SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4u48'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 12 LEU A 754
LEU A 767
LEU A 802
GLN A 791
LEU A 842
 None
 1.37A 1a28B-4u48A:
undetectable		 1a28B-4u48A:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_1
(DIHYDROFOLATE
REDUCTASE)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 12 ILE A 609
LEU A 696
VAL A 654
LEU A 657
ILE A 642
 None
 1.01A 1df7A-4u48A:
undetectable		 1df7A-4u48A:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4003_1
(SERUM ALBUMIN)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 9 ILE A 884
VAL A 871
GLY A 975
ALA A 873
LEU A 853
 None
 0.94A 1e7bA-4u48A:
undetectable		 1e7bA-4u48A:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 8 ALA A 224
PHE A 192
VAL A 194
VAL A 261
 None
 0.46A 1epbB-4u48A:
undetectable		 1epbB-4u48A:
7.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 12 GLY A1178
CYH A1179
LEU A1537
MET A1625
TYR A1248
 None
 1.47A 1fm6D-4u48A:
undetectable		 1fm6D-4u48A:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 4 GLY A 925
ASP A 922
GLY A 285
THR A 280
 None
 0.85A 1hxbB-4u48A:
undetectable		 1hxbB-4u48A:
5.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 7 VAL A1071
THR A1039
LEU A1038
VAL A1035
 None
 0.90A 1jgsA-4u48A:
undetectable		 1jgsA-4u48A:
6.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 7 LEU A 585
LEU A 555
TYR A 504
LEU A 481
 None
 1.01A 1kt3A-4u48A:
undetectable		 1kt3A-4u48A:
8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 6 GLY A1545
THR A1611
PRO A1612
SER A1029
 None
 0.96A 1n4fA-4u48A:
undetectable		 1n4fA-4u48A:
5.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 12 GLY A1178
CYH A1179
LEU A1537
MET A1625
TYR A1248
 None
 1.49A 1zgyA-4u48A:
undetectable		 1zgyA-4u48A:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 11 LEU A1414
LEU A1377
LEU A1404
LEU A1422
ARG A1167
 None
 1.02A 2ceoA-4u48A:
undetectable		 2ceoA-4u48A:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 12 LEU A 802
LEU A 767
LEU A 754
ILE A 793
VAL A 750
 None
 1.10A 2pnjA-4u48A:
undetectable		 2pnjA-4u48A:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 12 SER A 818
HIS A 289
TYR A 778
VAL A 795
LEU A 363
 None
 1.33A 2prgB-4u48A:
undetectable		 2prgB-4u48A:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 7 LEU A1316
ALA A1341
LEU A1338
ALA A1354
 None
 0.89A 2vcvG-4u48A:
undetectable		 2vcvG-4u48A:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 8 LEU A1316
ALA A1341
LEU A1338
ALA A1354
 None
 0.80A 2vcvP-4u48A:
1.6		 2vcvP-4u48A:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 6 THR A1611
GLU A1547
PHE A1022
ILE A1113
 None
 0.98A 2w98B-4u48A:
undetectable		 2w98B-4u48A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_B_CL9B401_2
(DEOXYCYTIDINE KINASE)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 4 ARG A1478
ASP A1480
LEU A1414
ARG A1429
 None
 1.39A 2ziaB-4u48A:
undetectable		 2ziaB-4u48A:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 12 LEU A 767
THR A 803
GLN A 791
ALA A 779
THR A 819
 None
 1.12A 3a35A-4u48A:
2.1		 3a35A-4u48A:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 12 LEU A 767
THR A 803
GLN A 791
ALA A 779
THR A 819
 None
 1.13A 3a3bA-4u48A:
undetectable		 3a3bA-4u48A:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 6 GLN A1311
GLY A1257
ARG A1255
LEU A1191
 None
 1.06A 3bjwE-4u48A:
undetectable		 3bjwE-4u48A:
4.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 12 THR A 359
LEU A 344
THR A 353
VAL A 259
THR A 280
 None
 1.05A 3czhB-4u48A:
undetectable		 3czhB-4u48A:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 4 GLY A 656
VAL A 654
GLY A 702
