SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4u88'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YI4_A_ADNA306_1
(PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 4u88 TRANSCRIPTIONAL
REGULATOR SAER
(Staphylococcus
aureus) 		5 / 10 LEU A  90
ALA A 118
ILE A 167
LEU A 117
ILE A 153
 None
 1.10A 1yi4A-4u88A:
undetectable		 1yi4A-4u88A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 4u88 TRANSCRIPTIONAL
REGULATOR SAER
(Staphylococcus
aureus) 		3 / 3 MET A 106
GLU A 110
LEU A 114
 None
 0.77A 4v2oB-4u88A:
undetectable		 4v2oB-4u88A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 4u88 TRANSCRIPTIONAL
REGULATOR SAER
(Staphylococcus
aureus) 		5 / 11 VAL A  99
VAL A 104
VAL A  97
ILE A 167
ILE A 153
 None
 1.07A 5e4dB-4u88A:
undetectable		 5e4dB-4u88A:
19.79