SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4u1g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 4u1g RETICULOCYTE BINDING
PROTEIN 5
(Plasmodium
falciparum) 		5 / 12 GLY A 336
ILE A 193
SER A 192
ALA A 205
ILE A 213
 None
 1.16A 1ve3B-4u1gA:
undetectable		 1ve3B-4u1gA:
18.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KDM_H_TESH226_1
(IMMUNOGLOBULIN HEAVY
CHAIN
IMMUNOGLOBULIN LIGHT
CHAIN)		 4u1g QA1 MONOCLONAL
ANTIBODY HEAVY CHAIN
(Mus
musculus) 		5 / 9 TRP B  47
TYR B  59
ASP B  99
TYR B  33
MET B 109
 None
 1.45A 3kdmH-4u1gB:
25.4
3kdmL-4u1gB:
15.3		 3kdmH-4u1gB:
65.65
3kdmL-4u1gB:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 4u1g QA1 MONOCLONAL
ANTIBODY HEAVY CHAIN
(Mus
musculus) 		3 / 3 SER B 170
SER B 169
HIS B 173
 None
 0.80A 3mzeA-4u1gB:
1.3		 3mzeA-4u1gB:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 4u1g QA1 MONOCLONAL
ANTIBODY HEAVY CHAIN
(Mus
musculus) 		3 / 3 ASP B  99
GLY B 106
TYR B  33
 None
 0.69A 3w9tC-4u1gB:
undetectable		 3w9tC-4u1gB:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 4u1g QA1 MONOCLONAL
ANTIBODY HEAVY CHAIN
(Mus
musculus) 		3 / 3 ASP B  99
GLY B 106
TYR B  33
 None
 0.69A 3w9tG-4u1gB:
undetectable		 3w9tG-4u1gB:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 4u1g QA1 MONOCLONAL
ANTIBODY HEAVY CHAIN
RETICULOCYTE BINDING
PROTEIN 5
(Mus
musculus;
Plasmodium
falciparum) 		4 / 7 LYS B 103
TYR A 346
LEU A 455
PHE A 450
 None
 1.24A 4yv5A-4u1gB:
undetectable		 4yv5A-4u1gB:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 4u1g QA1 MONOCLONAL
ANTIBODY HEAVY CHAIN
(Mus
musculus) 		3 / 3 SER B 212
ALA B 207
VAL B 206
 None
 0.54A 5xiwC-4u1gB:
undetectable		 5xiwC-4u1gB:
18.44