SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4uao'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A4G_B_ZMRB466_2 (NEURAMINIDASE)	4uao	IMMUNOGLOBULIN R31C2 LIGHT CHAIN IMMUNOGLOBULIN R31C2 VH AND CH1 REGIONS (Rattus norvegicus)	3 / 3	ASP C 101 ARG B 46 ILE B 34	None	0.88A	1a4gB-4uaoC: undetectable	1a4gB-4uaoC: 20.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1ZEA_A_DHIA6_0 (MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2)	4uao	IMMUNOGLOBULIN R31C2 VH AND CH1 REGIONS (Rattus norvegicus)	3 / 3	TRP C 47 ARG C 95 PHE C 100	None	1.25A	1zeaH-4uaoC: 24.8 1zeaL-4uaoC: 15.1	1zeaH-4uaoC: 67.87 1zeaL-4uaoC: 26.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P6H_A_IBPA133_1 (FATTY ACID-BINDING PROTEIN, ADIPOCYTE)	4uao	IMMUNOGLOBULIN R31C2 LIGHT CHAIN (Rattus norvegicus)	4 / 7	PHE B 62 MET B 47 ILE B 21 VAL B 19	None	0.95A	3p6hA-4uaoB: undetectable	3p6hA-4uaoB: 23.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4M93_B_ACTB303_0 (S25-26 FAB (IGG1K) HEAVY CHAIN S25-26 FAB (IGG1K) LIGHT CHAIN)	4uao	IMMUNOGLOBULIN R31C2 LIGHT CHAIN IMMUNOGLOBULIN R31C2 VH AND CH1 REGIONS (Rattus norvegicus; Rattus norvegicus)	4 / 5	GLY C 127 ALA C 129 PHE B 209 GLU B 213	None	0.94A	4m93B-4uaoC: 22.8 4m93C-4uaoC: 16.3	4m93B-4uaoC: 67.87 4m93C-4uaoC: 25.20

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A4G_B_ZMRB466_2","NEURAMINIDASE","4uao","IMMUNOGLOBULIN R31C2 LIGHT CHAIN;IMMUNOGLOBULIN R31C2 VH AND CH1 REGIONS","Rattus norvegicus",3,"ASP C 101;ARG B  46;ILE B  34","None","0.88A","1a4gB-4uaoC:undetectable","1a4gB-4uaoC:20.30"],["1ZEA_A_DHIA6_0","MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN;MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN;SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2","4uao","IMMUNOGLOBULIN R31C2 VH AND CH1 REGIONS","Rattus norvegicus",3,"TRP C  47;ARG C  95;PHE C 100","None","1.25A","1zeaH-4uaoC:24.8;1zeaL-4uaoC:15.1","1zeaH-4uaoC:67.87;1zeaL-4uaoC:26.83"],["3P6H_A_IBPA133_1","FATTY ACID-BINDING PROTEIN, ADIPOCYTE","4uao","IMMUNOGLOBULIN R31C2 LIGHT CHAIN","Rattus norvegicus",4,"PHE B  62;MET B  47;ILE B  21;VAL B  19","None","0.95A","3p6hA-4uaoB:undetectable","3p6hA-4uaoB:23.26"],["4M93_B_ACTB303_0","S25-26 FAB (IGG1K) HEAVY CHAIN;S25-26 FAB (IGG1K) LIGHT CHAIN","4uao","IMMUNOGLOBULIN R31C2 LIGHT CHAIN;IMMUNOGLOBULIN R31C2 VH AND CH1 REGIONS","Rattus norvegicus;Rattus norvegicus",4,"GLY C 127;ALA C 129;PHE B 209;GLU B 213","None","0.94A","4m93B-4uaoC:22.8;4m93C-4uaoC:16.3","4m93B-4uaoC:67.87;4m93C-4uaoC:25.20"]]