SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ua3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 4ua3 UNCHARACTERIZED
N-ACETYLTRANSFERASE
C825.04C
(Schizosaccharomy
ces
pombe) 		4 / 7 SER A  67
ASP A 192
GLU A 119
GLU A  79
 None
None
COA  A 301 ( 4.7A)
None
 1.07A 1knyA-4ua3A:
undetectable
1knyB-4ua3A:
undetectable		 1knyA-4ua3A:
22.93
1knyB-4ua3A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_B_KANB559_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 4ua3 UNCHARACTERIZED
N-ACETYLTRANSFERASE
C825.04C
(Schizosaccharomy
ces
pombe) 		4 / 8 GLU A  79
SER A  67
ASP A 192
GLU A 119
 None
None
None
COA  A 301 ( 4.7A)
 1.00A 1knyA-4ua3A:
undetectable
1knyB-4ua3A:
undetectable		 1knyA-4ua3A:
22.93
1knyB-4ua3A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4ua3 UNCHARACTERIZED
N-ACETYLTRANSFERASE
C825.04C
(Schizosaccharomy
ces
pombe) 		5 / 11 LEU A  31
LEU A  25
ALA A 143
VAL A  38
LEU A 135
 None
 1.42A 1kt7A-4ua3A:
undetectable		 1kt7A-4ua3A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RI4_A_SAMA299_0
(MRNA CAPPING ENZYME)		 4ua3 UNCHARACTERIZED
N-ACETYLTRANSFERASE
C825.04C
(Schizosaccharomy
ces
pombe) 		5 / 12 GLY A 100
ILE A  88
TYR A  41
GLN A  51
TYR A  87
 None
 1.20A 1ri4A-4ua3A:
undetectable		 1ri4A-4ua3A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4ua3 UNCHARACTERIZED
N-ACETYLTRANSFERASE
C825.04C
(Schizosaccharomy
ces
pombe) 		5 / 9 LEU A 102
LEU A 136
LEU A 135
ILE A 117
TYR A 166
 None
 1.05A 2f7aB-4ua3A:
1.9		 2f7aB-4ua3A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1507_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4ua3 UNCHARACTERIZED
N-ACETYLTRANSFERASE
C825.04C
(Schizosaccharomy
ces
pombe) 		3 / 3 ARG A 145
LYS A  23
ARG A 146
 None
 1.41A 3w1wA-4ua3A:
undetectable
3w1wB-4ua3A:
undetectable		 3w1wA-4ua3A:
18.70
3w1wB-4ua3A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ua3 UNCHARACTERIZED
N-ACETYLTRANSFERASE
C825.04C
(Schizosaccharomy
ces
pombe) 		4 / 8 ASP A 106
THR A 107
HIS A 174
LEU A  85
 None
 0.98A 5b1bA-4ua3A:
undetectable
5b1bC-4ua3A:
undetectable
5b1bP-4ua3A:
undetectable		 5b1bA-4ua3A:
16.40
5b1bC-4ua3A:
20.36
5b1bP-4ua3A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ua3 UNCHARACTERIZED
N-ACETYLTRANSFERASE
C825.04C
(Schizosaccharomy
ces
pombe) 		4 / 8 ASP A 106
THR A 107
HIS A 174
LEU A  85
 None
 1.03A 5x19A-4ua3A:
undetectable
5x19C-4ua3A:
undetectable
5x19P-4ua3A:
undetectable		 5x19A-4ua3A:
16.40
5x19C-4ua3A:
20.36
5x19P-4ua3A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ua3 UNCHARACTERIZED
N-ACETYLTRANSFERASE
C825.04C
(Schizosaccharomy
ces
pombe) 		4 / 7 ASP A 106
THR A 107
HIS A 174
LEU A  85
 None
 0.95A 5x1bA-4ua3A:
undetectable
5x1bC-4ua3A:
undetectable
5x1bP-4ua3A:
undetectable		 5x1bA-4ua3A:
16.40
5x1bC-4ua3A:
20.36
5x1bP-4ua3A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ua3 UNCHARACTERIZED
N-ACETYLTRANSFERASE
C825.04C
(Schizosaccharomy
ces
pombe) 		4 / 7 ASP A 106
THR A 107
HIS A 174
LEU A  85
 None
 0.98A 5x1fA-4ua3A:
undetectable
5x1fC-4ua3A:
undetectable
5x1fP-4ua3A:
undetectable		 5x1fA-4ua3A:
16.40
5x1fC-4ua3A:
20.36
5x1fP-4ua3A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ua3 UNCHARACTERIZED
N-ACETYLTRANSFERASE
C825.04C
(Schizosaccharomy
ces
pombe) 		4 / 8 LEU A  85
ASP A 106
THR A 107
HIS A 174
 None
 0.93A 6nknC-4ua3A:
undetectable
6nknN-4ua3A:
undetectable
6nknP-4ua3A:
undetectable		 6nknC-4ua3A:
20.36
6nknN-4ua3A:
16.40
6nknP-4ua3A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4ua3 UNCHARACTERIZED
N-ACETYLTRANSFERASE
C825.04C
(Schizosaccharomy
ces
pombe) 		4 / 7 ASP A 106
THR A 107
HIS A 174
LEU A  85
 None
 0.88A 6nmfA-4ua3A:
undetectable
6nmfC-4ua3A:
undetectable
6nmfP-4ua3A:
undetectable		 6nmfA-4ua3A:
16.40
6nmfC-4ua3A:
20.36
6nmfP-4ua3A:
20.36