SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4u13'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DZ6_A_CAMA502_0 (CYTOCHROME P450-CAM)	4u13	PUTATIVE POLYKETIDE CYCLASE SMA1630 (Sinorhizobium meliloti)	4 / 5	PHE A 11 TYR A 10 LEU A 103 VAL A 78	None	1.26A	1dz6A-4u13A: undetectable	1dz6A-4u13A: 16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z2B_C_VLBC800_2 (TUBULIN ALPHA CHAIN)	4u13	PUTATIVE POLYKETIDE CYCLASE SMA1630 (Sinorhizobium meliloti)	4 / 5	PRO A 4 VAL A 7 ASN A 8 VAL A 74	None	1.09A	1z2bC-4u13A: undetectable	1z2bC-4u13A: 15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HA2_A_SCKA901_1 (ACETYLCHOLINESTERASE)	4u13	PUTATIVE POLYKETIDE CYCLASE SMA1630 (Sinorhizobium meliloti)	4 / 8	TYR A 10 ASP A 14 TYR A 91 TYR A 58	None	1.48A	2ha2A-4u13A: undetectable	2ha2A-4u13A: 13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HA2_B_SCKB951_1 (ACETYLCHOLINESTERASE)	4u13	PUTATIVE POLYKETIDE CYCLASE SMA1630 (Sinorhizobium meliloti)	4 / 8	TYR A 10 ASP A 14 TYR A 91 TYR A 58	None	1.41A	2ha2B-4u13A: undetectable	2ha2B-4u13A: 13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AX9_B_SALB1340_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	4u13	PUTATIVE POLYKETIDE CYCLASE SMA1630 (Sinorhizobium meliloti)	4 / 8	LEU A 3 SER A 0 PHE A -2 ALA A 76	None	0.96A	3ax9B-4u13A: undetectable	3ax9B-4u13A: 6.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3Q5R_A_KANA2002_1 (MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR)	4u13	PUTATIVE POLYKETIDE CYCLASE SMA1630 (Sinorhizobium meliloti)	5 / 11	VAL A 78 TYR A 58 PHE A 93 TYR A 10 ILE A 105	None	1.14A	3q5rA-4u13A: undetectable	3q5rA-4u13A: 16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L4E_A_CAMA503_0 (CAMPHOR 5-MONOOXYGENASE)	4u13	PUTATIVE POLYKETIDE CYCLASE SMA1630 (Sinorhizobium meliloti)	4 / 8	PHE A 11 TYR A 10 LEU A 103 VAL A 78	None	1.15A	4l4eA-4u13A: undetectable	4l4eA-4u13A: 16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PCU_A_SAMA603_0 (CYSTATHIONINE BETA-SYNTHASE)	4u13	PUTATIVE POLYKETIDE CYCLASE SMA1630 (Sinorhizobium meliloti)	4 / 7	PHE A 11 ASP A 12 THR A 25 ILE A 6	None	0.97A	4pcuA-4u13A: undetectable	4pcuA-4u13A: 12.60

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DZ6_A_CAMA502_0","CYTOCHROME P450-CAM","4u13","PUTATIVE POLYKETIDE CYCLASE SMA1630","Sinorhizobium meliloti",4,"PHE A  11;TYR A  10;LEU A 103;VAL A  78","None","1.26A","1dz6A-4u13A:undetectable","1dz6A-4u13A:16.41"],["1Z2B_C_VLBC800_2","TUBULIN ALPHA CHAIN","4u13","PUTATIVE POLYKETIDE CYCLASE SMA1630","Sinorhizobium meliloti",4,"PRO A   4;VAL A   7;ASN A   8;VAL A  74","None","1.09A","1z2bC-4u13A:undetectable","1z2bC-4u13A:15.50"],["2HA2_A_SCKA901_1","ACETYLCHOLINESTERASE","4u13","PUTATIVE POLYKETIDE CYCLASE SMA1630","Sinorhizobium meliloti",4,"TYR A  10;ASP A  14;TYR A  91;TYR A  58","None","1.48A","2ha2A-4u13A:undetectable","2ha2A-4u13A:13.33"],["2HA2_B_SCKB951_1","ACETYLCHOLINESTERASE","4u13","PUTATIVE POLYKETIDE CYCLASE SMA1630","Sinorhizobium meliloti",4,"TYR A  10;ASP A  14;TYR A  91;TYR A  58","None","1.41A","2ha2B-4u13A:undetectable","2ha2B-4u13A:13.33"],["3AX9_B_SALB1340_1","XANTHINE DEHYDROGENASE\/OXIDASE","4u13","PUTATIVE POLYKETIDE CYCLASE SMA1630","Sinorhizobium meliloti",4,"LEU A   3;SER A   0;PHE A  -2;ALA A  76","None","0.96A","3ax9B-4u13A:undetectable","3ax9B-4u13A:6.39"],["3Q5R_A_KANA2002_1","MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR","4u13","PUTATIVE POLYKETIDE CYCLASE SMA1630","Sinorhizobium meliloti",5,"VAL A  78;TYR A  58;PHE A  93;TYR A  10;ILE A 105","None","1.14A","3q5rA-4u13A:undetectable","3q5rA-4u13A:16.04"],["4L4E_A_CAMA503_0","CAMPHOR 5-MONOOXYGENASE","4u13","PUTATIVE POLYKETIDE CYCLASE SMA1630","Sinorhizobium meliloti",4,"PHE A  11;TYR A  10;LEU A 103;VAL A  78","None","1.15A","4l4eA-4u13A:undetectable","4l4eA-4u13A:16.37"],["4PCU_A_SAMA603_0","CYSTATHIONINE BETA-SYNTHASE","4u13","PUTATIVE POLYKETIDE CYCLASE SMA1630","Sinorhizobium meliloti",4,"PHE A  11;ASP A  12;THR A  25;ILE A   6","None","0.97A","4pcuA-4u13A:undetectable","4pcuA-4u13A:12.60"]]