SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4u39'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
3 / 3 THR A 109
PRO A  75
THR A 111
PO4  A 401 (-4.1A)
None
None
0.87A 1a7yB-4u39A:
undetectable
1a7yB-4u39A:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
6 / 12 GLY A  18
ILE A  89
ALA A 113
GLY A 110
ALA A 114
ILE A 117
None
None
None
PO4  A 401 (-3.8A)
None
None
1.41A 1bx4A-4u39A:
6.9
1bx4A-4u39A:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
3 / 3 THR A 109
PRO A  75
THR A 111
PO4  A 401 (-4.1A)
None
None
0.86A 1dscC-4u39A:
undetectable
1dscC-4u39A:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 9 LEU A 261
ILE A 311
LEU A 127
GLY A 130
ALA A 224
None
1.28A 1e7aA-4u39A:
undetectable
1e7aA-4u39A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
3 / 3 THR A 111
THR A 109
PRO A  75
None
PO4  A 401 (-4.1A)
None
0.88A 1fjaC-4u39A:
undetectable
1fjaC-4u39A:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
3 / 3 THR A 111
THR A 109
PRO A  75
None
PO4  A 401 (-4.1A)
None
0.88A 1fjaD-4u39A:
undetectable
1fjaD-4u39A:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 12 ILE A 197
ILE A  89
ILE A  17
VAL A 194
ILE A  41
None
1.27A 1r5lA-4u39A:
undetectable
1r5lA-4u39A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 8 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
0.95A 1rxcB-4u39A:
3.9
1rxcB-4u39A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 7 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
0.98A 1rxcC-4u39A:
undetectable
1rxcC-4u39A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 7 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
1.03A 1rxcD-4u39A:
2.4
1rxcD-4u39A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 8 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
0.95A 1rxcE-4u39A:
undetectable
1rxcE-4u39A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 7 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
0.99A 1rxcF-4u39A:
4.1
1rxcF-4u39A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 8 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
0.98A 1rxcI-4u39A:
undetectable
1rxcI-4u39A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 8 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
0.97A 1rxcK-4u39A:
3.3
1rxcK-4u39A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 7 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
0.97A 1rxcL-4u39A:
3.8
1rxcL-4u39A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_B_GBNB914_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 10 GLY A  18
GLY A 110
THR A 109
ALA A 113
ALA A 114
None
PO4  A 401 (-3.8A)
PO4  A 401 (-4.1A)
None
None
1.01A 2ej3B-4u39A:
undetectable
2ej3B-4u39A:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA802_0
(FERROCHELATASE)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 6 MET A 226
ARG A  29
ARG A 191
VAL A 307
None
1.13A 2qd4A-4u39A:
2.7
2qd4A-4u39A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
6 / 12 GLY A  18
GLY A  20
ALA A  49
VAL A  16
ASN A  25
VAL A 194
None
PO4  A 401 (-3.3A)
None
None
None
None
1.45A 2zulA-4u39A:
3.5
2zulA-4u39A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
6 / 12 GLY A  18
GLY A  20
ALA A  49
VAL A  16
ASN A  25
VAL A 194
None
PO4  A 401 (-3.3A)
None
None
None
None
1.39A 3dmfA-4u39A:
3.2
3dmfA-4u39A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
6 / 12 GLY A  18
GLY A  20
ALA A  49
VAL A  16
ASN A  25
VAL A 194
None
PO4  A 401 (-3.3A)
None
None
None
None
1.40A 3dmhA-4u39A:
3.3
3dmhA-4u39A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 12 GLY A  20
ASN A  44
GLY A 130
ASN A  25
THR A 133
PO4  A 401 (-3.3A)
PO4  A 401 ( 4.2A)
None
None
None
1.11A 3eeyA-4u39A:
4.2
3eeyA-4u39A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 12 GLY A  20
ASN A  44
GLY A 130
ASN A  25
THR A 133
PO4  A 401 (-3.3A)
PO4  A 401 ( 4.2A)
None
None
None
1.10A 3eeyB-4u39A:
undetectable
3eeyB-4u39A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 12 GLY A  20
ASN A  44
GLY A 130
ASN A  25
THR A 133
PO4  A 401 (-3.3A)
PO4  A 401 ( 4.2A)
None
None
None
1.10A 3eeyC-4u39A:
4.3
3eeyC-4u39A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 12 GLY A  20
ASN A  44
GLY A 130
ASN A  25
THR A 133
PO4  A 401 (-3.3A)
PO4  A 401 ( 4.2A)
None
None
None
1.10A 3eeyD-4u39A:
4.5
3eeyD-4u39A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 12 GLY A  20
ASN A  44
GLY A 130
ASN A  25
THR A 133
PO4  A 401 (-3.3A)
PO4  A 401 ( 4.2A)
None
None
None
1.11A 3eeyE-4u39A:
4.2
3eeyE-4u39A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 12 GLY A  20
ASN A  44
GLY A 130
ASN A  25
THR A 133
PO4  A 401 (-3.3A)
PO4  A 401 ( 4.2A)
None
None
None
1.11A 3eeyH-4u39A:
4.2
3eeyH-4u39A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 12 GLY A  20
ASN A  44
GLY A 130
ASN A  25
THR A 133
PO4  A 401 (-3.3A)
PO4  A 401 ( 4.2A)
None
None
None
1.10A 3eeyI-4u39A:
4.5
3eeyI-4u39A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 12 GLY A  20
ASN A  44
GLY A 130
ASN A  25
THR A 133
PO4  A 401 (-3.3A)
PO4  A 401 ( 4.2A)
None
None
None
1.13A 3eeyJ-4u39A:
4.4
3eeyJ-4u39A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 6 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
0.98A 3kvvA-4u39A:
2.1
