SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4u8t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		4 / 8 SER A 194
ASN A 197
ILE A 199
GLU A 189
 None
 0.94A 1meiA-4u8tA:
undetectable		 1meiA-4u8tA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		5 / 12 CYH A 236
PHE A 235
LEU A 188
ASP A 297
SER A 202
 None
None
None
C  O   1 ( 4.8A)
None
 1.22A 3ko0A-4u8tA:
undetectable
3ko0B-4u8tA:
undetectable
3ko0C-4u8tA:
undetectable
3ko0D-4u8tA:
undetectable		 3ko0A-4u8tA:
19.21
3ko0B-4u8tA:
19.21
3ko0C-4u8tA:
19.21
3ko0D-4u8tA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD201_1
(PROTEIN S100-A4)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		4 / 8 GLY A 198
CYH A 236
PHE A 235
PHE A 313
 None
 0.99A 3ko0D-4u8tA:
undetectable
3ko0E-4u8tA:
undetectable		 3ko0D-4u8tA:
19.21
3ko0E-4u8tA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		5 / 12 ASP A 297
SER A 202
CYH A 236
PHE A 235
LEU A 188
 C  O   1 ( 4.8A)
None
None
None
None
 1.20A 3ko0G-4u8tA:
undetectable
3ko0H-4u8tA:
undetectable
3ko0I-4u8tA:
undetectable
3ko0J-4u8tA:
undetectable		 3ko0G-4u8tA:
19.21
3ko0H-4u8tA:
19.21
3ko0I-4u8tA:
19.21
3ko0J-4u8tA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ201_1
(PROTEIN S100-A4)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		4 / 8 GLY A 198
CYH A 236
PHE A 235
PHE A 313
 None
 1.00A 3ko0B-4u8tA:
undetectable
3ko0J-4u8tA:
undetectable		 3ko0B-4u8tA:
19.21
3ko0J-4u8tA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		4 / 7 GLY A 198
CYH A 236
PHE A 235
PHE A 313
 None
 0.99A 3ko0L-4u8tA:
undetectable
3ko0N-4u8tA:
undetectable		 3ko0L-4u8tA:
19.21
3ko0N-4u8tA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		5 / 12 LEU A 188
CYH A 236
PHE A 235
ASP A 297
SER A 202
 None
None
None
C  O   1 ( 4.8A)
None
 1.22A 3ko0K-4u8tA:
undetectable
3ko0L-4u8tA:
undetectable
3ko0M-4u8tA:
undetectable
3ko0N-4u8tA:
undetectable		 3ko0K-4u8tA:
19.21
3ko0L-4u8tA:
19.21
3ko0M-4u8tA:
19.21
3ko0N-4u8tA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS201_1
(PROTEIN S100-A4)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		4 / 7 GLY A 198
CYH A 236
PHE A 235
PHE A 313
 None
 1.04A 3ko0K-4u8tA:
undetectable
3ko0S-4u8tA:
undetectable		 3ko0K-4u8tA:
19.21
3ko0S-4u8tA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_A_P77A203_1
(PROTEIN S100-A4)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		5 / 10 ASP A 297
SER A 202
LEU A 188
CYH A 236
PHE A 235
 C  O   1 ( 4.8A)
None
None
None
None
 1.15A 3m0wA-4u8tA:
undetectable
3m0wB-4u8tA:
undetectable
3m0wI-4u8tA:
undetectable
3m0wJ-4u8tA:
undetectable		 3m0wA-4u8tA:
20.12
3m0wB-4u8tA:
20.12
3m0wI-4u8tA:
20.12
3m0wJ-4u8tA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_D_P77D203_1
(PROTEIN S100-A4)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		5 / 10 CYH A 236
PHE A 235
LEU A 188
ASP A 297
SER A 202
 None
None
None
C  O   1 ( 4.8A)
None
 1.16A 3m0wA-4u8tA:
undetectable
3m0wB-4u8tA:
undetectable
3m0wC-4u8tA:
undetectable
3m0wD-4u8tA:
