SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4u3t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		6 / 12 SER A 310
LYS A 313
SER A 362
ASN A 364
THR A 483
GLY A 499
 None
 0.73A 1i2wA-4u3tA:
16.0		 1i2wA-4u3tA:
28.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		6 / 12 SER A 310
LYS A 313
SER A 362
ASN A 364
THR A 483
GLY A 499
 None
 0.71A 1i2wB-4u3tA:
16.0		 1i2wB-4u3tA:
28.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		6 / 12 SER A 310
LYS A 313
SER A 362
ASN A 364
THR A 483
GLY A 499
 None
 0.76A 1ymxA-4u3tA:
16.4		 1ymxA-4u3tA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		4 / 5 LEU A 473
ILE A 317
LEU A 370
ARG A 373
 None
 0.98A 2byoA-4u3tA:
undetectable		 2byoA-4u3tA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_B_REAB1445_1
(PUTATIVE CYTOCHROME
P450 120)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 12 ALA A 318
ALA A 437
THR A 436
GLY A 520
PRO A 527
 None
 1.03A 2ve3B-4u3tA:
undetectable		 2ve3B-4u3tA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		4 / 4 THR A 539
VAL A 548
GLY A 263
THR A 264
 None
 0.89A 3cflA-4u3tA:
undetectable		 3cflA-4u3tA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_B_LOCB700_2
(TUBULIN BETA-2B
CHAIN)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 11 LEU A 386
ALA A 434
LEU A 438
ALA A 318
LYS A 319
 None
 1.17A 3e22B-4u3tA:
undetectable		 3e22B-4u3tA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 11 LEU A 386
ALA A 434
LEU A 438
ALA A 318
LYS A 319
 None
 1.19A 3e22D-4u3tA:
undetectable		 3e22D-4u3tA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		4 / 4 GLY A 516
VAL A 548
GLY A 484
THR A 485
 None
 0.91A 3ib2A-4u3tA:
undetectable		 3ib2A-4u3tA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 11 PHE A 420
ASP A 346
SER A 363
SER A 368
ILE A 413
 None
 1.17A 3ko0A-4u3tA:
undetectable
3ko0B-4u3tA:
undetectable
3ko0C-4u3tA:
undetectable
3ko0D-4u3tA:
undetectable		 3ko0A-4u3tA:
15.76
3ko0B-4u3tA:
15.76
3ko0C-4u3tA:
15.76
3ko0D-4u3tA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 11 SER A 368
ILE A 413
PHE A 420
ASP A 346
SER A 363
 None
 1.20A 3ko0C-4u3tA:
undetectable
3ko0D-4u3tA:
undetectable
3ko0E-4u3tA:
undetectable
3ko0F-4u3tA:
undetectable		 3ko0C-4u3tA:
15.76
3ko0D-4u3tA:
15.76
3ko0E-4u3tA:
15.76
3ko0F-4u3tA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 11 SER A 368
ILE A 413
PHE A 420
ASP A 346
SER A 363
 None
 1.25A 3ko0E-4u3tA:
undetectable
3ko0F-4u3tA:
undetectable
3ko0G-4u3tA:
undetectable
3ko0H-4u3tA:
undetectable		 3ko0E-4u3tA:
15.76
3ko0F-4u3tA:
15.76
3ko0G-4u3tA:
15.76
3ko0H-4u3tA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 12 SER A 368
ILE A 413
PHE A 420
ASP A 346
SER A 363
 None
 1.21A 3ko0G-4u3tA:
undetectable
3ko0H-4u3tA:
undetectable
3ko0I-4u3tA:
undetectable
3ko0J-4u3tA:
undetectable		 3ko0G-4u3tA:
15.76
3ko0H-4u3tA:
15.76
3ko0I-4u3tA:
15.76
3ko0J-4u3tA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 12 ASP A 346
SER A 363
PHE A 420
SER A 368
ILE A 413
 None
 1.17A 3ko0G-4u3tA:
undetectable
3ko0H-4u3tA:
undetectable
3ko0I-4u3tA:
undetectable
3ko0J-4u3tA:
undetectable		 3ko0G-4u3tA:
15.76
3ko0H-4u3tA:
15.76
3ko0I-4u3tA:
15.76
3ko0J-4u3tA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 11 ASP A 346
SER A 363
PHE A 420
SER A 368
ILE A 413
 None
 1.25A 3ko0A-4u3tA:
undetectable
3ko0B-4u3tA:
undetectable
3ko0I-4u3tA:
undetectable
3ko0J-4u3tA:
undetectable		 3ko0A-4u3tA:
15.76
3ko0B-4u3tA:
15.76
3ko0I-4u3tA:
15.76
