SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4u5x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JNO_A_DVAA6_0 (GRAMICIDIN A)	4u5x	RAC-LIKE GTP-BINDING PROTEIN 1 (Oryza sativa)	3 / 3	ALA A 66 VAL A 16 TRP A 104	GNP A 201 ( 4.5A) None None	0.86A	1jnoA-4u5xA: undetectable	1jnoA-4u5xA: 12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JNO_B_DVAB6_0 (GRAMICIDIN A)	4u5x	RAC-LIKE GTP-BINDING PROTEIN 1 (Oryza sativa)	3 / 3	ALA A 66 VAL A 16 TRP A 104	GNP A 201 ( 4.5A) None None	0.86A	1jnoB-4u5xA: undetectable	1jnoB-4u5xA: 12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MAG_A_DVAA6_0 (GRAMICIDIN A)	4u5x	RAC-LIKE GTP-BINDING PROTEIN 1 (Oryza sativa)	3 / 3	ALA A 66 VAL A 16 TRP A 104	GNP A 201 ( 4.5A) None None	0.90A	1magA-4u5xA: undetectable	1magA-4u5xA: 12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MAG_B_DVAB6_0 (GRAMICIDIN A)	4u5x	RAC-LIKE GTP-BINDING PROTEIN 1 (Oryza sativa)	3 / 3	ALA A 66 VAL A 16 TRP A 104	GNP A 201 ( 4.5A) None None	0.90A	1magB-4u5xA: undetectable	1magB-4u5xA: 12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NG8_A_DVAA6_0 (GRAMICIDIN A)	4u5x	RAC-LIKE GTP-BINDING PROTEIN 1 (Oryza sativa)	3 / 3	ALA A 66 VAL A 16 TRP A 104	GNP A 201 ( 4.5A) None None	0.86A	1ng8A-4u5xA: undetectable	1ng8A-4u5xA: 16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NG8_B_DVAB6_0 (GRAMICIDIN A)	4u5x	RAC-LIKE GTP-BINDING PROTEIN 1 (Oryza sativa)	3 / 3	ALA A 66 VAL A 16 TRP A 104	GNP A 201 ( 4.5A) None None	0.86A	1ng8B-4u5xA: undetectable	1ng8B-4u5xA: 16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NRU_A_DVAA6_0 (GRAMICIDIN A)	4u5x	RAC-LIKE GTP-BINDING PROTEIN 1 (Oryza sativa)	3 / 3	ALA A 66 VAL A 16 TRP A 104	GNP A 201 ( 4.5A) None None	0.89A	1nruA-4u5xA: undetectable	1nruA-4u5xA: 12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NRU_B_DVAB6_0 (GRAMICIDIN A)	4u5x	RAC-LIKE GTP-BINDING PROTEIN 1 (Oryza sativa)	3 / 3	ALA A 66 VAL A 16 TRP A 104	GNP A 201 ( 4.5A) None None	0.89A	1nruB-4u5xA: undetectable	1nruB-4u5xA: 12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EL0_A_1UNA201_1 (PROTEASE)	4u5x	RAC-LIKE GTP-BINDING PROTEIN 1 (Oryza sativa)	4 / 8	GLY A 81 ALA A 82 ASP A 83 THR A 65	None None GOL A 204 (-3.4A) None	0.60A	3el0A-4u5xA: undetectable	3el0A-4u5xA: 20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K4V_D_ROCD201_2 (HIV-1 PROTEASE)	4u5x	RAC-LIKE GTP-BINDING PROTEIN 1 (Oryza sativa)	4 / 4	GLY A 81 ASP A 83 GLY A 61 THR A 65	None GOL A 204 (-3.4A) None None	0.90A	3k4vC-4u5xA: undetectable	3k4vC-4u5xA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BPY_A_ACTA408_0 (THIOREDOXIN REDUCTASE)	4u5x	RAC-LIKE GTP-BINDING PROTEIN 1 (Oryza sativa)	3 / 3	PRO A 137 SER A 139 SER A 140	None	0.60A	6bpyA-4u5xA: undetectable	6bpyA-4u5xA: 19.20