undetectable		 3m0wA-4u8tA:
20.12
3m0wB-4u8tA:
20.12
3m0wC-4u8tA:
20.12
3m0wD-4u8tA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		5 / 8 ASP A 297
SER A 202
CYH A 236
PHE A 235
LEU A 188
 C  O   1 ( 4.8A)
None
None
None
None
 1.17A 3m0wE-4u8tA:
undetectable
3m0wF-4u8tA:
undetectable
3m0wG-4u8tA:
undetectable
3m0wH-4u8tA:
undetectable		 3m0wE-4u8tA:
20.12
3m0wF-4u8tA:
20.12
3m0wG-4u8tA:
20.12
3m0wH-4u8tA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_F_P77F203_1
(PROTEIN S100-A4)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		5 / 9 LEU A 188
CYH A 236
PHE A 235
ASP A 297
SER A 202
 None
None
None
C  O   1 ( 4.8A)
None
 1.14A 3m0wC-4u8tA:
undetectable
3m0wD-4u8tA:
undetectable
3m0wE-4u8tA:
undetectable
3m0wF-4u8tA:
undetectable		 3m0wC-4u8tA:
20.12
3m0wD-4u8tA:
20.12
3m0wE-4u8tA:
20.12
3m0wF-4u8tA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_A_NOVA2000_1
(DNA GYRASE SUBUNIT B)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		5 / 12 ASN A 207
GLU A 212
GLN A 299
SER A 202
ARG A 179
 None
 1.34A 4uroA-4u8tA:
undetectable		 4uroA-4u8tA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_B_NOVB2000_1
(DNA GYRASE SUBUNIT B)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		5 / 12 ASN A 207
GLU A 212
GLN A 299
SER A 202
ARG A 179
 None
 1.29A 4uroB-4u8tA:
undetectable		 4uroB-4u8tA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		5 / 12 ASN A 207
GLU A 212
GLN A 299
SER A 202
ARG A 179
 None
 1.33A 4uroC-4u8tA:
undetectable		 4uroC-4u8tA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA303_1
(CHITOSANASE)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		4 / 5 ASP A 327
VAL A 271
GLY A 165
ALA A 166
 None
 1.01A 5hwaA-4u8tA:
undetectable		 5hwaA-4u8tA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		3 / 3 THR A 203
SER A 202
TYR A 260
 G  O  -1 ( 3.5A)
None
None
 0.81A 5jsdA-4u8tA:
undetectable		 5jsdA-4u8tA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		3 / 3 THR A 203
SER A 202
TYR A 260
 G  O  -1 ( 3.5A)
None
None
 0.82A 5jsdB-4u8tA:
undetectable		 5jsdB-4u8tA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		3 / 3 THR A 203
SER A 202
TYR A 260
 G  O  -1 ( 3.5A)
None
None
 0.81A 5jsdC-4u8tA:
undetectable		 5jsdC-4u8tA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		3 / 3 THR A 203
SER A 202
TYR A 260
 G  O  -1 ( 3.5A)
None
None
 0.83A 5jseA-4u8tA:
undetectable		 5jseA-4u8tA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		3 / 3 THR A 203
SER A 202
TYR A 260
 G  O  -1 ( 3.5A)
None
None
 0.83A 5jseB-4u8tA:
undetectable		 5jseB-4u8tA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		3 / 3 THR A 203
SER A 202
TYR A 260
 G  O  -1 ( 3.5A)
None
None
 0.83A 5jseC-4u8tA:
undetectable		 5jseC-4u8tA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IFT_A_SAMA301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)		 4u8t ZYRO0G01672P
(Zygosaccharomyce
s
rouxii) 		5 / 12 LEU A 225
ILE A 309
GLY A 237
ALA A 239
ASP A 273
 None
 1.05A 6iftA-4u8tA:
undetectable		 6iftA-4u8tA:
21.31