3ko0J-4u3tA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 12 SER A 368
ILE A 413
ASP A 346
SER A 363
PHE A 420
 None
 1.19A 3ko0K-4u3tA:
undetectable
3ko0L-4u3tA:
undetectable
3ko0M-4u3tA:
undetectable
3ko0N-4u3tA:
undetectable		 3ko0K-4u3tA:
15.76
3ko0L-4u3tA:
15.76
3ko0M-4u3tA:
15.76
3ko0N-4u3tA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN202_1
(PROTEIN S100-A4)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 11 ASP A 346
SER A 363
PHE A 420
SER A 368
ILE A 413
 None
 1.20A 3ko0K-4u3tA:
undetectable
3ko0L-4u3tA:
undetectable
3ko0M-4u3tA:
undetectable
3ko0N-4u3tA:
undetectable		 3ko0K-4u3tA:
15.76
3ko0L-4u3tA:
15.76
3ko0M-4u3tA:
15.76
3ko0N-4u3tA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 11 SER A 368
ILE A 413
PHE A 420
ASP A 346
SER A 363
 None
 1.15A 3ko0O-4u3tA:
undetectable
3ko0P-4u3tA:
undetectable
3ko0Q-4u3tA:
undetectable
3ko0R-4u3tA:
undetectable		 3ko0O-4u3tA:
15.76
3ko0P-4u3tA:
15.76
3ko0Q-4u3tA:
15.76
3ko0R-4u3tA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ202_1
(PROTEIN S100-A4)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 10 PHE A 420
ASP A 346
SER A 363
SER A 368
ILE A 413
 None
 1.15A 3ko0O-4u3tA:
undetectable
3ko0P-4u3tA:
undetectable
3ko0Q-4u3tA:
undetectable
3ko0R-4u3tA:
undetectable		 3ko0O-4u3tA:
15.76
3ko0P-4u3tA:
15.76
3ko0Q-4u3tA:
15.76
3ko0R-4u3tA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR202_1
(PROTEIN S100-A4)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 11 SER A 368
ILE A 413
ASP A 346
SER A 363
PHE A 420
 None
 1.19A 3ko0Q-4u3tA:
0.0
3ko0R-4u3tA:
0.0
3ko0S-4u3tA:
0.0
3ko0T-4u3tA:
undetectable		 3ko0Q-4u3tA:
15.76
3ko0R-4u3tA:
15.76
3ko0S-4u3tA:
15.76
3ko0T-4u3tA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT202_1
(PROTEIN S100-A4)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 11 ASP A 346
SER A 363
PHE A 420
SER A 368
ILE A 413
 None
 1.15A 3ko0Q-4u3tA:
undetectable
3ko0R-4u3tA:
undetectable
3ko0S-4u3tA:
undetectable
3ko0T-4u3tA:
undetectable		 3ko0Q-4u3tA:
15.76
3ko0R-4u3tA:
15.76
3ko0S-4u3tA:
15.76
3ko0T-4u3tA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_C_P77C203_1
(PROTEIN S100-A4)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 10 ASP A 346
SER A 363
PHE A 420
SER A 368
ILE A 413
 None
 1.23A 3m0wC-4u3tA:
undetectable
3m0wD-4u3tA:
undetectable
3m0wE-4u3tA:
undetectable
3m0wF-4u3tA:
undetectable		 3m0wC-4u3tA:
15.96
3m0wD-4u3tA:
15.96
3m0wE-4u3tA:
15.96
3m0wF-4u3tA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_I_P77I203_1
(PROTEIN S100-A4)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 10 SER A 368
ILE A 413
ASP A 346
SER A 363
PHE A 420
 None
 1.21A 3m0wA-4u3tA:
undetectable
3m0wB-4u3tA:
undetectable
3m0wI-4u3tA:
undetectable
3m0wJ-4u3tA:
undetectable		 3m0wA-4u3tA:
15.96
3m0wB-4u3tA:
15.96
3m0wI-4u3tA:
15.96
3m0wJ-4u3tA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 12 LEU A 431
THR A 534
ALA A 532
ILE A 530
ILE A 519
 None
 0.87A 3ut5B-4u3tA:
undetectable		 3ut5B-4u3tA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 12 PHE A 315
SER A 419
ILE A 317
ALA A 318
VAL A 470
 None
 1.08A 4dx5B-4u3tA:
undetectable		 4dx5B-4u3tA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 12 VAL A 266
LEU A 278
LEU A 268
VAL A 302
LEU A 431
 None
 1.22A 4m11C-4u3tA:
undetectable		 4m11C-4u3tA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_D_MXMD606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 12 VAL A 266
LEU A 278
LEU A 268
VAL A 302