THR A 701
 None
 0.73A 3ib2A-4u48A:
undetectable		 3ib2A-4u48A:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		3 / 3 ARG A1367
ASP A1379
ASP A1365
 None
 0.92A 3jb2A-4u48A:
undetectable		 3jb2A-4u48A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		3 / 3 ARG A1367
ASP A1379
ASP A1365
 None
 0.83A 3jb3A-4u48A:
undetectable		 3jb3A-4u48A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 4 GLY A 925
ASP A 922
GLY A 285
THR A 280
 None
 0.92A 3k4vC-4u48A:
undetectable		 3k4vC-4u48A:
4.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 12 LEU A1038
GLY A 982
ALA A1010
LEU A 988
ILE A 981
 None
 0.97A 3ku1A-4u48A:
undetectable		 3ku1A-4u48A:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		6 / 12 LEU A1038
VAL A 957
GLY A 982
ALA A1010
LEU A 988
ILE A 981
 None
 1.01A 3ku1H-4u48A:
undetectable		 3ku1H-4u48A:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		3 / 3 ARG A1021
PRO A1543
PHE A1022
 None
 1.04A 3thrC-4u48A:
2.1		 3thrC-4u48A:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		3 / 3 LEU A1357
MET A1336
ASP A1379
 None
 0.68A 3v5wA-4u48A:
undetectable		 3v5wA-4u48A:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 12 LEU A1245
LEU A1382
ALA A1299
ALA A1302
TYR A1303
 None
 1.13A 3vw7A-4u48A:
undetectable		 3vw7A-4u48A:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		3 / 3 ASP A 892
GLU A 987
GLY A 986
 None
 0.60A 3w9tA-4u48A:
undetectable		 3w9tA-4u48A:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZMD_A_SALA201_1
(PUTATIVE
TRANSCRIPTIONAL
REGULATOR)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 8 TRP A 995
LEU A 437
ARG A 439
GLU A 434
 None
 1.50A 3zmdA-4u48A:
undetectable
3zmdB-4u48A:
undetectable		 3zmdA-4u48A:
8.38
3zmdB-4u48A:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 7 ARG A1030
GLY A1613
VAL A1642
SER A1517
 None
 0.94A 4a3uB-4u48A:
undetectable		 4a3uB-4u48A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BWL_C_MN9C1297_0
(N-ACETYLNEURAMINATE
LYASE)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 10 ILE A 251
LEU A 254
THR A 229
GLY A 230
PHE A 279
 None
 1.25A 4bwlC-4u48A:
undetectable		 4bwlC-4u48A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 12 LEU A 802
LEU A 767
LEU A 754
ILE A 793
VAL A 750
 None
 1.12A 4f4dB-4u48A:
undetectable		 4f4dB-4u48A:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 12 VAL A1013
ILE A1047
VAL A1065
LEU A1045
LEU A1075
 None
 1.05A 4m11B-4u48A:
undetectable		 4m11B-4u48A:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 6 THR A 459
LEU A 397
LEU A 437
GLU A 434
 None
 1.28A 4nc3A-4u48A:
undetectable		 4nc3A-4u48A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 11 ARG A 117
LEU A 109
ALA A 110
VAL A  92
LEU A  59
 None
 1.16A 4nqaA-4u48A:
undetectable		 4nqaA-4u48A:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 12 TYR A1615
ALA A1081
GLY A1025
ILE A1113
GLY A1088
 None
 1.31A 4obwD-4u48A:
undetectable		 4obwD-4u48A:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA602_1
(SERUM ALBUMIN)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 9 ALA A1421
ALA A1425
LEU A1386
SER A1376
LEU A1377
 None
 1.37A 4or0A-4u48A:
2.7		 4or0A-4u48A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 6 ARG A1363
ALA A1330
ASP A1379
SER A1290
 None
 0.99A 4ot2A-4u48A:
2.7		 4ot2A-4u48A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 12 GLY A1518
ALA A1609
VAL A1642
TYR A1615
ASN A1018
 None
 1.14A 4pd5A-4u48A:
undetectable		 4pd5A-4u48A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 12 GLY A1518
ALA A1609
VAL A1642
TYR A1615
ASN A1018
 None
 1.14A 4pd9A-4u48A:
undetectable		 4pd9A-4u48A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 6 LEU A 842
