SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4u98'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 11 LEU A 406
ALA A 407
GLU A 410
HIS A 449
LEU A 447
 None
 1.13A 1g50A-4u98A:
undetectable		 1g50A-4u98A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_A_ESTA600_1
(OESTROGEN RECEPTOR)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 10 LEU A 406
ALA A 407
GLU A 410
HIS A 449
LEU A 447
 None
 1.01A 1gwrA-4u98A:
2.3		 1gwrA-4u98A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_B_ESTB600_1
(OESTROGEN RECEPTOR)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 9 LEU A 406
ALA A 407
GLU A 410
HIS A 449
LEU A 447
 None
 1.02A 1gwrB-4u98A:
undetectable		 1gwrB-4u98A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 11 ALA A 271
LEU A 278
ARG A 349
LEU A 411
SER A 435
 None
 1.14A 1h9zA-4u98A:
undetectable		 1h9zA-4u98A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		3 / 3 ALA A 385
VAL A 380
TRP A 379
 None
 0.75A 1kqeA-4u98A:
undetectable
1kqeE-4u98A:
undetectable		 1kqeA-4u98A:
1.87
1kqeE-4u98A:
1.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		3 / 3 ALA A 385
VAL A 380
TRP A 379
 None
 0.74A 1kqeB-4u98A:
undetectable
1kqeD-4u98A:
undetectable		 1kqeB-4u98A:
1.87
1kqeD-4u98A:
1.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		3 / 3 TRP A 379
ALA A 385
VAL A 380
 None
 0.76A 1kqeB-4u98A:
undetectable
1kqeD-4u98A:
undetectable		 1kqeB-4u98A:
1.87
1kqeD-4u98A:
1.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		3 / 3 TRP A 379
ALA A 385
VAL A 380
 None
 0.75A 1kqeA-4u98A:
undetectable
1kqeE-4u98A:
undetectable		 1kqeA-4u98A:
1.87
1kqeE-4u98A:
1.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		3 / 3 ALA A 385
VAL A 380
TRP A 379
 None
 0.90A 1micA-4u98A:
undetectable
1micB-4u98A:
undetectable		 1micA-4u98A:
2.31
1micB-4u98A:
2.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 12 LEU A 292
LEU A 447
GLY A 403
ASP A 402
ALA A 345
 None
 1.04A 2bm9F-4u98A:
undetectable		 2bm9F-4u98A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 12 LEU A 292
LEU A 447
GLY A 403
ASP A 402
ALA A 345
 None
 1.01A 2br4D-4u98A:
undetectable		 2br4D-4u98A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		4 / 5 PRO A 432
ALA A 414
ASP A 374
ASP A 437
 None
 1.19A 2nyuB-4u98A:
undetectable		 2nyuB-4u98A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		4 / 5 LEU A 278
ARG A 281
ALA A 272
ILE A 436
 None
 1.12A 2qhfA-4u98A:
undetectable		 2qhfA-4u98A:
26.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 12 LEU A 406
ALA A 407
GLU A 410
HIS A 449
LEU A 447
 None
 1.08A 3olsA-4u98A:
undetectable		 3olsA-4u98A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 12 LEU A 406
ALA A 407
GLU A 410
HIS A 449
LEU A 447
 None
 1.08A 3q95B-4u98A:
undetectable		 3q95B-4u98A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SM2_A_478A126_2
(GAG-PRO-POL
POLYPROTEIN)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 11 ASP A 343
HIS A 307
VAL A 347
VAL A 311
TYR A 391
 None
 1.01A 3sm2B-4u98A:
undetectable		 3sm2B-4u98A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		4 / 5 ARG A 400
LEU A 406
VAL A 344
ASP A 398
 None
 1.05A 3ufnA-4u98A:
undetectable
3ufnB-4u98A:
undetectable		 3ufnA-4u98A:
12.53
3ufnB-4u98A:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 11 GLY A 390
ALA A 240
GLY A 238
VAL A 394
HIS A 175
 None
 1.36A 4c5lA-4u98A:
undetectable		 4c5lA-4u98A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 9 GLY A 390
ALA A 240
GLY A 238
VAL A 394
HIS A 175
 None
 1.34A 4c5lB-4u98A:
