SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4u8f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 4u8f PUTATIVE
UNCHARACTERIZED
PROTEIN GBS1892
(Streptococcus
agalactiae) 		5 / 12 ILE A   3
LEU A  59
LEU A  60
LEU A   5
ILE A   6
 None
 1.19A 1fmlB-4u8fA:
undetectable		 1fmlB-4u8fA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		 4u8f PUTATIVE
UNCHARACTERIZED
PROTEIN GBS1892
(Streptococcus
agalactiae) 		5 / 12 LEU A 134
PHE A 135
ALA A   4
ILE A   3
ALA A 110
 None
 1.15A 2bxpA-4u8fA:
undetectable		 2bxpA-4u8fA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 4u8f PUTATIVE
UNCHARACTERIZED
PROTEIN GBS1892
(Streptococcus
agalactiae) 		5 / 9 VAL A  89
GLY A  87
GLN A 152
ASN A 109
GLY A 108
 None
 1.42A 3kmoA-4u8fA:
undetectable		 3kmoA-4u8fA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4u8f PUTATIVE
UNCHARACTERIZED
PROTEIN GBS1892
(Streptococcus
agalactiae) 		6 / 12 ALA A   4
ALA A 196
THR A 184
ILE A 185
LEU A 207
ILE A  58
 None
 1.37A 4kjjA-4u8fA:
undetectable		 4kjjA-4u8fA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4u8f PUTATIVE
UNCHARACTERIZED
PROTEIN GBS1892
(Streptococcus
agalactiae) 		4 / 6 GLU A  43
GLU A  44
TYR A  39
GLU A 188
 None
 1.38A 4mi4A-4u8fA:
undetectable		 4mi4A-4u8fA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSS_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4u8f PUTATIVE
UNCHARACTERIZED
PROTEIN GBS1892
(Streptococcus
agalactiae) 		6 / 12 ALA A   4
ALA A 196
THR A 184
ILE A 185
LEU A 207
ILE A  58
 None
 1.37A 4pssA-4u8fA:
undetectable		 4pssA-4u8fA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 4u8f PUTATIVE
UNCHARACTERIZED
PROTEIN GBS1892
(Streptococcus
agalactiae) 		5 / 12 ILE A   6
LEU A  59
SER A  45
GLY A  37
GLY A 187
 None
 1.10A 5nnaD-4u8fA:
undetectable		 5nnaD-4u8fA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UH6_C_RFPC1201_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 4u8f PUTATIVE
UNCHARACTERIZED
PROTEIN GBS1892
(Streptococcus
agalactiae) 		5 / 12 GLN A  46
LEU A  47
GLN A  51
ASP A 177
SER A 186
 None
 1.37A 5uh6C-4u8fA:
undetectable		 5uh6C-4u8fA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4u8f PUTATIVE
UNCHARACTERIZED
PROTEIN GBS1892
(Streptococcus
agalactiae) 		4 / 5 ILE A  58
LEU A  59
THR A  48
LEU A  47
 None
 0.77A 6nmpN-4u8fA:
undetectable
6nmpW-4u8fA:
undetectable		 6nmpN-4u8fA:
15.72
6nmpW-4u8fA:
13.64