THR A 819
LEU A 815
SER A 783
 None
 0.94A 4pwjA-4u48A:
3.5		 4pwjA-4u48A:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 6 LEU A 853
THR A 626
LEU A 855
SER A1005
 None
 0.99A 4pwjA-4u48A:
3.5		 4pwjA-4u48A:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_B_15UB301_1
(THROMBIN HEAVY CHAIN)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 12 LEU A 853
ALA A 994
VAL A 886
GLY A 973
GLY A 975
 None
 1.02A 4rn6B-4u48A:
undetectable		 4rn6B-4u48A:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 12 SER A1624
SER A1375
GLU A1418
ILE A1370
ALA A1330
 None
 1.08A 4u95B-4u48A:
undetectable		 4u95B-4u48A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 12 LEU A 853
LEU A 969
VAL A 888
ALA A 992
ILE A 967
 None
 0.99A 4x1yD-4u48A:
undetectable		 4x1yD-4u48A:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 8 ARG A 402
ASP A 998
ASP A 405
ASP A 403
 None
 0.98A 4xqgA-4u48A:
undetectable		 4xqgA-4u48A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 8 ARG A 402
ASP A 998
ASP A 405
ASP A 403
 None
 0.98A 4xqgB-4u48A:
undetectable		 4xqgB-4u48A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 7 SER A1415
ARG A1363
SER A1375
GLU A1418
 None
 1.30A 4xzkA-4u48A:
undetectable		 4xzkA-4u48A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		3 / 3 ALA A 645
TYR A 644
PRO A 602
 None
 0.69A 4zdyA-4u48A:
undetectable		 4zdyA-4u48A:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		3 / 3 ALA A 779
TYR A 778
PRO A 787
 None
 0.58A 4zdyA-4u48A:
undetectable		 4zdyA-4u48A:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		3 / 3 ARG A1585
TYR A1581
GLU A1583
 None
 0.66A 4zzbE-4u48A:
3.3		 4zzbE-4u48A:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		3 / 3 VAL A 976
THR A 868
ARG A 870
 None
 0.76A 5b2sB-4u48A:
1.7		 5b2sB-4u48A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		3 / 3 VAL A 976
THR A 868
ARG A 870
 None
 0.78A 5b2tB-4u48A:
0.8		 5b2tB-4u48A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ENT_C_MIYC901_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 9 SER A1624
SER A1375
GLU A1418
ILE A1370
ALA A1330
 None
 1.12A 5entC-4u48A:
undetectable		 5entC-4u48A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		3 / 3 VAL A 179
HIS A 186
VAL A 184
 None
 0.64A 5jmnC-4u48A:
undetectable		 5jmnC-4u48A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_1
(PROTEASE E35D-DRV)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 12 VAL A 795
ILE A 769
GLY A 838
PRO A 772
VAL A 773
 None
 0.98A 5kqyA-4u48A:
undetectable		 5kqyA-4u48A:
4.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		3 / 3 TRP A1111
MET A1019
ASN A1018
 None
 1.34A 5uc1B-4u48A:
undetectable		 5uc1B-4u48A:
3.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		6 / 12 GLU A1389
LEU A1377
LEU A1422
ALA A1425
SER A1428
ARG A1363
 None
 1.49A 6b0cD-4u48A:
undetectable		 6b0cD-4u48A:
4.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		4 / 8 TYR A1626
THR A1183
TYR A1248
LEU A1172
 None
 1.24A 6cnjD-4u48A:
undetectable
6cnjE-4u48A:
2.9		 6cnjD-4u48A:
4.13
6cnjE-4u48A:
3.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_1
(PROTEASE)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 12 VAL A 795
GLY A 838
LEU A 800
PRO A 772
VAL A 773
 None
 0.91A 6dgxB-4u48A:
undetectable		 6dgxB-4u48A:
4.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		5 / 10 VAL A 795
ILE A 769
GLY A 838
PRO A 772
VAL A 773
 None
 1.01A 6dj2A-4u48A:
undetectable		 6dj2A-4u48A:
4.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN
(Salmonella
enterica) 		3 / 3 ARG A1608
GLY A1518
GLU A1519
 None
 0.63A 6fgdA-4u48A:
undetectable		 6fgdA-4u48A:
12.99