undetectable		 4c5lB-4u98A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_C_UEGC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 10 GLY A 390
ALA A 240
GLY A 238
VAL A 394
HIS A 175
 None
 1.37A 4c5lC-4u98A:
undetectable		 4c5lC-4u98A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 10 GLY A 390
ALA A 240
GLY A 238
VAL A 394
HIS A 175
 None
 1.30A 4c5lD-4u98A:
undetectable		 4c5lD-4u98A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 10 GLY A 390
ALA A 240
GLY A 238
VAL A 394
HIS A 175
 None
 1.31A 4c5nB-4u98A:
undetectable		 4c5nB-4u98A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 10 GLY A 390
ALA A 240
GLY A 238
VAL A 394
HIS A 175
 None
 1.30A 4c5nD-4u98A:
undetectable		 4c5nD-4u98A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 12 LEU A 406
ALA A 407
GLU A 410
HIS A 449
LEU A 447
 None
 1.13A 4j24D-4u98A:
undetectable		 4j24D-4u98A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 12 LEU A 406
ALA A 407
GLU A 410
HIS A 449
LEU A 447
 None
 1.06A 4pxmA-4u98A:
undetectable		 4pxmA-4u98A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 11 LEU A 406
ALA A 407
GLU A 410
HIS A 449
LEU A 447
 None
 1.05A 4pxmB-4u98A:
undetectable		 4pxmB-4u98A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 12 ARG A 178
GLY A 172
ALA A 169
ALA A 120
GLN A 170
 None
 1.21A 4ryaA-4u98A:
undetectable		 4ryaA-4u98A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		4 / 6 LEU A 331
ASN A 159
PRO A 160
ARG A 342
 None
 1.21A 4yv5B-4u98A:
0.9		 4yv5B-4u98A:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		4 / 6 LEU A 331
ASN A 159
PRO A 160
ARG A 342
 None
 1.22A 4yv5A-4u98A:
undetectable		 4yv5A-4u98A:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		3 / 3 TYR A  46
THR A  47
THR A  50
 None
 0.83A 5aoxE-4u98A:
undetectable		 5aoxE-4u98A:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 10 LEU A 406
ALA A 407
GLU A 410
HIS A 449
LEU A 447
 None
 1.11A 5dx3A-4u98A:
undetectable		 5dx3A-4u98A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 11 LEU A 406
ALA A 407
GLU A 410
HIS A 449
LEU A 447
 None
 1.04A 5dxgB-4u98A:
undetectable		 5dxgB-4u98A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_K_IPHK101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		4 / 6 VAL A 244
HIS A 245
HIS A 303
LEU A 164
 None
 1.43A 5hrqH-4u98A:
undetectable
5hrqK-4u98A:
undetectable
5hrqL-4u98A:
undetectable		 5hrqH-4u98A:
5.24
5hrqK-4u98A:
4.02
5hrqL-4u98A:
5.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 11 LEU A 406
ALA A 407
GLU A 410
HIS A 449
LEU A 447
 None
 1.00A 5hyrB-4u98A:
undetectable		 5hyrB-4u98A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		3 / 3 ARG A  13
HIS A  11
ARG A  12
 None
 0.89A 5iaoC-4u98A:
undetectable		 5iaoC-4u98A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_1
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		6 / 12 ARG A 178
LEU A 180
GLY A 181
VAL A 200
ALA A 146
PHE A 142
 None
 0.62A 5xv7A-4u98A:
9.3		 5xv7A-4u98A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 12 PHE A 351
LEU A 406
ILE A 439
LEU A 237
LEU A 306
 None
 1.33A 5ycpA-4u98A:
undetectable		 5ycpA-4u98A:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		5 / 10 LEU A 406
ALA A 407
GLU A 410
HIS A 449
LEU A 447
 None
 1.08A 6cbzB-4u98A:
undetectable		 6cbzB-4u98A:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 4u98 MALTOKINASE
(Mycolicibacteriu
m
vanbaalenii) 		4 / 6 LEU A 308
ALA A 214
LEU A 348
SER A 234
 None
 0.88A 6f88B-4u98A:
undetectable		 6f88B-4u98A:
9.98