3kvvA-4u39A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 6 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
0.98A 3kvvB-4u39A:
2.2
3kvvB-4u39A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 6 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
0.98A 3kvvC-4u39A:
undetectable
3kvvC-4u39A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 6 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
0.95A 3kvvD-4u39A:
2.5
3kvvD-4u39A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 6 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
0.97A 3kvvE-4u39A:
undetectable
3kvvE-4u39A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 6 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
1.00A 3kvvF-4u39A:
undetectable
3kvvF-4u39A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA271_0
(PROTEIN SSM1)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 5 GLY A 106
GLU A 139
GLY A 104
PRO A 135
None
0.97A 3onnA-4u39A:
5.8
3onnA-4u39A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 6 THR A 309
ILE A 311
THR A 102
PHE A 100
None
1.02A 4acbC-4u39A:
5.0
4acbC-4u39A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
6 / 12 ILE A 120
GLY A 112
THR A 109
VAL A  43
ILE A  17
VAL A  19
None
None
PO4  A 401 (-4.1A)
None
None
None
1.36A 4c9lA-4u39A:
undetectable
4c9lA-4u39A:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
6 / 12 ILE A 120
GLY A 112
THR A 109
VAL A  43
ILE A  17
VAL A  19
None
None
PO4  A 401 (-4.1A)
None
None
None
1.36A 4c9lB-4u39A:
undetectable
4c9lB-4u39A:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
6 / 12 ILE A 120
GLY A 112
THR A 109
VAL A  43
ILE A  17
VAL A  19
None
None
PO4  A 401 (-4.1A)
None
None
None
1.35A 4c9oA-4u39A:
undetectable
4c9oA-4u39A:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
6 / 12 ILE A 120
GLY A 112
THR A 109
VAL A  43
ILE A  17
VAL A  19
None
None
PO4  A 401 (-4.1A)
None
None
None
1.34A 4c9oB-4u39A:
undetectable
4c9oB-4u39A:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 8 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
0.98A 4e1vA-4u39A:
undetectable
4e1vA-4u39A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 7 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
0.93A 4e1vB-4u39A:
3.5
4e1vB-4u39A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 8 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
0.97A 4e1vD-4u39A:
2.2
4e1vD-4u39A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 6 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
0.98A 4e1vF-4u39A:
3.5
4e1vF-4u39A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 8 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
0.97A 4e1vG-4u39A:
undetectable
4e1vG-4u39A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 8 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
0.93A 4e1vH-4u39A:
3.6
4e1vH-4u39A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 6 MET A 226
ARG A  29
ARG A 191
VAL A 307
None
1.17A 4mk4B-4u39A:
3.3
4mk4B-4u39A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_2
(PROTEASE)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 11 GLY A 227
VAL A 131
GLY A 196
THR A 160
ILE A 162
None
0.91A 4njvB-4u39A:
undetectable
4njvB-4u39A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_1
(PROTEASE)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 11 GLY A 227
VAL A 131
GLY A 196
THR A 160
ILE A 162
None
0.93A 4njvC-4u39A:
undetectable
4njvC-4u39A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 9 ALA A 126
ILE A 197
VAL A 194
GLY A 130
VAL A  16
None
1.27A 4r20B-4u39A:
undetectable
4r20B-4u39A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 12 ALA A  71
GLY A  20
ILE A 151
MET A 105
GLY A 106
None
PO4  A 401 (-3.3A)
None
None
None
0.97A 4r29D-4u39A:
undetectable
4r29D-4u39A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 12 GLU A  32
ASP A 187
LEU A 190
GLY A  18
ALA A 103
None
1.22A 4xe5A-4u39A:
3.2
4xe5A-4u39A:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 12 GLY A  78
ILE A  61
THR A 109
GLY A  20
GLY A 150
None
None
PO4  A 401 (-4.1A)
PO4  A 401 (-3.3A)
None
0.94A 5d4uA-4u39A:
3.8
5d4uA-4u39A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 12 GLY A  78
ILE A  61
THR A 109
GLY A  20
GLY A 150
None
None
PO4  A 401 (-4.1A)
PO4  A 401 (-3.3A)
None
0.89A 5d4uD-4u39A:
undetectable
5d4uD-4u39A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 9 ILE A 311
GLN A 192
ASN A 263
LEU A 200
LEU A 209
None
1.46A 5fhzB-4u39A:
3.0
5fhzB-4u39A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_ACTD305_0
(CARBONIC ANHYDRASE 4)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
4 / 5 PRO A 115
ALA A 118
ALA A 157
LEU A 161
None
0.75A 5jncD-4u39A:
undetectable
5jncD-4u39A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 12 GLY A  18
VAL A  16
PHE A 100
VAL A  99
MET A 105
None
1.18A 5n0rA-4u39A:
1.9
5n0rA-4u39A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 12 GLY A  18
VAL A  16
PHE A 100
VAL A  99
MET A 105
None
1.15A 5n0wA-4u39A:
2.6
5n0wA-4u39A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)
4u39 CELL DIVISION
PROTEIN FTSZ

(Bacillus
subtilis)
5 / 12 GLY A  18
VAL A 101
GLY A 104
GLY A  20
ASP A 187
None
None
None
PO4  A 401 (-3.3A)
None
1.19A 5x7fA-4u39A:
4.0
5x7fA-4u39A:
23.78