishmania
infantum) 		4 / 7 GLU A 681
ASP A 680
TRP A 663
SER A 676
 None
 1.46A 3dzgA-4tyzA:
undetectable		 3dzgA-4tyzA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 4tyz UNCHARACTERIZED
PROTEIN
(Leishmania
infantum) 		5 / 12 ALA A 719
GLY A 655
SER A 668
SER A 641
TYR A 656
 None
 1.28A 5hfjB-4tyzA:
undetectable		 5hfjB-4tyzA:
18.86