SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4u3g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 4u3g BACTERIOFERRITIN
(Escherichia
coli) 		4 / 6 ARG A  30
ILE A  49
PHE A  26
GLU A  47
 None
 1.48A 1nsiC-4u3gA:
undetectable
1nsiD-4u3gA:
undetectable		 1nsiC-4u3gA:
18.70
1nsiD-4u3gA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 4u3g BACTERIOFERRITIN
(Escherichia
coli) 		4 / 6 PHE A  26
GLU A  47
ARG A  30
ILE A  49
 None
 1.49A 1nsiC-4u3gA:
undetectable
1nsiD-4u3gA:
undetectable		 1nsiC-4u3gA:
18.70
1nsiD-4u3gA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 4u3g BACTERIOFERRITIN
(Escherichia
coli) 		6 / 11 GLU A  51
HIS A  54
LEU A  93
GLU A  94
ILE A 123
GLU A 127
 None
 0.86A 1rnrA-4u3gA:
10.2		 1rnrA-4u3gA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 4u3g BACTERIOFERRITIN
(Escherichia
coli) 		7 / 12 GLU A  51
HIS A  54
TYR A  58
LEU A  93
GLU A  94
ILE A 123
GLU A 127
 None
 0.92A 1rnrB-4u3gA:
10.2		 1rnrB-4u3gA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 4u3g BACTERIOFERRITIN
(Escherichia
coli) 		4 / 7 ARG A  30
ILE A  49
PHE A  26
GLU A  47
 None
 1.48A 2nsiA-4u3gA:
undetectable
2nsiB-4u3gA:
undetectable		 2nsiA-4u3gA:
18.70
2nsiB-4u3gA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 4u3g BACTERIOFERRITIN
(Escherichia
coli) 		4 / 7 PHE A  26
GLU A  47
ARG A  30
ILE A  49
 None
 1.48A 2nsiA-4u3gA:
undetectable
2nsiB-4u3gA:
undetectable		 2nsiA-4u3gA:
18.70
2nsiB-4u3gA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 4u3g BACTERIOFERRITIN
(Escherichia
coli) 		4 / 7 ARG A  30
ILE A  49
PHE A  26
GLU A  47
 None
 1.47A 2nsiC-4u3gA:
undetectable
2nsiD-4u3gA:
undetectable		 2nsiC-4u3gA:
18.70
2nsiD-4u3gA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 4u3g BACTERIOFERRITIN
(Escherichia
coli) 		4 / 7 PHE A  26
GLU A  47
ARG A  30
ILE A  49
 None
 1.47A 2nsiC-4u3gA:
undetectable
2nsiD-4u3gA:
undetectable		 2nsiC-4u3gA:
18.70
2nsiD-4u3gA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 4u3g BACTERIOFERRITIN
(Escherichia
coli) 		4 / 8 SER A 116
ILE A   8
LEU A  11
GLY A  67
 None
 0.71A 3dcjB-4u3gA:
undetectable		 3dcjB-4u3gA:
17.86