SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4u5w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 4u5w TYROSINE-PROTEIN
KINASE HCK
(Homo
sapiens) 		4 / 8 ASP B 176
PHE B 149
LEU B 223
GLY B 182
 None
 1.02A 1rmtC-4u5wB:
undetectable		 1rmtC-4u5wB:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 4u5w TYROSINE-PROTEIN
KINASE HCK
(Homo
sapiens) 		4 / 4 ARG B 194
ASP B 190
ASP B 192
PRO B 193
 None
 1.33A 3fgrB-4u5wB:
undetectable		 3fgrB-4u5wB:
19.78