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1JNO_A_DVAA6_0","GRAMICIDIN A","4u5x","RAC-LIKE GTP-BINDING PROTEIN 1","Oryza sativa",3,"ALA A  66;VAL A  16;TRP A 104","GNP A 201 ( 4.5A);None;None","0.86A","1jnoA-4u5xA:undetectable","1jnoA-4u5xA:12.22"],["1JNO_B_DVAB6_0","GRAMICIDIN A","4u5x","RAC-LIKE GTP-BINDING PROTEIN 1","Oryza sativa",3,"ALA A  66;VAL A  16;TRP A 104","GNP A 201 ( 4.5A);None;None","0.86A","1jnoB-4u5xA:undetectable","1jnoB-4u5xA:12.22"],["1MAG_A_DVAA6_0","GRAMICIDIN A","4u5x","RAC-LIKE GTP-BINDING PROTEIN 1","Oryza sativa",3,"ALA A  66;VAL A  16;TRP A 104","GNP A 201 ( 4.5A);None;None","0.90A","1magA-4u5xA:undetectable","1magA-4u5xA:12.22"],["1MAG_B_DVAB6_0","GRAMICIDIN A","4u5x","RAC-LIKE GTP-BINDING PROTEIN 1","Oryza sativa",3,"ALA A  66;VAL A  16;TRP A 104","GNP A 201 ( 4.5A);None;None","0.90A","1magB-4u5xA:undetectable","1magB-4u5xA:12.22"],["1NG8_A_DVAA6_0","GRAMICIDIN A","4u5x","RAC-LIKE GTP-BINDING PROTEIN 1","Oryza sativa",3,"ALA A  66;VAL A  16;TRP A 104","GNP A 201 ( 4.5A);None;None","0.86A","1ng8A-4u5xA:undetectable","1ng8A-4u5xA:16.42"],["1NG8_B_DVAB6_0","GRAMICIDIN A","4u5x","RAC-LIKE GTP-BINDING PROTEIN 1","Oryza sativa",3,"ALA A  66;VAL A  16;TRP A 104","GNP A 201 ( 4.5A);None;None","0.86A","1ng8B-4u5xA:undetectable","1ng8B-4u5xA:16.42"],["1NRU_A_DVAA6_0","GRAMICIDIN A","4u5x","RAC-LIKE GTP-BINDING PROTEIN 1","Oryza sativa",3,"ALA A  66;VAL A  16;TRP A 104","GNP A 201 ( 4.5A);None;None","0.89A","1nruA-4u5xA:undetectable","1nruA-4u5xA:12.22"],["1NRU_B_DVAB6_0","GRAMICIDIN A","4u5x","RAC-LIKE GTP-BINDING PROTEIN 1","Oryza sativa",3,"ALA A  66;VAL A  16;TRP A 104","GNP A 201 ( 4.5A);None;None","0.89A","1nruB-4u5xA:undetectable","1nruB-4u5xA:12.22"],["3EL0_A_1UNA201_1","PROTEASE","4u5x","RAC-LIKE GTP-BINDING PROTEIN 1","Oryza sativa",4,"GLY A  81;ALA A  82;ASP A  83;THR A  65","None;None;GOL A 204 (-3.4A);None","0.60A","3el0A-4u5xA:undetectable","3el0A-4u5xA:20.11"],["3K4V_D_ROCD201_2","HIV-1 PROTEASE;HIV-1 PROTEASE","4u5x","RAC-LIKE GTP-BINDING PROTEIN 1","Oryza sativa",4,"GLY A  81;ASP A  83;GLY A  61;THR A  65","None;GOL A 204 (-3.4A);None;None","0.90A","3k4vC-4u5xA:undetectable","3k4vC-4u5xA:20.00"],["6BPY_A_ACTA408_0","THIOREDOXIN REDUCTASE","4u5x","RAC-LIKE GTP-BINDING PROTEIN 1","Oryza sativa",3,"PRO A 137;SER A 139;SER A 140","None","0.60A","6bpyA-4u5xA:undetectable","6bpyA-4u5xA:19.20"]]