SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4u3q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 4u3q 17 KDA LIPOPROTEIN
(Treponema
pallidum) 		4 / 7 GLU A  96
TYR A  98
LEU A  81
THR A  39
 None
 1.15A 1rmtB-4u3qA:
undetectable		 1rmtB-4u3qA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 4u3q 17 KDA LIPOPROTEIN
(Treponema
pallidum) 		4 / 5 TYR A  67
LYS A  51
LEU A  81
GLU A  96
 None
 1.44A 4olaA-4u3qA:
undetectable		 4olaA-4u3qA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_ACTC202_0
(RETINOL-BINDING
PROTEIN 2)		 4u3q 17 KDA LIPOPROTEIN
(Treponema
pallidum) 		4 / 6 TYR A  98
GLU A  53
THR A  39
LEU A  81
 None
 0.94A 4qzuC-4u3qA:
2.2		 4qzuC-4u3qA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 4u3q 17 KDA LIPOPROTEIN
(Treponema
pallidum) 		4 / 8 GLU A  80
GLY A  69
THR A  40
TYR A 108
 None
 0.95A 5flcB-4u3qA:
undetectable		 5flcB-4u3qA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 4u3q 17 KDA LIPOPROTEIN
(Treponema
pallidum) 		4 / 8 GLU A  80
GLY A  69
THR A  40
TYR A 108
 None
 0.95A 5flcF-4u3qA:
undetectable		 5flcF-4u3qA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 4u3q 17 KDA LIPOPROTEIN
(Treponema
pallidum) 		4 / 5 TYR A  67
LYS A  51
LEU A  81
GLU A  96
 None
 1.19A 5js1A-4u3qA:
undetectable		 5js1A-4u3qA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 4u3q 17 KDA LIPOPROTEIN
(Treponema
pallidum) 		4 / 5 TYR A  67
LYS A  51
LEU A  81
GLU A  96
 None
 1.26A 5weaA-4u3qA:
undetectable		 5weaA-4u3qA:
9.68