LEU A 431
 None
 1.23A 4m11D-4u3tA:
undetectable		 4m11D-4u3tA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		4 / 5 TYR A 435
THR A 281
LEU A 251
MET A 557
 None
 1.44A 4mbsB-4u3tA:
undetectable		 4mbsB-4u3tA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		3 / 3 ASP A 346
LYS A 361
LEU A 353
 None
 0.99A 4ptjA-4u3tA:
undetectable		 4ptjA-4u3tA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 12 PHE A 315
SER A 419
ILE A 317
ALA A 318
PHE A 462
 None
 1.07A 4u8vB-4u3tA:
undetectable		 4u8vB-4u3tA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 12 PHE A 315
SER A 419
ILE A 317
ALA A 318
VAL A 470
 None
 1.07A 4u8vB-4u3tA:
undetectable		 4u8vB-4u3tA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 12 PHE A 315
SER A 419
ILE A 317
ALA A 318
PHE A 462
 None
 1.07A 4u8yB-4u3tA:
undetectable		 4u8yB-4u3tA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 12 PHE A 315
SER A 419
ILE A 317
ALA A 318
VAL A 470
 None
 1.12A 4u8yB-4u3tA:
undetectable		 4u8yB-4u3tA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 12 PHE A 315
SER A 419
ILE A 317
ALA A 318
VAL A 470
 None
 1.12A 4u95B-4u3tA:
undetectable		 4u95B-4u3tA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_B_QDNB602_1
(CYTOCHROME P450 2D6)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 9 PHE A 462
GLU A 385
ALA A 323
ASP A 322
ALA A 318
 None
 1.31A 4wnuB-4u3tA:
undetectable		 4wnuB-4u3tA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_D_QDND602_1
(CYTOCHROME P450 2D6)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 10 PHE A 462
GLU A 385
ALA A 323
ASP A 322
ALA A 318
 None
 1.35A 4wnuD-4u3tA:
undetectable		 4wnuD-4u3tA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 12 LEU A 386
ALA A 434
LEU A 438
ALA A 318
VAL A 316
 None
 1.15A 4x1iB-4u3tA:
undetectable		 4x1iB-4u3tA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		4 / 6 TYR A 422
PRO A 308
TYR A 383
LEU A 424
 None
 1.29A 5bmvB-4u3tA:
undetectable		 5bmvB-4u3tA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 12 LEU A 447
THR A 534
ALA A 532
ILE A 530
ILE A 519
 None
 0.86A 5itzB-4u3tA:
undetectable		 5itzB-4u3tA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 12 LEU A 431
THR A 534
ALA A 532
ILE A 530
ILE A 519
 None
 0.91A 5mioB-4u3tA:
undetectable		 5mioB-4u3tA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		4 / 8 ALA A 432
THR A 436
THR A 439
ALA A 455
 None
 0.94A 5x2tI-4u3tA:
undetectable
5x2tJ-4u3tA:
undetectable
5x2tK-4u3tA:
undetectable
5x2tL-4u3tA:
undetectable		 5x2tI-4u3tA:
17.58
5x2tJ-4u3tA:
20.73
5x2tK-4u3tA:
17.58
5x2tL-4u3tA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 12 LEU A 431
THR A 534
ALA A 532
ILE A 530
ILE A 519
 None
 0.90A 5xiwB-4u3tA:
undetectable		 5xiwB-4u3tA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 12 LEU A 447
THR A 534
ALA A 532
ILE A 530
ILE A 519
 None
 0.85A 5xiwB-4u3tA:
undetectable		 5xiwB-4u3tA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_2
(TUBULIN BETA CHAIN)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		5 / 12 LEU A 386
ALA A 434
LEU A 438
ALA A 318
LYS A 319
 None
 1.25A 5xiwD-4u3tA:
undetectable		 5xiwD-4u3tA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_D_EY4D500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4u3t PENICILLIN-BINDING
PROTEIN 2
(Neisseria
gonorrhoeae) 		4 / 7 ILE A 388
PRO A 308
ALA A 437
THR A 436
 None
 0.94A 6cduC-4u3tA:
undetectable
6cduD-4u3tA:
undetectable		 6cduC-4u3tA:
21.30
6cduD-4u3tA:
21.30